| Potent allosteric dengue virus NS5 polymerase inhibitors: mechanism of action and resistance profiling SP Lim, CG Noble, CC Seh, TS Soh, A El Sahili, GKY Chan, J Lescar, ... PLoS pathogens 12 (8), e1005737, 2016 | 150 | 2016 |
| Dengue Virus Non-Structural Protein 5. A El Sahili, J Lescar Viruses 9 (4), 2017 | 135 | 2017 |
| Structure of the human metapneumovirus polymerase phosphoprotein complex J Pan, X Qian, S Lattmann, A El Sahili, TH Yeo, H Jia, T Cressey, ... Nature 577 (7789), 275-279, 2020 | 94 | 2020 |
| Structural determinants for peptide-bond formation by asparaginyl ligases X Hemu, A El Sahili, S Hu, K Wong, Y Chen, YH Wong, X Zhang, A Serra, ... Proceedings of the National Academy of Sciences 116 (24), 11737-11746, 2019 | 93 | 2019 |
| Allosteric pyruvate kinase-based “logic gate” synergistically senses energy and sugar levels in Mycobacterium tuberculosis W Zhong, L Cui, BC Goh, Q Cai, P Ho, YH Chionh, M Yuan, AE Sahili, ... Nature communications 8 (1), 1986, 2017 | 60 | 2017 |
| Non-nucleoside inhibitors of Zika virus RNA-dependent RNA polymerase A Gharbi-Ayachi, S Santhanakrishnan, YH Wong, KWK Chan, ST Tan, ... Journal of Virology 94 (21), 10.1128/jvi. 00794-20, 2020 | 45 | 2020 |
| NS5 from dengue virus serotype 2 can adopt a conformation analogous to that of its Zika virus and Japanese encephalitis virus homologues A El Sahili, TS Soh, J Schiltz, A Gharbi-Ayachi, CC Seh, PY Shi, SP Lim, ... Journal of virology 94 (1), 10.1128/jvi. 01294-19, 2019 | 42 | 2019 |
| Agrobacterium Uses a Unique Ligand-Binding Mode for Trapping Opines and Acquiring A Competitive Advantage in the Niche Construction on Plant Host J Lang, A Vigouroux, S Planamente, A El Sahili, P Blin, M Aumont-Nicaise, ... PLoS Pathogens 10 (10), e1004444, 2014 | 39 | 2014 |
| Plasmodium vivax binds host CD98hc (SLC3A2) to enter immature red blood cells B Malleret, A El Sahili, MZ Tay, G Carissimo, ASM Ong, W Novera, J Lin, ... Nature microbiology 6 (8), 991-999, 2021 | 37 | 2021 |
| A Pyranose-2-Phosphate Motif Is Responsible for Both Antibiotic Import and Quorum-Sensing Regulation in Agrobacterium tumefaciens A El Sahili, SZ Li, J Lang, C Virus, S Planamente, M Ahmar, ... PLoS Pathogens 11 (8), e1005071, 2015 | 36 | 2015 |
| Turning an asparaginyl endopeptidase into a peptide ligase X Hemu, A El Sahili, S Hu, X Zhang, A Serra, BC Goh, DA Darwis, ... ACS catalysis 10 (15), 8825-8834, 2020 | 35 | 2020 |
| Targeting the Bacterial Epitranscriptome for Antibiotic Development: Discovery of Novel tRNA-(N1G37) Methyltransferase (TrmD) Inhibitors W Zhong, A Koay, A Ngo, Y Li, Q Nah, YH Wong, YH Chionh, HQ Ng, ... ACS infectious diseases 5 (3), 326-335, 2019 | 35 | 2019 |
| Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A* 11: 01 Y Gu, YH Wong, CW Liew, CEZ Chan, TM Murali, J Yap, CT Too, ... Nature communications 10 (1), 893, 2019 | 32 | 2019 |
| Modulation of Lymphocyte Potassium Channel KV1.3 by Membrane-Penetrating, Joint-Targeting Immunomodulatory Plant Defensin ST Ong, S Bajaj, MR Tanner, SC Chang, B Krishnarjuna, XR Ng, ... ACS pharmacology & translational science 3 (4), 720-736, 2020 | 19 | 2020 |
| Engineering SARS-CoV-2 specific cocktail antibodies into a bispecific format improves neutralizing potency and breadth Z Ku, X Xie, J Lin, P Gao, B Wu, A El Sahili, H Su, Y Liu, X Ye, EY Tan, ... Nature communications 13 (1), 5552, 2022 | 18 | 2022 |
| Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3 WW Phoo, A El Sahili, ZZ Zhang, MW Chen, CW Liew, J Lescar, ... Antiviral research 182, 104900, 2020 | 17 | 2020 |
| Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa J Jaroensuk, YH Wong, W Zhong, CW Liew, S Maenpuen, AE Sahili, ... Rna 25 (11), 1481-1496, 2019 | 17 | 2019 |
| The protein kinase CK2 catalytic domain from Plasmodium falciparum: crystal structure, tyrosine kinase activity and inhibition D Ruiz-Carrillo, J Lin, A El Sahili, M Wei, SK Sze, PCF Cheung, C Doerig, ... Scientific Reports 8 (1), 7365, 2018 | 17 | 2018 |
| Structural basis for high specificity of octopine binding in the plant pathogen Agrobacterium tumefaciens A Vigouroux, A El Sahili, J Lang, M Aumont-Nicaise, Y Dessaux, D Faure, ... Scientific Reports 7 (1), 18033, 2017 | 16 | 2017 |
| Functional evolution in orthologous cell-encoded RNA-dependent RNA polymerases X Qian, FM Hamid, A El Sahili, DA Darwis, YH Wong, S Bhushan, ... Journal of Biological Chemistry 291 (17), 9295-9309, 2016 | 14 | 2016 |
