|Durvalumab with or without tremelimumab vs standard chemotherapy in first-line treatment of metastatic non–small cell lung cancer: the MYSTIC phase 3 randomized clinical trial|
NA Rizvi, BC Cho, N Reinmuth, KH Lee, A Luft, MJ Ahn, ...
JAMA oncology 6 (5), 661-674, 2020
|Tremelimumab as second-line or third-line treatment in relapsed malignant mesothelioma (DETERMINE): a multicentre, international, randomised, double-blind, placebo-controlled …|
M Maio, A Scherpereel, L Calabrò, J Aerts, SC Perez, A Bearz, ...
The Lancet Oncology 18 (9), 1261-1273, 2017
|Vandetanib versus gefitinib in patients with advanced non–small-cell lung cancer: results from a two-part, double-blind, randomized phase II study|
RB Natale, D Bodkin, R Govindan, BG Sleckman, NA Rizvi, A Capó, ...
Journal of Clinical Oncology 27 (15), 2523-2529, 2009
|A randomized, open-label study of the efficacy and safety of AZD4547 monotherapy versus paclitaxel for the treatment of advanced gastric adenocarcinoma with FGFR2 polysomy or …|
E Van Cutsem, YJ Bang, W Mansoor, RD Petty, Y Chao, D Cunningham, ...
Annals of Oncology 28 (6), 1316-1324, 2017
|ZD6474 versus gefitinib in patients with advanced NSCLC: Final results from a two-part, double-blind, randomized phase II trial|
RB Natale, D Bodkin, R Govindan, B Sleckman, N Rizvi, A Capo, ...
Journal of Clinical Oncology 24 (18_suppl), 7000-7000, 2006
|Phase 1/2 study to assess the safety, efficacy, and pharmacokinetics of barasertib (AZD1152) in patients with advanced acute myeloid leukemia|
B Löwenberg, P Muus, G Ossenkoppele, P Rousselot, JY Cahn, N Ifrah, ...
Blood, The Journal of the American Society of Hematology 118 (23), 6030-6036, 2011
|Clinical evaluation of AZD1152, an iv inhibitor of Aurora B kinase, in patients with solid malignant tumors|
DS Boss, PO Witteveen, J Van Der Sar, MP Lolkema, EE Voest, ...
Annals of Oncology 22 (2), 431-437, 2011
|Durvalumab with or without tremelimumab vs platinum-based chemotherapy as first-line treatment for metastatic non-small cell lung cancer: MYSTIC|
NA Rizvi, BC Cho, N Reinmuth, KH Lee, MJ Ahn, A Luft, ...
Annals of Oncology 29, x40-x41, 2018
|Stage I of a phase 2 study assessing the efficacy, safety, and tolerability of barasertib (AZD1152) versus low‐dose cytosine arabinoside in elderly patients with acute myeloid …|
HM Kantarjian, G Martinelli, EJ Jabbour, A Quintás‐Cardama, K Ando, ...
Cancer 119 (14), 2611-2619, 2013
|ARCTIC: durvalumab with or without tremelimumab as third-line or later treatment of metastatic non-small-cell lung cancer|
D Planchard, N Reinmuth, S Orlov, JR Fischer, S Sugawara, S Mandziuk, ...
Annals of Oncology 31 (5), 609-618, 2020
|Identification of a basic hybrid glutathione S-transferase from human liver. Glutathione S-transferase δ is composed of two distinct subunits (B1 and B2)|
PK Stockman, GJ Beckett, JD Hayes
Biochemical Journal 227 (2), 457-465, 1985
|Phase I study of barasertib (AZD1152), a selective inhibitor of Aurora B kinase, in patients with advanced solid tumors|
GK Schwartz, RD Carvajal, R Midgley, SJ Rodig, PK Stockman, O Ataman, ...
Investigational new drugs 31, 370-380, 2013
|Variations in the glutathione S-transferase subunits expressed in human livers|
AJ Hussey, PK Stockman, GJ Beckett, JD Hayes
Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1986
|Phase I study of the Aurora B kinase inhibitor barasertib (AZD1152) to assess the pharmacokinetics, metabolism and excretion in patients with acute myeloid leukemia|
M Dennis, M Davies, S Oliver, R D’Souza, L Pike, P Stockman
Cancer chemotherapy and pharmacology 70, 461-469, 2012
|Phase I study assessing the safety and tolerability of barasertib (AZD1152) with low-dose cytosine arabinoside in elderly patients with AML|
HM Kantarjian, MA Sekeres, V Ribrag, P Rousselot, G Garcia-Manero, ...
Clinical Lymphoma Myeloma and Leukemia 13 (5), 559-567, 2013
|Abstract LB-145: Results of a phase I study of AZD4547, an inhibitor of fibroblast growth factor receptor (FGFR), in patients with advanced solid tumors.|
F Andre, M Ranson, E Dean, A Varga, R Van der Noll, PK Stockman, ...
Cancer research 73 (8_Supplement), LB-145-LB-145, 2013
|Characterization of the basic glutathione S-transferase B1 and B2 subunits from human liver|
PK Stockman, LI McLELLAN, JD Hayes
Biochemical Journal 244 (1), 55-61, 1987
|A randomized, open-label phase II study of AZD4547 (AZD) versus Paclitaxel (P) in previously treated patients with advanced gastric cancer (AGC) with Fibroblast Growth Factor …|
YJ Bang, E Van Cutsem, W Mansoor, RD Petty, Y Chao, D Cunningham, ...
Journal of Clinical Oncology 33 (15_suppl), 4014-4014, 2015
|Tremelimumab as second-or third-line treatment of unresectable malignant mesothelioma (MM): Results from the global, double-blind, placebo-controlled DETERMINE study.|
HL Kindler, A Scherpereel, L Calabrò, J Aerts, S Cedres Perez, A Bearz, ...
Journal of Clinical Oncology 34 (15_suppl), 8502-8502, 2016
|ACCELERATE and European Medicines Agency Paediatric Strategy Forum for medicinal product development of checkpoint inhibitors for use in combination therapy in paediatric patients|
ADJ Pearson, C Rossig, G Lesa, SJ Diede, S Weiner, J Anderson, J Gray, ...
European Journal of Cancer 127, 52-66, 2020