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| The NLRP3 inflammasome: a sensor for metabolic danger? K Schroder, R Zhou, J Tschopp Science 327 (5963), 296, 2010 | 1219 | 2010 |
| The regulated retrotransposon transcriptome of mammalian cells GJ Faulkner, Y Kimura, CO Daub, S Wani, C Plessy, KM Irvine, ... Nature genetics 41 (5), 563-571, 2009 | 888 | 2009 |
| NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice AR Mridha, A Wree, AAB Robertson, MM Yeh, CD Johnson, ... Journal of hepatology 66 (5), 1037-1046, 2017 | 861 | 2017 |
| Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and in vivo MK Chang, LJ Raggatt, KA Alexander, JS Kuliwaba, NL Fazzalari, ... The Journal of Immunology 181 (2), 1232-1244, 2008 | 743 | 2008 |
| MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition RC Coll, JR Hill, CJ Day, A Zamoshnikova, D Boucher, NL Massey, ... Nature chemical biology 15 (6), 556-559, 2019 | 651 | 2019 |
| Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice R Gordon, EA Albornoz, DC Christie, MR Langley, V Kumar, S Mantovani, ... Science translational medicine 10 (465), eaah4066, 2018 | 572 | 2018 |
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| AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC V Sagulenko, SJ Thygesen, DP Sester, A Idris, JA Cridland, PR Vajjhala, ... Cell Death & Differentiation 20 (9), 1149-1160, 2013 | 492 | 2013 |
| Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps KW Chen, M Monteleone, D Boucher, G Sollberger, D Ramnath, ... Science immunology 3 (26), eaar6676, 2018 | 488 | 2018 |
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| The neutrophil NLRC4 inflammasome selectively promotes IL-1β maturation without pyroptosis during acute Salmonella challenge KW Chen, CJ Groß, FV Sotomayor, KJ Stacey, J Tschopp, MJ Sweet, ... Cell reports 8 (2), 570-582, 2014 | 418 | 2014 |
| The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line Nature genetics 41 (5), 553-562, 2009 | 418 | 2009 |
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