Molecular-crowding effects on single-molecule RNA folding/unfolding thermodynamics and kinetics NF Dupuis, ED Holmstrom, DJ Nesbitt Proceedings of the National Academy of Sciences 111 (23), 8464-8469, 2014 | 160 | 2014 |
Synthesis and applications of RNAs with position-selective labelling and mosaic composition Y Liu, E Holmstrom, J Zhang, P Yu, J Wang, MA Dyba, D Chen, J Ying, ... Nature 522 (7556), 368-372, 2015 | 118 | 2015 |
Single-molecule kinetics reveal cation-promoted DNA duplex formation through ordering of single-stranded helices NF Dupuis, ED Holmstrom, DJ Nesbitt Biophysical journal 105 (3), 756-766, 2013 | 118 | 2013 |
The SARS-CoV-2 conserved macrodomain is a mono-ADP-ribosylhydrolase YMO Alhammad, MM Kashipathy, A Roy, JP Gagné, P McDonald, P Gao, ... Journal of virology 95 (3), 10.1128/jvi. 01969-20, 2021 | 111 | 2021 |
Transition path times of coupled folding and binding reveal the formation of an encounter complex F Sturzenegger, F Zosel, ED Holmstrom, KJ Buholzer, DE Makarov, ... Nature communications 9 (1), 4708, 2018 | 101 | 2018 |
Binding without folding–the biomolecular function of disordered polyelectrolyte complexes B Schuler, A Borgia, MB Borgia, PO Heidarsson, ED Holmstrom, D Nettels, ... Current opinion in structural biology 60, 66-76, 2020 | 87 | 2020 |
Entropic origin of Mg2+-facilitated RNA folding JL Fiore, ED Holmstrom, DJ Nesbitt Proceedings of the National Academy of Sciences 109 (8), 2902-2907, 2012 | 67 | 2012 |
Disordered RNA chaperones can enhance nucleic acid folding via local charge screening ED Holmstrom, Z Liu, D Nettels, RB Best, B Schuler Nature communications 10 (1), 2453, 2019 | 66 | 2019 |
Accurate transfer efficiencies, distance distributions, and ensembles of unfolded and intrinsically disordered proteins from single-molecule FRET ED Holmstrom, A Holla, W Zheng, D Nettels, RB Best, B Schuler Methods in enzymology 611, 287-325, 2018 | 58 | 2018 |
Mechanistic insights into cofactor-dependent coupling of RNA folding and mRNA transcription/translation by a cobalamin riboswitch JT Polaski, ED Holmstrom, DJ Nesbitt, RT Batey Cell reports 15 (5), 1100-1110, 2016 | 50 | 2016 |
Single-molecule conformational dynamics of a biologically functional hydroxocobalamin riboswitch ED Holmstrom, JT Polaski, RT Batey, DJ Nesbitt Journal of the American Chemical Society 136 (48), 16832-16843, 2014 | 50 | 2014 |
Thermodynamic origins of monovalent facilitated RNA folding ED Holmstrom, JL Fiore, DJ Nesbitt Biochemistry 51 (18), 3732-3743, 2012 | 39 | 2012 |
Kinetic and thermodynamic origins of osmolyte-influenced nucleic acid folding ED Holmstrom, NF Dupuis, DJ Nesbitt The Journal of Physical Chemistry B 119 (9), 3687-3696, 2015 | 36 | 2015 |
Incorporation of isotopic, fluorescent, and heavy-atom-modified nucleotides into RNAs by position-selective labeling of RNA Y Liu, E Holmstrom, P Yu, K Tan, X Zuo, DJ Nesbitt, R Sousa, JR Stagno, ... Nature protocols 13 (5), 987-1005, 2018 | 35 | 2018 |
Biophysical insights from temperature-dependent single-molecule förster resonance energy transfer ED Holmstrom, DJ Nesbitt Annual Review of Physical Chemistry 67 (1), 441-465, 2016 | 30 | 2016 |
Pulsed IR heating studies of single-molecule DNA duplex dissociation kinetics and thermodynamics ED Holmstrom, NF Dupuis, DJ Nesbitt Biophysical Journal 106 (1), 220-231, 2014 | 29 | 2014 |
The role of counterion valence and size in GAAA tetraloop–receptor docking/undocking kinetics JL Fiore, ED Holmstrom, LR Fiegland, JH Hodak, DJ Nesbitt Journal of molecular biology 423 (2), 198-216, 2012 | 28 | 2012 |
Recognition of single-stranded nucleic acids by small-molecule splicing modulators Z Tang, S Akhter, A Ramprasad, X Wang, M Reibarkh, J Wang, S Aryal, ... Nucleic Acids Research 49 (14), 7870-7883, 2021 | 27 | 2021 |
Real-Time Infrared Overtone Laser Control of Temperature in Picoliter H2O Samples: “Nanobathtubs” for Single Molecule Microscopy ED Holmstrom, DJ Nesbitt The journal of physical chemistry letters 1 (15), 2264-2268, 2010 | 27 | 2010 |
Conformational plasticity of hepatitis C virus core protein enables RNA-induced formation of nucleocapsid-like particles ED Holmstrom, D Nettels, B Schuler Journal of molecular biology 430 (16), 2453-2467, 2018 | 25 | 2018 |