| Molecular dynamics simulations of amyloid β-peptide (1-42): tetramer formation and membrane interactions AM Brown, DR Bevan Biophysical journal 111 (5), 937-949, 2016 | 88 | 2016 |
| Comparing atomistic molecular mechanics force fields for a difficult target: a case study on the Alzheimer’s amyloid β-peptide SR Gerben, JA Lemkul, AM Brown, DR Bevan Journal of Biomolecular Structure and Dynamics 32 (11), 1817-1832, 2014 | 87 | 2014 |
| A selective sweep in the Spike gene has driven SARS-CoV-2 human adaptation L Kang, G He, AK Sharp, X Wang, AM Brown, P Michalak, ... Cell 184 (17), 4392-4400. e4, 2021 | 76 | 2021 |
| Purine biosynthesis in archaea: variations on a theme AM Brown, SL Hoopes, RH White, CA Sarisky Biology direct 6, 1-21, 2011 | 46 | 2011 |
| Transforming sphingosine kinase 1 inhibitors into dual and sphingosine kinase 2 selective inhibitors: design, synthesis, and in vivo activity ES Childress, Y Kharel, AM Brown, DR Bevan, KR Lynch, WL Santos Journal of medicinal chemistry 60 (9), 3933-3957, 2017 | 43 | 2017 |
| Distinct control of PERIOD2 degradation and circadian rhythms by the oncoprotein and ubiquitin ligase MDM2 JJ Liu, X Zou, T Gotoh, AM Brown, L Jiang, EL Wisdom, JK Kim, ... Science Signaling 11 (556), eaau0715, 2018 | 41 | 2018 |
| Simulations of monomeric amyloid β-peptide (1–40) with varying solution conditions and oxidation state of Met35: Implications for aggregation AM Brown, JA Lemkul, N Schaum, DR Bevan Archives of biochemistry and biophysics 545, 44-52, 2014 | 41 | 2014 |
| Structure of the sensory domain of McpX from Sinorhizobium meliloti, the first known bacterial chemotactic sensor for quaternary ammonium compounds M Shrestha, KK Compton, JM Mancl, BA Webb, AM Brown, BE Scharf, ... Biochemical Journal 475 (24), 3949-3962, 2018 | 28 | 2018 |
| Insights into stabilizing forces in amyloid fibrils of differing sizes from polarizable molecular dynamics simulations DS Davidson, AM Brown, JA Lemkul Journal of molecular biology 430 (20), 3819-3834, 2018 | 27 | 2018 |
| Structure–activity relationship studies and molecular modeling of naphthalene-based sphingosine kinase 2 inhibitors MD Congdon, Y Kharel, AM Brown, SN Lewis, DR Bevan, KR Lynch, ... ACS Medicinal Chemistry Letters 7 (3), 229-234, 2016 | 27 | 2016 |
| Development of a structured undergraduate research experience: Framework and implications AM Brown, SN Lewis, DR Bevan Biochemistry and Molecular Biology Education 44 (5), 463-474, 2016 | 25 | 2016 |
| Inositol trisphosphate kinase and diphosphoinositol pentakisphosphate kinase enzymes constitute the inositol pyrophosphate synthesis pathway in plants O Adepoju, SP Williams, B Craige, CA Cridland, AK Sharpe, AM Brown, ... Biorxiv, 724914, 2019 | 24 | 2019 |
| Protein kinases in Toxoplasma gondii RY Gaji, AK Sharp, AM Brown International journal for parasitology 51 (6), 415-429, 2021 | 22 | 2021 |
| Influence of sequence and lipid type on membrane perturbation by human and rat amyloid β-peptide (1–42) AM Brown, DR Bevan Archives of biochemistry and biophysics 614, 1-13, 2017 | 22 | 2017 |
| Discovery of a small side cavity in sphingosine kinase 2 that enhances inhibitor potency and selectivity CD Sibley, EA Morris, Y Kharel, AM Brown, T Huang, DR Bevan, ... Journal of medicinal chemistry 63 (3), 1178-1198, 2020 | 20 | 2020 |
| HIV-1 Env gp41 transmembrane domain dynamics are modulated by lipid, water, and ion interactions LR Hollingsworth, JA Lemkul, DR Bevan, AM Brown Biophysical journal 115 (1), 84-94, 2018 | 15 | 2018 |
| Rosmarinic acid potently detoxifies amylin amyloid and ameliorates diabetic pathology in a transgenic rat model of type 2 diabetes L Wu, P Velander, AM Brown, Y Wang, D Liu, DR Bevan, S Zhang, B Xu ACS Pharmacology & Translational Science 4 (4), 1322-1337, 2021 | 13 | 2021 |
| Lipophilic tail modifications of 2-(hydroxymethyl) pyrrolidine scaffold reveal dual sphingosine kinase 1 and 2 inhibitors H Li, CD Sibley, Y Kharel, T Huang, AM Brown, LG Wonilowicz, DR Bevan, ... Bioorganic & medicinal chemistry 30, 115941, 2021 | 13 | 2021 |
| In Silico Characterization of Structural Distinctions between Isoforms of Human and Mouse Sphingosine Kinases for Accelerating Drug Discovery BL Worrell, AM Brown, WL Santos, DR Bevan Journal of chemical information and modeling 59 (5), 2339-2351, 2019 | 12 | 2019 |
| Wildlife exposure to SARS-CoV-2 across a human use gradient AR Goldberg, KE Langwig, J Marano, P Rai, AK Sharp, KL Brown, A Ceci, ... BioRXiV, 2022.11. 04.515237, 2022 | 11 | 2022 |
David BevanProfessor of BiochemistryVerified email at vt.edu
