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Alexander Chumanevich
Alexander Chumanevich
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Year
Resveratrol suppresses colitis and colon cancer associated with colitis
X Cui, Y Jin, AB Hofseth, E Pena, J Habiger, A Chumanevich, D Poudyal, ...
Cancer prevention research 3 (4), 549-559, 2010
2402010
Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor
AA Chumanevich, CP Causey, BA Knuckley, JE Jones, D Poudyal, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 300 (6 …, 2011
2172011
Chronic epithelial NF-κB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation
H Shaked, LJ Hofseth, A Chumanevich, AA Chumanevich, J Wang, ...
Proceedings of the National Academy of Sciences 109 (35), 14007-14012, 2012
1632012
Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer
MSJ McDermott, AA Chumanevich, C Lim, J Liang, M Chen, S Altilia, ...
Oncotarget 8 (8), 12558, 2017
1262017
Ginkgo biloba extract EGb 761 has anti-inflammatory properties and ameliorates colitis in mice by driving effector T cell apoptosis
VS Kotakadi, Y Jin, AB Hofseth, L Ying, X Cui, S Volate, A Chumanevich, ...
Carcinogenesis 29 (9), 1799-1806, 2008
1202008
Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinase
AA Chumanevich, D Poudyal, X Cui, T Davis, PA Wood, CD Smith, ...
Carcinogenesis 31 (10), 1787-1793, 2010
1112010
Seeing citrulline: development of a phenylglyoxal-based probe to visualize protein citrullination
KL Bicker, V Subramanian, AA Chumanevich, LJ Hofseth, PR Thompson
Journal of the American Chemical Society 134 (41), 17015-17018, 2012
1102012
The development of N-α-(2-carboxyl) benzoyl-N 5-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-α-(2-carboxyl) benzoyl-N 5-(2-chloro-1-iminoethyl)-l-ornithine …
CP Causey, JE Jones, JL Slack, D Kamei, LE Jones Jr, V Subramanian, ...
Journal of medicinal chemistry 54 (19), 6919-6935, 2011
922011
The development of N-α-(2-carboxyl) benzoyl-N 5-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-α-(2-carboxyl) benzoyl-N 5-(2-chloro-1-iminoethyl)-l-ornithine …
CP Causey, JE Jones, JL Slack, D Kamei, LE Jones Jr, V Subramanian, ...
Journal of medicinal chemistry 54 (19), 6919-6935, 2011
922011
Adiponectin deficiency: role in chronic inflammation induced colon cancer
A Saxena, A Chumanevich, E Fletcher, B Larsen, K Lattwein, K Kaur, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (4), 527-536, 2012
912012
CDK8 selectively promotes the growth of colon cancer metastases in the liver by regulating gene expression of TIMP3 and matrix metalloproteinases
J Liang, M Chen, D Hughes, AA Chumanevich, S Altilia, V Kaza, CU Lim, ...
Cancer research 78 (23), 6594-6606, 2018
842018
Biochemical and structural analysis of substrate promiscuity in plant Mg2+-dependent O-methyltransferases
JG Kopycki, D Rauh, AA Chumanevich, P Neumann, T Vogt, MT Stubbs
Journal of molecular biology 378 (1), 154-164, 2008
722008
Caught in the act: the 1.5 Å resolution crystal structures of the HIV-1 protease and the I54V mutant reveal a tetrahedral reaction intermediate
AY Kovalevsky, AA Chumanevich, F Liu, JM Louis, IT Weber
Biochemistry 46 (51), 14854-14864, 2007
592007
Mediator kinase CDK8/CDK19 drives YAP1-dependent BMP4-induced EMT in cancer
A Serrao, LM Jenkins, AA Chumanevich, B Horst, J Liang, ML Gatza, ...
Oncogene 37 (35), 4792-4808, 2018
572018
Systemic inflammatory load in humans is suppressed by consumption of two formulations of dried, encapsulated juice concentrate
Y Jin, X Cui, UP Singh, AA Chumanevich, B Harmon, P Cavicchia, ...
Molecular nutrition & food research 54 (10), 1506-1514, 2010
562010
The induction of microRNA-16 in colon cancer cells by protein arginine deiminase inhibition causes a p53-dependent cell cycle arrest
X Cui, EE Witalison, AP Chumanevich, AA Chumanevich, D Poudyal, ...
PloS one 8 (1), e53791, 2013
532013
d-Amino Acid-Based Protein Arginine Deiminase Inhibitors: Synthesis, Pharmacokinetics, and in Cellulo Efficacy
KL Bicker, L Anguish, AA Chumanevich, MD Cameron, X Cui, E Witalison, ...
ACS medicinal chemistry letters 3 (12), 1081-1085, 2012
502012
Antibiotic‐mediated bacteriome depletion in ApcMin/+ mice is associated with reduction in mucus‐producing goblet cells and increased colorectal cancer …
K Kaur, A Saxena, I Debnath, JL O'Brien, NJ Ajami, TA Auchtung, ...
Cancer medicine 7 (5), 2003-2012, 2018
462018
Design, synthesis, protein− ligand X-ray structure, and biological evaluation of a series of novel macrocyclic human immunodeficiency virus-1 protease inhibitors to combat drug …
AK Ghosh, S Kulkarni, DD Anderson, L Hong, A Baldridge, YF Wang, ...
Journal of medicinal chemistry 52 (23), 7689-7705, 2009
452009
A hexane fraction of American ginseng suppresses mouse colitis and associated colon cancer: anti-inflammatory and proapoptotic mechanisms
D Poudyal, P Mai Le, T Davis, AB Hofseth, A Chumanevich, ...
Cancer Prevention Research 5 (4), 685-696, 2012
432012
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