Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders C Binda, P Newton-Vinson, F Hubálek, DE Edmondson, A Mattevi Nature structural biology 9 (1), 22-26, 2002 | 805 | 2002 |
Three-dimensional structure of human monoamine oxidase A (MAO A): relation to the structures of rat MAO A and human MAO B L De Colibus, M Li, C Binda, A Lustig, DE Edmondson, A Mattevi Proceedings of the National Academy of Sciences 102 (36), 12684-12689, 2005 | 614 | 2005 |
Structures of human monoamine oxidase B complexes with selective noncovalent inhibitors: safinamide and coumarin analogs C Binda, J Wang, L Pisani, C Caccia, A Carotti, P Salvati, DE Edmondson, ... Journal of medicinal chemistry 50 (23), 5848-5852, 2007 | 594 | 2007 |
Insights into the mode of inhibition of human mitochondrial monoamine oxidase B from high-resolution crystal structures C Binda, M Li, F Hubálek, N Restelli, DE Edmondson, A Mattevi Proceedings of the National Academy of Sciences 100 (17), 9750-9755, 2003 | 504 | 2003 |
Structure and mechanism of monoamine oxidase DE Edmondson, A Mattevi, C Binda, M Li, F Hubalek Current medicinal chemistry 11 (15), 1983-1993, 2004 | 491 | 2004 |
A novel mammalian flavin-dependent histone demethylase A Karytinos, F Forneris, A Profumo, G Ciossani, E Battaglioli, C Binda, ... Journal of Biological Chemistry 284 (26), 17775-17782, 2009 | 359 | 2009 |
Molecular and mechanistic properties of the membrane-bound mitochondrial monoamine oxidases DE Edmondson, C Binda, J Wang, AK Upadhyay, A Mattevi Biochemistry 48 (20), 4220-4230, 2009 | 359 | 2009 |
Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2 C Binda, S Valente, M Romanenghi, S Pilotto, R Cirilli, A Karytinos, ... Journal of the American Chemical Society 132 (19), 6827-6833, 2010 | 350 | 2010 |
Histone demethylation catalysed by LSD1 is a flavin-dependent oxidative process F Forneris, C Binda, MA Vanoni, A Mattevi, E Battaglioli FEBS letters 579 (10), 2203-2207, 2005 | 334 | 2005 |
Structural basis of LSD1-CoREST selectivity in histone H3 recognition F Forneris, C Binda, A Adamo, E Battaglioli, A Mattevi Journal of Biological Chemistry 282 (28), 20070-20074, 2007 | 327 | 2007 |
Human histone demethylase LSD1 reads the histone code F Forneris, C Binda, MA Vanoni, E Battaglioli, A Mattevi Journal of Biological Chemistry 280 (50), 41360-41365, 2005 | 314 | 2005 |
Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors F Hubálek, C Binda, A Khalil, M Li, A Mattevi, N Castagnoli, ... Journal of biological chemistry 280 (16), 15761-15766, 2005 | 266 | 2005 |
Crystal structures of monoamine oxidase B in complex with four inhibitors of the N-propargylaminoindan class C Binda, F Hubálek, M Li, Y Herzig, J Sterling, DE Edmondson, A Mattevi Journal of medicinal chemistry 47 (7), 1767-1774, 2004 | 256 | 2004 |
Structural insights into the mechanism of amine oxidation by monoamine oxidases A and B DE Edmondson, C Binda, A Mattevi Archives of biochemistry and biophysics 464 (2), 269-276, 2007 | 250 | 2007 |
Structure-function relationships in flavoenzyme-dependent amine oxidations: a comparison of polyamine oxidase and monoamine oxidase C Binda, A Mattevi, DE Edmondson Journal of biological chemistry 277 (27), 23973-23976, 2002 | 248 | 2002 |
A 30 Å long U-shaped catalytic tunnel in the crystal structure of polyamine oxidase C Binda, A Coda, R Angelini, R Federico, P Ascenzi, A Mattevi Structure 7 (3), 265-276, 1999 | 224 | 1999 |
Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis J Neres, F Pojer, E Molteni, LR Chiarelli, N Dhar, S Boy-Röttger, S Buroni, ... Science translational medicine 4 (150), 150ra121-150ra121, 2012 | 217 | 2012 |
LSD1: oxidative chemistry for multifaceted functions in chromatin regulation F Forneris, C Binda, E Battaglioli, A Mattevi Trends in biochemical sciences 33 (4), 181-189, 2008 | 214 | 2008 |
Alternative splicing of the histone demethylase LSD1/KDM1 contributes to the modulation of neurite morphogenesis in the mammalian nervous system C Zibetti, A Adamo, C Binda, F Forneris, E Toffolo, C Verpelli, E Ginelli, ... Journal of Neuroscience 30 (7), 2521-2532, 2010 | 193 | 2010 |
Functional Role of the “Aromatic Cage” in Human Monoamine Oxidase B: Structures and Catalytic Properties of Tyr435 Mutant Proteins, M Li, C Binda, A Mattevi, DE Edmondson Biochemistry 45 (15), 4775-4784, 2006 | 172 | 2006 |