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Andrew J. Lucke
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Orally absorbed cyclic peptides
DS Nielsen, NE Shepherd, W Xu, AJ Lucke, MJ Stoermer, DP Fairlie
Chemical reviews 117 (12), 8094-8128, 2017
3612017
Potent antimalarial activity of histone deacetylase inhibitor analogues
KT Andrews, TN Tran, AJ Lucke, P Kahnberg, GT Le, GM Boyle, ...
Antimicrobial agents and chemotherapy 52 (4), 1454-1461, 2008
1532008
Improving on nature: making a cyclic heptapeptide orally bioavailable
DS Nielsen, HN Hoang, RJ Lohman, TA Hill, AJ Lucke, DJ Craik, ...
Angewandte Chemie International Edition 53 (45), 12059-12063, 2014
1502014
Antimalarial activity of the anticancer histone deacetylase inhibitor SB939
SDM Sumanadasa, CD Goodman, AJ Lucke, T Skinner-Adams, I Sahama, ...
Antimicrobial agents and chemotherapy 56 (7), 3849-3856, 2012
932012
Inhibitors of histone deacetylases in class I and class II suppress human osteoclasts in vitro
MD Cantley, DP Fairlie, PM Bartold, KD Rainsford, GT Le, AJ Lucke, ...
Journal of cellular physiology 226 (12), 3233-3241, 2011
932011
Histone deacetylase inhibitors and periodontal bone loss
MD Cantley, PM Bartold, V Marino, DP Fairlie, GT Le, AJ Lucke, ...
Journal of periodontal research 46 (6), 697-703, 2011
882011
Design, synthesis, potency, and cytoselectivity of anticancer agents derived by parallel synthesis from α-aminosuberic acid
P Kahnberg, AJ Lucke, MP Glenn, GM Boyle, JDA Tyndall, PG Parsons, ...
Journal of medicinal chemistry 49 (26), 7611-7622, 2006
802006
Comparing sixteen scoring functions for predicting biological activities of ligands for protein targets
W Xu, AJ Lucke, DP Fairlie
Journal of Molecular Graphics and Modelling 57, 76-88, 2015
752015
Flexibility versus rigidity for orally bioavailable cyclic hexapeptides
DS Nielsen, RJ Lohman, HN Hoang, TA Hill, A Jones, AJ Lucke, ...
ChemBioChem 16 (16), 2289-2293, 2015
702015
Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed
TA Hill, RJ Lohman, HN Hoang, DS Nielsen, CCG Scully, WM Kok, L Liu, ...
ACS medicinal chemistry letters 5 (10), 1148-1151, 2014
652014
Antimalarial histone deacetylase inhibitors containing cinnamate or NSAID components
NC Wheatley, KT Andrews, TL Tran, AJ Lucke, RC Reid, DP Fairlie
Bioorganic & medicinal chemistry letters 20 (23), 7080-7084, 2010
632010
Designing supramolecular structures from models of cyclic peptide scaffolds with heterocyclic constraints
AJ Lucke, JDA Tyndall, Y Singh, DP Fairlie
Journal of Molecular Graphics and Modelling 21 (5), 341-355, 2003
502003
Thin films of calix-4-resorcinarene deposited by spin coating and Langmuir–Blodgett techniques: determination of film parameters by surface plasmon resonance
AK Hassan, AV Nabok, AK Ray, A Lucke, K Smith, CJM Stirling, F Davis
Materials Science and Engineering: C 8, 251-255, 1999
471999
Inhibitors selective for HDAC6 in enzymes and cells
PK Gupta, RC Reid, L Liu, AJ Lucke, SA Broomfield, MR Andrews, ...
Bioorganic & medicinal chemistry letters 20 (23), 7067-7070, 2010
442010
Structural Mimicry of Two Cytochrome b562 Interhelical Loops Using Macrocycles Constrained by Oxazoles and Thiazoles
Y Singh, MJ Stoermer, AJ Lucke, T Guthrie, DP Fairlie
Journal of the American Chemical Society 127 (18), 6563-6572, 2005
442005
The electrochemistry of the ferri/ferrocyanide couple at a calix [4] resorcinarenetetrathiol-modified gold electrode as a study of novel electrode modifying coatings for use …
SD Collyer, F Davis, A Lucke, CJM Stirling, SPJ Higson
Journal of Electroanalytical Chemistry 549, 119-127, 2003
432003
Regioselective synthesis of antiparallel loops on a macrocyclic scaffold constrained by oxazoles and thiazoles
Y Singh, MJ Stoermer, AJ Lucke, MP Glenn, DP Fairlie
Organic Letters 4 (20), 3367-3370, 2002
352002
Order and Structure in Langmuir− Blodgett Mono-and Multilayers of Resorcarenes
F Davis, AJ Lucke, KA Smith, CJM Stirling
Langmuir 14 (15), 4180-4185, 1998
341998
Amyloid Formation from an α‐Helix Peptide Bundle Is Seeded by 310‐Helix Aggregates
Y Singh, PC Sharpe, HN Hoang, AJ Lucke, AW McDowall, SP Bottomley, ...
Chemistry–A European Journal 17 (1), 151-160, 2011
332011
Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasis
SH Kim, RP Redvers, LH Chi, X Ling, AJ Lucke, RC Reid, DP Fairlie, ...
Disease models & mechanisms 11 (7), DMM034850, 2018
302018
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Articles 1–20