A novel suicide vector and its use in construction of insertion mutations: osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR VL Miller, JJ Mekalanos Journal of bacteriology 170 (6), 2575-2583, 1988 | 2587 | 1988 |
Lysogenic conversion by a filamentous phage encoding cholera toxin MK Waldor, JJ Mekalanos Science 272 (5270), 1910-1914, 1996 | 2476 | 1996 |
DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae JF Heidelberg, JA Eisen, WC Nelson, RA Clayton, ML Gwinn, RJ Dodson, ... Nature 406 (6795), 477-483, 2000 | 2226 | 2000 |
Epidemiology, Genetics, and Ecology of ToxigenicVibrio cholerae SM Faruque, MJ Albert, JJ Mekalanos Microbiology and molecular biology reviews 62 (4), 1301-1314, 1998 | 1437 | 1998 |
Identification of a conserved bacterial protein secretion system in Vibrio cholerae using the Dictyostelium host model system S Pukatzki, AT Ma, D Sturtevant, B Krastins, D Sarracino, WC Nelson, ... Proceedings of the National Academy of Sciences 103 (5), 1528-1533, 2006 | 1377 | 2006 |
Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin. RK Taylor, VL Miller, DB Furlong, JJ Mekalanos Proceedings of the National Academy of Sciences 84 (9), 2833-2837, 1987 | 1307 | 1987 |
A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus JD Mougous, ME Cuff, S Raunser, A Shen, M Zhou, CA Gifford, ... Science 312 (5779), 1526-1530, 2006 | 1276 | 2006 |
A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence. SI Miller, AM Kukral, JJ Mekalanos Proceedings of the National Academy of Sciences 86 (13), 5054-5058, 1989 | 1219 | 1989 |
Environmental signals controlling expression of virulence determinants in bacteria JJ Mekalanos Journal of bacteriology 174 (1), 1-7, 1992 | 1099 | 1992 |
Quorum-sensing regulators control virulence gene expression in Vibrio cholerae J Zhu, MB Miller, RE Vance, M Dziejman, BL Bassler, JJ Mekalanos Proceedings of the National Academy of Sciences 99 (5), 3129-3134, 2002 | 1072 | 2002 |
The origin of the Haitian cholera outbreak strain CS Chin, J Sorenson, JB Harris, WP Robins, RC Charles, ... New England Journal of Medicine 364 (1), 33-42, 2011 | 930 | 2011 |
Toxin, toxin-coregulated pili, and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans. DA Herrington, RH Hall, G Losonsky, JJ Mekalanos, RK Taylor, ... The Journal of experimental medicine 168 (4), 1487-1492, 1988 | 916 | 1988 |
Selection of bacterial virulence genes that are specifically induced in host tissues MJ Mahan, JM Slauch, JJ Mekalanos Science 259 (5095), 686-688, 1993 | 902 | 1993 |
Type VI secretion system translocates a phage tail spike-like protein into target cells where it cross-links actin S Pukatzki, AT Ma, AT Revel, D Sturtevant, JJ Mekalanos Proceedings of the National Academy of Sciences 104 (39), 15508-15513, 2007 | 846 | 2007 |
Cholera toxin genes: nucleotide sequence, deletion analysis and vaccine development JJ Mekalanos, DJ Swartz, GDN Pearson, N Harford, F Groyne, M de Wilde Nature 306 (5943), 551-557, 1983 | 812 | 1983 |
Coordinate regulation and sensory transduction in the control of bacterial virulence JF Miller, JJ Mekalanos, S Falkow Science 243 (4893), 916-922, 1989 | 766 | 1989 |
Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin PG Leiman, M Basler, UA Ramagopal, JB Bonanno, JM Sauder, ... Proceedings of the National Academy of Sciences 106 (11), 4154-4159, 2009 | 749 | 2009 |
Type VI secretion requires a dynamic contractile phage tail-like structure M Basler, M Pilhofer, GP Henderson, GJ Jensen, JJ Mekalanos Nature 483 (7388), 182-186, 2012 | 743 | 2012 |
Cholera toxin transcriptional activator ToxR is a transmembrane DNA binding protein VL Miller, RK Taylor, JJ Mekalanos cell 48 (2), 271-279, 1987 | 741 | 1987 |
Quorum sensing-dependent biofilms enhance colonization in Vibrio cholerae J Zhu, JJ Mekalanos Developmental cell 5 (4), 647-656, 2003 | 687 | 2003 |