Microvesicle-and exosome-mediated drug delivery enhances the cytotoxicity of Paclitaxel in autologous prostate cancer cells H Saari, E Lázaro-Ibáñez, T Viitala, E Vuorimaa-Laukkanen, P Siljander, ... Journal of controlled release 220, 727-737, 2015 | 553 | 2015 |
miR-1289 and “Zipcode”-like sequence enrich mRNAs in microvesicles MF Bolukbasi, A Mizrak, GB Ozdener, S Madlener, T Ströbel, EP Erkan, ... Molecular Therapy-Nucleic Acids 1, 2012 | 384 | 2012 |
KRAS-dependent sorting of miRNA to exosomes DJ Cha, JL Franklin, Y Dou, Q Liu, JN Higginbotham, M Demory Beckler, ... Elife 4, e07197, 2015 | 374 | 2015 |
Genetically engineered microvesicles carrying suicide mRNA/protein inhibit schwannoma tumor growth A Mizrak, MF Bolukbasi, GB Ozdener, GJ Brenner, S Madlener, EP Erkan, ... Molecular Therapy 21 (1), 101-108, 2013 | 353 | 2013 |
Exosomes as therapeutics: the implications of molecular composition and exosomal heterogeneity SW Ferguson, J Nguyen Journal of Controlled Release 228, 179-190, 2016 | 341 | 2016 |
Downregulated microRNA-200a in meningiomas promotes tumor growth by reducing E-cadherin and activating the Wnt/β-catenin signaling pathway O Saydam, Y Shen, T Würdinger, O Senol, E Boke, MF James, ... Molecular and cellular biology 29 (21), 5923-5940, 2009 | 328 | 2009 |
Engineered exosomes as vehicles for biologically active proteins U Sterzenbach, U Putz, LH Low, J Silke, SS Tan, J Howitt Molecular Therapy 25 (6), 1269-1278, 2017 | 298 | 2017 |
Possibility of exosome-based therapeutics and challenges in production of exosomes eligible for therapeutic application T Yamashita, Y Takahashi, Y Takakura Biological and Pharmaceutical Bulletin 41 (6), 835-842, 2018 | 241 | 2018 |
miRNA-7 attenuation in Schwannoma tumors stimulates growth by upregulating three oncogenic signaling pathways O Saydam, O Senol, T Würdinger, A Mizrak, GB Ozdener, ... Cancer research 71 (3), 852-861, 2011 | 191 | 2011 |
Determination of glutathione, glutathione reductase, glutathione peroxidase and glutathione S-transferase levels in human lung cancer tissues N Saydam, A Kirb, Ö Demir, E Hazan, Ö Oto, O Saydam, G Güner Cancer letters 119 (1), 13-19, 1997 | 169 | 1997 |
Exosomal transfer of miR-1238 contributes to temozolomide-resistance in glioblastoma J Yin, A Zeng, Z Zhang, Z Shi, W Yan, Y You EBioMedicine 42, 238-251, 2019 | 147 | 2019 |
Herpes simplex virus 1 amplicon vector-mediated siRNA targeting epidermal growth factor receptor inhibits growth of human glioma cells in vivo O Saydam, DL Glauser, I Heid, G Turkeri, M Hilbe, AH Jacobs, ... Molecular Therapy 12 (5), 803-812, 2005 | 104 | 2005 |
Comparative protein profiling reveals minichromosome maintenance (MCM) proteins as novel potential tumor markers for meningiomas O Saydam, O Senol, TBM Schaaij-Visser, TV Pham, SR Piersma, ... Journal of proteome research 9 (1), 485-494, 2010 | 84 | 2010 |
Small extracellular vesicles convey the stress-induced adaptive responses of melanoma cells M Harmati, E Gyukity-Sebestyen, G Dobra, L Janovak, I Dekany, ... Scientific reports 9 (1), 15329, 2019 | 69 | 2019 |
Essential role for mammalian apurinic/apyrimidinic (AP) endonuclease Ape1/Ref-1 in telomere maintenance S Madlener, T Ströbel, S Vose, O Saydam, BD Price, B Demple, ... Proceedings of the National Academy of Sciences 110 (44), 17844-17849, 2013 | 65 | 2013 |
Stressors alter intercellular communication and exosome profile of nasopharyngeal carcinoma cells M Harmati, Z Tarnai, G Decsi, S Kormondi, Z Szegletes, L Janovak, ... Journal of Oral Pathology & Medicine 46 (4), 259-266, 2017 | 52 | 2017 |
Extracellular vesicle-mediated suicide mRNA/protein delivery inhibits glioblastoma tumor growth in vivo EP Erkan, D Senfter, S Madlener, G Jungwirth, T Ströbel, N Saydam, ... Cancer gene therapy 24 (1), 38-44, 2017 | 52 | 2017 |
Extracellular vesicles as natural nanosized delivery systems for small-molecule drugs and genetic material: steps towards the future nanomedicines M Kotmakçı, VB Çetintaş Journal of Pharmacy & Pharmaceutical Sciences 18 (3), 396-413, 2015 | 50 | 2015 |
Nanoparticle tracking analysis H Peneder, E Punz, IA Joubert, M Geppert, M Himly Open Schools Journal for Open Science 3 (2), 2020 | 49 | 2020 |
Targeted integration of functional human ATM cDNA into genome mediated by HSV/AAV hybrid amplicon vector ML Cortés, A Oehmig, O Saydam, JD Sanford, KF Perry, C Fraefel, ... Molecular therapy 16 (1), 81-88, 2008 | 48 | 2008 |