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Jorge Alex Pavon
Jorge Alex Pavon
Verified email at merck.com
Title
Cited by
Cited by
Year
Insights into the catalytic mechanisms of phenylalanine and tryptophan hydroxylase from kinetic isotope effects on aromatic hydroxylation
JA Pavon, PF Fitzpatrick
Biochemistry 45 (36), 11030-11037, 2006
572006
Analysis of monoclonal antibody oxidation by simple mixed mode chromatography
JA Pavon, X Li, S Chico, U Kishnani, S Soundararajan, J Cheung, H Li, ...
Journal of Chromatography A 1431, 154-165, 2016
392016
Kinetic mechanism of phenylalanine hydroxylase: Intrinsic binding and rate constants from single-turnover experiments
KM Roberts, JA Pavon, PF Fitzpatrick
Biochemistry 52 (6), 1062-1073, 2013
342013
Intrinsic isotope effects on benzylic hydroxylation by the aromatic amino acid hydroxylases: evidence for hydrogen tunneling, coupled motion, and similar reactivities
JA Pavon, PF Fitzpatrick
Journal of the American Chemical Society 127 (47), 16414-16415, 2005
342005
Identification and characterization of a residual host cell protein hexosaminidase B associated with N‐glycan degradation during the stability study of a therapeutic …
X Li, Y An, J Liao, L Xiao, M Swanson, K Martinez‐Fonts, JA Pavon, ...
Biotechnology progress 37 (3), e3128, 2021
262021
Single turnover kinetics of tryptophan hydroxylase: Evidence for a new intermediate in the reaction of the aromatic amino acid hydroxylases
JA Pavon, B Eser, MT Huynh, PF Fitzpatrick
Biochemistry 49 (35), 7563-7571, 2010
252010
Selective tryptophan oxidation of monoclonal antibodies: Oxidative stress and modeling prediction
JA Pavon, L Xiao, X Li, J Zhao, D Aldredge, E Dank, A Fridman, YH Liu
Analytical chemistry 91 (3), 2192-2200, 2019
182019
Demonstration of a peroxide shunt in the tetrahydropterin-dependent aromatic amino acid monooxygenases
JA Pavon, PF Fitzpatrick
Journal of the American Chemical Society 131 (13), 4582-4583, 2009
162009
Determination of ultra-trace metal-protein interactions in co-formulated monoclonal antibody drug product by SEC-ICP-MS
L Whitty-Léveillé, ZL VanAernum, JA Pavon, C Murphy, K Neal, W Forest, ...
Mabs 15 (1), 2199466, 2023
12023
MECHANISM OF OXYGEN ACTIVATION AND HYDROXYLATION BY THE AROMATIC AMINO ACID HYDROXYLASES
JA Pavon
Texas A & M University, 2010
2010
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