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Dr. Laxman Devkota
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Design, synthesis, and biological evaluation of water-soluble amino acid prodrug conjugates derived from combretastatin, dihydronaphthalene, and benzosuberene-based parent …
L Devkota, CM Lin, TE Strecker, Y Wang, JK Tidmore, Z Chen, ...
Bioorganic & medicinal chemistry 24 (5), 938-956, 2016
432016
Synthesis of structurally diverse benzosuberene analogues and their biological evaluation as anti-cancer agents
RP Tanpure, CS George, TE Strecker, L Devkota, JK Tidmore, CM Lin, ...
Bioorganic & medicinal chemistry 21 (24), 8019-8032, 2013
402013
Detection of response to tumor microenvironment–targeted cellular immunotherapy using nano-radiomics
L Devkota, Z Starosolski, CH Rivas, I Stupin, A Annapragada, ...
Science advances 6 (28), eaba6156, 2020
292020
Structural interrogation of benzosuberene-based inhibitors of tubulin polymerization
CA Herdman, L Devkota, CM Lin, H Niu, TE Strecker, R Lopez, L Liu, ...
Bioorganic & medicinal chemistry 23 (24), 7497-7520, 2015
292015
Nanoparticle contrast-enhanced T1-mapping enables estimation of placental fractional blood volume in a pregnant mouse model
AA Badachhape, L Devkota, IV Stupin, P Sarkar, M Srivastava, ...
Scientific reports 9 (1), 18707, 2019
192019
Pre-clinical magnetic resonance imaging of retroplacental clear space throughout gestation
AA Badachhape, A Kumar, KB Ghaghada, IV Stupin, M Srivastava, ...
Placenta 77, 1-7, 2019
172019
Bioreductively activatable prodrug conjugates of combretastatin A-1 and combretastatin A-4 as anticancer agents targeted toward tumor-associated hypoxia
BA Winn, L Devkota, B Kuch, MT MacDonough, TE Strecker, Y Wang, ...
Journal of natural products 83 (4), 937-954, 2020
152020
Pre-clinical dose-ranging efficacy, pharmacokinetics, tissue biodistribution, and toxicity of a targeted contrast agent for MRI of amyloid deposition in Alzheimer’s disease
AA Badachhape, PK Working, M Srivastava, P Bhandari, IV Stupin, ...
Scientific Reports 10 (1), 16185, 2020
142020
A Hyperfluorinated Hydrophilic Molecule for Aqueous 19F MRI Contrast Media
EA Tanifum, L Devkota, C Ngwa, AA Badachhape, KB Ghaghada, ...
Contrast Media & Molecular Imaging 2018, 2018
92018
A novel MRI contrast agent for identifying hyperphosphorylative neurons as a marker of future tau pathology: Neuroimaging: Novel imaging methods
A Badachhape, PA Parekh, Q Mu, R Bhavane, M Srivastava, I Stupin, ...
Alzheimer's & Dementia 16, e041080, 2020
52020
A surrogate marker for very early-stage tau pathology is detectable by molecular magnetic resonance imaging
P Parekh, Q Mu, A Badachhape, R Bhavane, M Srivastava, L Devkota, ...
Theranostics 12 (12), 5504, 2022
32022
Early detection of aortic degeneration in a mouse model of sporadic aortic aneurysm and dissection using nanoparticle contrast-enhanced computed tomography
KB Ghaghada, P Ren, L Devkota, Z Starosolski, C Zhang, D Vela, ...
Arteriosclerosis, thrombosis, and vascular biology 41 (4), 1534-1548, 2021
32021
Nanoparticle Contrast-enhanced MRI for Visualization of Retroplacental Clear Space Disruption in a Mouse Model of Placental Accreta Spectrum (PAS)
AA Badachhape, P Bhandari, L Devkota, M Srivastava, EA Tanifum, ...
Academic Radiology 30 (7), 1384-1391, 2023
22023
Identification of Sulfur Compounds in Petroleum Samples Using Derivatization with Mass Deficent Reagents
T Wang, D Jupiter, L Devkota, CK Chambliss, K Pinney, T Solouki
Proceedings of the 61st Annual American Society for Mass Spectrometry …, 2013
22013
PEGylated liposomal doxorubicin improves oral cancer response to radio-immunotherapy
L Devkota, R Bhavane, A Badachhape, R Veeramachaneni, R Menon, ...
Cancer Research 83 (7_Sup), 5174, 2023
12023
Multi-modal Imaging of Disease Progression in TH-MYCN Mouse Models of Neuroblastoma
AA Badachhape, L Tao, S Joshi, Z Starosolski, L Devkota, P Sarkar, ...
bioRxiv, 2022.03. 21.484628, 2022
12022
Early Detection of Tau Pathology
P Parekh, A Badachhape, Q Mu, R Bhavane, M Srivastava, L Devkota, ...
bioRxiv, 2021.05. 14.444233, 2021
12021
Targeting tumor hypoxia with prodrug conjugates of potent small-molecule inhibitors of tubulin polymerization
KG Pinney, ML Trawick, RP Mason, L Liu, DJ Chaplin, BA Winn, ...
Cancer Research 77 (13_Supplement), 3203-3203, 2017
12017
Design, synthesis, and biological evaluation of tumor-selective vascular disrupting agents, water-soluble amino acid prodrug conjugates, and bioreductively activatable prodrug …
L Devkota
12015
Molecular MRI Identifies Sexually Dimorphic AD Pathology in 3x Tg‐AD Mice
PA Parekh, AA Badachhape, R Menon, R Bhavane, M Srivastava, X Sun, ...
Alzheimer's & Dementia 19, e077269, 2023
2023
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