| Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions N Tomimatsu, B Mukherjee, K Deland, A Kurimasa, E Bolderson, ... DNA repair 11 (4), 441-448, 2012 | 157 | 2012 |
| Dual-energy CT imaging of tumor liposome delivery after gold nanoparticle-augmented radiation therapy JR Ashton, KD Castle, Y Qi, DG Kirsch, JL West, CT Badea Theranostics 8 (7), 1782, 2018 | 95 | 2018 |
| Tumor cells, but not endothelial cells, mediate eradication of primary sarcomas by stereotactic body radiation therapy EJ Moding, KD Castle, BA Perez, P Oh, HD Min, H Norris, Y Ma, ... Science translational medicine 7 (278), 278ra34-278ra34, 2015 | 92 | 2015 |
| Atm deletion with dual recombinase technology preferentially radiosensitizes tumor endothelium EJ Moding, CL Lee, KD Castle, P Oh, L Mao, S Zha, HD Min, Y Ma, S Das, ... The Journal of clinical investigation 124 (8), 3325-3338, 2014 | 78 | 2014 |
| Establishing the impact of vascular damage on tumor response to high-dose radiation therapy KD Castle, DG Kirsch Cancer research 79 (22), 5685-5692, 2019 | 49 | 2019 |
| Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma CL Lee, KD Castle, EJ Moding, JM Blum, N Williams, L Luo, Y Ma, ... Nature communications 6 (1), 8477, 2015 | 47 | 2015 |
| Deletion of Atm in Tumor but not Endothelial Cells Improves Radiation Response in a Primary Mouse Model of Lung Adenocarcinoma JA Torok, P Oh, KD Castle, M Reinsvold, Y Ma, L Luo, CL Lee, DG Kirsch Cancer research 79 (4), 773-782, 2019 | 33 | 2019 |
| Genetically engineered mouse models for studying radiation biology KD Castle, M Chen, AJ Wisdom, DG Kirsch Translational cancer research 6 (Suppl 5), S900, 2017 | 31 | 2017 |
| Characterizing the potency and impact of carbon ion therapy in a primary mouse model of soft tissue sarcoma JM Brownstein, AJ Wisdom, KD Castle, YM Mowery, P Guida, CL Lee, ... Molecular cancer therapeutics 17 (4), 858-868, 2018 | 27 | 2018 |
| Inhibiting glycogen synthase kinase-3 mitigates the hematopoietic acute radiation syndrome in mice CL Lee, WE Lento, KD Castle, NJ Chao, DG Kirsch Radiation research 181 (5), 445-451, 2014 | 20 | 2014 |
| An extra copy of p53 suppresses development of spontaneous Kras-driven but not radiation-induced cancer EJ Moding, HD Min, KD Castle, M Ali, L Woodlief, N Williams, Y Ma, Y Kim, ... JCI insight 1 (10), 2016 | 14 | 2016 |
| Mice lacking RIP3 kinase are not protected from acute radiation syndrome KD Castle, AR Daniel, EJ Moding, L Luo, CL Lee, DG Kirsch Radiation research 189 (6), 627-633, 2018 | 6 | 2018 |
| Immune checkpoint inhibition and radiation therapy in 2 primary mouse models of soft tissue sarcoma: impact of tumor mutational load CL Kent, YM Mowery, AJ Wisdom, D Van Mater, KD Castle, A Reddy, ... International Journal of Radiation Oncology, Biology, Physics 96 (2), E578-E579, 2016 | 1 | 2016 |
| Using Genetically Engineered Mouse Models to Dissect the Critical Cellular Target of Radiation Therapy KD Castle Duke University, 2018 | | 2018 |
| Modulation of Endothelial Cell Radiation Sensitivity and Lung Tumor Response to Radiation Therapy J Torok, KD Castle, M Reinsvold, DG Kirsch International Journal of Radiation Oncology, Biology, Physics 93 (3), E546, 2015 | | 2015 |
| Abstract LB-167: Tumor cells, but not endothelial cells, mediate the eradication of primary cancers by radiation therapy EJ Moding, CL Lee, KD Castle, P Oh, DG Kirsch Cancer Research 74 (19_Supplement), LB-167-LB-167, 2014 | | 2014 |
| Using Mouse Genetics to Dissect the Radiobiology of SBRT: Tumor Cells, Not Endothelial Cells, Regulate Local Control E Moding, C Lee, KD Castle, P Oh, DG Kirsch International Journal of Radiation Oncology, Biology, Physics 90 (1), S56, 2014 | | 2014 |
| Dual Recombinase Technology Defines a Therapeutic Window for ATM Inhibitors to Selectively Radiosensitize Tumors E Moding, C Lee, KD Castle, P Oh, DG Kirsch International Journal of Radiation Oncology, Biology, Physics 90 (1), S35, 2014 | | 2014 |
| Improving the Effectiveness of Proton Therapy With Nanomedicine Y. Zheng, RF Fernando, 2 D. Maples, 2 and A. Ranjan2; 1Procure Proton Therapy Center, Oklahoma City, OK … J Torok, KD Castle, M Reinsvold, DG Kirsch | | |
