Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo H Yin, CQ Song, JR Dorkin, LJ Zhu, Y Li, Q Wu, A Park, J Yang, S Suresh, ... Nature biotechnology 34 (3), 328-333, 2016 | 933 | 2016 |
Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing H Yin, CQ Song, S Suresh, Q Wu, S Walsh, LH Rhym, E Mintzer, ... Nature biotechnology 35 (12), 1179-1187, 2017 | 471 | 2017 |
miR-1289 and “Zipcode”-like sequence enrich mRNAs in microvesicles MF Bolukbasi, A Mizrak, GB Ozdener, S Madlener, T Ströbel, EP Erkan, ... Molecular Therapy-Nucleic Acids 1, e10, 2012 | 384 | 2012 |
Genetically engineered microvesicles carrying suicide mRNA/protein inhibit schwannoma tumor growth A Mizrak, MF Bolukbasi, GB Ozdener, GJ Brenner, S Madlener, EP Erkan, ... Molecular Therapy 21 (1), 101-108, 2013 | 353 | 2013 |
DNA-binding-domain fusions enhance the targeting range and precision of Cas9 MF Bolukbasi, A Gupta, S Oikemus, AG Derr, M Garber, MH Brodsky, ... Nature methods 12 (12), 1150-1156, 2015 | 162 | 2015 |
Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery MF Bolukbasi, A Gupta, SA Wolfe Nature methods 13 (1), 41-50, 2016 | 146 | 2016 |
Enhanced Cas12a editing in mammalian cells and zebrafish P Liu, K Luk, M Shin, F Idrizi, S Kwok, B Roscoe, E Mintzer, S Suresh, ... Nucleic acids research 47 (8), 4169-4180, 2019 | 100 | 2019 |
Orthogonal Cas9–Cas9 chimeras provide a versatile platform for genome editing MF Bolukbasi, P Liu, K Luk, SF Kwok, A Gupta, N Amrani, EJ Sontheimer, ... Nature communications 9 (1), 4856, 2018 | 39 | 2018 |
Cas9-DNA targeting unit chimeras SA Wolfe, MF Bolukbasi, A Gupta, EJ Sontheimer, N Amrani US Patent 10,190,106, 2019 | 32 | 2019 |
SIR proteins create compact heterochromatin fibers CLP SG Swygert, S Senapati, MF Bolukbasi, SA Wolfe,S Lindsay Proceedings of the National Academy of Sciences of the United States of …, 2018 | 23* | 2018 |
Microvesicle-mediated delivery of therapeutic molecules XO Breakefield, MF Bolukbasi, A Mizrak, O Saydam US Patent App. 14/384,056, 2013 | 4 | 2013 |
Targeting RNAs to microvesicles O Saydam, MF Bolukbasi, A Mizrak, XO Breakefield US Patent 9,879,254, 2018 | 2 | 2018 |
CAS9-CAS9 fusion proteins SA Wolfe, MF Bolukbasi, A Gupta, EJ Sontheimer, N Amrani US Patent 11,028,380, 2021 | | 2021 |
Targeting bcl11a distal regulatory elements with a cas9-cas9 fusion for fetal hemoglobin reinduction DE BAUER, S WOLFE, MF BOLUKBASI, B ROSCOE, LIU Pengpeng, ... | | 2019 |
Development of Chimeric Cas9 Nucleases for Accurate and Flexible Genome Editing MF Bolukbasi | | 2017 |