| Succinate is an inflammatory signal that induces IL-1β through HIF-1α GM Tannahill, AM Curtis, J Adamik, EM Palsson-McDermott, ... Nature 496 (7444), 238-242, 2013 | 3387 | 2013 |
| Prolyl hydroxylase-1 negatively regulates IκB kinase-β, giving insight into hypoxia-induced NFκB activity EP Cummins, E Berra, KM Comerford, A Ginouves, KT Fitzgerald, ... Proceedings of the National Academy of Sciences 103 (48), 18154-18159, 2006 | 897 | 2006 |
| Hypoxia-responsive transcription factors EP Cummins, CT Taylor Pflügers Archiv 450, 363-371, 2005 | 569 | 2005 |
| The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis EP Cummins, F Seeballuck, SJ Keely, NE Mangan, JJ Callanan, ... Gastroenterology 134 (1), 156-165. e1, 2008 | 452 | 2008 |
| MicroRNA-155 promotes resolution of hypoxia-inducible factor 1α activity during prolonged hypoxia U Bruning, L Cerone, Z Neufeld, SF Fitzpatrick, A Cheong, CC Scholz, ... Molecular and cellular biology 31 (19), 4087-4096, 2011 | 339 | 2011 |
| Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function MM Tambuwala, EP Cummins, CR Lenihan, J Kiss, M Stauch, CC Scholz, ... Gastroenterology 139 (6), 2093-2101, 2010 | 224 | 2010 |
| PGC-1α is coupled to HIF-1α-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells KA O'Hagan, S Cocchiglia, AV Zhdanov, MM Tambuwala, EP Cummins, ... Proceedings of the National Academy of Sciences 106 (7), 2188-2193, 2009 | 220 | 2009 |
| PGC-1α is coupled to HIF-1α-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells KA O'Hagan, S Cocchiglia, AV Zhdanov, MM Tambuwala, EP Cummins, ... Proceedings of the National Academy of Sciences 106 (7), 2188-2193, 2009 | 220 | 2009 |
| The role of NF‐κB in hypoxia‐induced gene expression CT Taylor, EP Cummins Annals of the New York Academy of Sciences 1177 (1), 178-184, 2009 | 218 | 2009 |
| An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia SF Fitzpatrick, MM Tambuwala, U Bruning, B Schaible, CC Scholz, ... The Journal of Immunology 186 (2), 1091-1096, 2011 | 194 | 2011 |
| Hypoxia-dependent regulation of inflammatory pathways in immune cells CT Taylor, G Doherty, PG Fallon, EP Cummins The Journal of clinical investigation 126 (10), 3716-3724, 2016 | 186 | 2016 |
| Protein hydroxylation by hypoxia-inducible factor (HIF) hydroxylases: unique or ubiquitous? MJ Strowitzki, EP Cummins, CT Taylor Cells 8 (5), 384, 2019 | 183 | 2019 |
| Regulation of IL-1β–induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways CC Scholz, MAS Cavadas, MM Tambuwala, E Hams, J Rodríguez, ... Proceedings of the National Academy of Sciences 110 (46), 18490-18495, 2013 | 182 | 2013 |
| The role of HIF in immunity and inflammation EP Cummins, CE Keogh, D Crean, CT Taylor Molecular aspects of medicine 47, 24-34, 2016 | 151 | 2016 |
| c-Jun NH2-terminal kinase activation contributes to hypoxia-inducible factor 1α–dependent P-glycoprotein expression in hypoxia KM Comerford, EP Cummins, CT Taylor Cancer research 64 (24), 9057-9061, 2004 | 145 | 2004 |
| A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network LK Nguyen, MAS Cavadas, CC Scholz, SF Fitzpatrick, U Bruning, ... Journal of cell science 126 (6), 1454-1463, 2013 | 139 | 2013 |
| Carbon dioxide-sensing in organisms and its implications for human disease EP Cummins, AC Selfridge, PH Sporn, JI Sznajder, CT Taylor Cellular and Molecular Life Sciences 71, 831-845, 2014 | 138 | 2014 |
| Hypoxia activates NF-κB–dependent gene expression through the canonical signaling pathway KM Oliver, JF Garvey, CT Ng, DJ Veale, U Fearon, EP Cummins, ... Antioxidants & redox signaling 11 (9), 2057-2064, 2009 | 136 | 2009 |
| NF-κB links CO2 sensing to innate immunity and inflammation in mammalian cells EP Cummins, KM Oliver, CR Lenihan, SF Fitzpatrick, U Bruning, ... The Journal of Immunology 185 (7), 4439-4445, 2010 | 123 | 2010 |
| Gremlin plays a key role in the pathogenesis of pulmonary hypertension E Cahill, CM Costello, SC Rowan, S Harkin, K Howell, MO Leonard, ... Circulation 125 (7), 920-930, 2012 | 122 | 2012 |
