Altered Reactivity of Superoxide Dismutase in Familial Amyotrophic Lateral Sclerosis M Wiedau-Pazo, JJ Goto, S Rabizadeah, EB Gralla, JA Roe, MK Lee, ... Science 271 (5248), 515-518, 1996 | 949 | 1996 |
Decreased metallation and activity in subsets of mutant superoxide dismutases associated with familial amyotrophic lateral sclerosis LJ Hayward, JA Rodriguez, JW Kim, A Tiwari, JJ Goto, DE Cabelli, ... Journal of Biological Chemistry 277 (18), 15923-15931, 2002 | 443 | 2002 |
The dark side of dioxygen biochemistry JS Valentine, DL Wertz, TJ Lyons, LL Liou, JJ Goto, EB Gralla Current opinion in chemical biology 2 (2), 253-262, 1998 | 302 | 1998 |
Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein TJ Lyons, H Liu, JJ Goto, A Nersissian, JA Roe, JA Graden, C Cafe, ... Proceedings of the National Academy of Sciences 93 (22), 12240-12244, 1996 | 239 | 1996 |
Loss of in vitro metal ion binding specificity in mutant copper-zinc superoxide dismutases associated with familial amyotrophic lateral sclerosis JJ Goto, H Zhu, RJ Sanchez, A Nersissian, EB Gralla, JS Valentine, ... Journal of Biological Chemistry 275 (2), 1007-1014, 2000 | 209 | 2000 |
Unusual Trigonal-Planar Copper Configuration Revealed in the Atomic Structure of Yeast Copper−Zinc Superoxide Dismutase NL Ogihara, HE Parge, PJ Hart, MS Weiss, JJ Goto, BR Crane, J Tsang, ... Biochemistry 35 (7), 2316-2321, 1996 | 118 | 1996 |
Copper (2+) binding to the surface residue cysteine 111 of His46Arg human copper− zinc superoxide dismutase, a familial amyotrophic lateral sclerosis mutant H Liu, H Zhu, DK Eggers, AM Nersissian, KF Faull, JJ Goto, J Ai, ... Biochemistry 39 (28), 8125-8132, 2000 | 114 | 2000 |
Reactions of hydrogen peroxide with familial amyotrophic lateral sclerosis mutant human copper-zinc superoxide dismutases studied by pulse radiolysis JJ Goto, EB Gralla, JS Valentine, DE Cabelli Journal of Biological Chemistry 273 (46), 30104-30109, 1998 | 87 | 1998 |
Metal ion reconstitution studies of yeast copper-zinc superoxide dismutase: the" phantom" subunit and the possible role of Lys7p TJ Lyons, A Nersissian, JJ Goto, H Zhu, EB Gralla, JS Valentine JBIC Journal of Biological Inorganic Chemistry 3 (6), 650-662, 1998 | 57 | 1998 |
In vivo peroxidative activity of FALS-mutant human CuZnSODs expressed in yeast JA Roe, M Wiedau-Pazos, VN Moy, JJ Goto, EB Gralla, JS Valentine Free Radical Biology and Medicine 32 (2), 169-174, 2002 | 45 | 2002 |
The role of the low-density lipoprotein receptor-related protein (LRP1) in alzheimer’s Aβ generation JJ Goto, RE Tanzi Journal of Molecular Neuroscience 19 (1-2), 37-41, 2002 | 41 | 2002 |
Cell death mechanisms in ALS DE Bredesen, M Wiedau-Pazos, JJ Goto, S Rabizadeh, JA Roe, EB Gralla, ... Neurology 47 (4 Suppl 2), 36S-39S, 1996 | 39 | 1996 |
Chemistry and Chemical Equilibrium Dynamics of BMAA and Its Carbamate Adducts P Diaz-parga, JJ Goto, VV Krishnan Neurotoxicity research 33 (1), 76-86, 2018 | 31 | 2018 |
The physiological effect of ingested β-N-methylamino-L-alanine on a glutamatergic synapse in an in vivo preparation JJ Goto, JH Koenig, K Ikeda Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2012 | 31 | 2012 |
NMR chromatography: molecular diffusion in the presence of pulsed field gradients in analytical chemistry applications KA Heisel, JJ Goto, VV Krishnan American Journal of Analytical Chemistry 2012, 2012 | 28 | 2012 |
Directed evolution of the escherichia coli camp receptor protein at the camp pocket SM Gunasekara, MN Hicks, J Park, CL Brooks, J Serate, CV Saunders, ... Journal of Biological Chemistry 290 (44), 26587-26596, 2015 | 20 | 2015 |
Equilibrium dynamics of β-n-methylamino-l-alanine (bmaa) and its carbamate adducts at physiological conditions D Zimmerman, JJ Goto, VV Krishnan PloS one 11 (8), 2016 | 17 | 2016 |
Method of modulating radical formation by mutant cuznsod enzymes DE Bredesen, JS Valentine, M Wiedau-Pazos, JJ Goto, EB Gralla US Patent 5,834,457, 1998 | 17 | 1998 |
Modulations in restricted amide rotation by steric induced conformational trapping VV Krishnan, WB Thompson, JJ Goto, K Maitra, S Maitra Chemical physics letters 523, 124-127, 2012 | 15 | 2012 |
On the Differential Roles of Mg 2+, Zn 2+, and Cu 2+ in the Equilibrium of β-N-Methyl-Amino-L-Alanine (BMAA) and its Carbamates P Diaz-parga, JJ Goto, VV Krishnan Neurotoxicity Research, 1-11, 2020 | 10 | 2020 |