Cell migration: a physically integrated molecular process DA Lauffenburger, AF Horwitz cell 84 (3), 359-369, 1996 | 5249 | 1996 |
Causal protein-signaling networks derived from multiparameter single-cell data K Sachs, O Perez, D Pe'er, DA Lauffenburger, GP Nolan Science 308 (5721), 523-529, 2005 | 2226 | 2005 |
Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness SP Palecek, JC Loftus, MH Ginsberg, DA Lauffenburger, AF Horwitz Nature 385 (6616), 537-540, 1997 | 1785 | 1997 |
Receptors: models for binding, trafficking, and signaling DA Lauffenburger, JJ Linderman Oxford University Press, USA, 1996 | 1467 | 1996 |
Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis MH Zaman, LM Trapani, AL Sieminski, D MacKellar, H Gong, RD Kamm, ... Proceedings of the National Academy of Sciences 103 (29), 10889-10894, 2006 | 1446 | 2006 |
Cell adhesion and motility depend on nanoscale RGD clustering G Maheshwari, G Brown, DA Lauffenburger, A Wells, LG Griffith Journal of cell science 113 (10), 1677-1686, 2000 | 1211 | 2000 |
Mathematical model for the effects of adhesion and mechanics on cell migration speed PA DiMilla, K Barbee, DA Lauffenburger Biophysical journal 60 (1), 15-37, 1991 | 794 | 1991 |
Maximal migration of human smooth muscle cells on fibronectin and type IV collagen occurs at an intermediate attachment strength PA DiMilla, JA Stone, JA Quinn, SM Albelda, DA Lauffenburger The Journal of cell biology 122 (3), 729-737, 1993 | 789 | 1993 |
Physicochemical modelling of cell signalling pathways BB Aldridge, JM Burke, DA Lauffenburger, PK Sorger Nature cell biology 8 (11), 1195-1203, 2006 | 778 | 2006 |
Vector unpacking as a potential barrier for receptor‐mediated polyplex gene delivery DV Schaffer, NA Fidelman, N Dan, DA Lauffenburger Biotechnology and bioengineering 67 (5), 598-606, 2000 | 675 | 2000 |
A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis KA Janes, JG Albeck, S Gaudet, PK Sorger, DA Lauffenburger, MB Yaffe Science 310 (5754), 1646-1653, 2005 | 641 | 2005 |
Time-resolved Mass Spectrometry of Tyrosine Phosphorylation Sites in the Epidermal Growth Factor Receptor Signaling Network Reveals Dynamic Modules* S Y Zhang, A Wolf-Yadlin, PL Ross, DJ Pappin, J Rush, DA Lauffenburger, ... Molecular & Cellular Proteomics 4 (9), 1240-1250, 2005 | 626 | 2005 |
Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks A Wolf-Yadlin, S Hautaniemi, DA Lauffenburger, FM White Proceedings of the National Academy of Sciences 104 (14), 5860-5865, 2007 | 596 | 2007 |
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses KD Moynihan, CF Opel, GL Szeto, A Tzeng, EF Zhu, JM Engreitz, ... Nature medicine 22 (12), 1402-1410, 2016 | 563 | 2016 |
A functional role for antibodies in tuberculosis LL Lu, AW Chung, TR Rosebrock, M Ghebremichael, WH Yu, PS Grace, ... Cell 167 (2), 433-443. e14, 2016 | 560 | 2016 |
Co-regulation of cell adhesion by nanoscale RGD organization and mechanical stimulus LY Koo, DJ Irvine, AM Mayes, DA Lauffenburger, LG Griffith Journal of cell science 115 (7), 1423-1433, 2002 | 530 | 2002 |
Microfluidic shear devices for quantitative analysis of cell adhesion H Lu, LY Koo, WM Wang, DA Lauffenburger, LG Griffith, KF Jensen Analytical chemistry 76 (18), 5257-5264, 2004 | 514 | 2004 |
Cutting to the chase: calpain proteases in cell motility A Glading, DA Lauffenburger, A Wells Trends in cell biology 12 (1), 46-54, 2002 | 493 | 2002 |
Regulation of cell migration by the calcium-dependent protease calpain A Huttenlocher, SP Palecek, Q Lu, W Zhang, RL Mellgren, ... Journal of Biological Chemistry 272 (52), 32719-32722, 1997 | 488 | 1997 |
Cancer systems biology: a network modeling perspective PK Kreeger, DA Lauffenburger Carcinogenesis 31 (1), 2-8, 2010 | 478 | 2010 |