Seuraa
Miia Turpeinen
Miia Turpeinen
Vahvistettu sähköpostiosoite verkkotunnuksessa oulu.fi
Nimike
Viittaukset
Viittaukset
Vuosi
Membrane transporters in drug development
Nature reviews Drug discovery 9 (3), 215-236, 2010
34812010
Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation
UM Zanger, M Turpeinen, K Klein, M Schwab
Analytical and bioanalytical chemistry 392, 1093-1108, 2008
7302008
Inhibition and induction of human cytochrome P450 enzymes: current status
O Pelkonen, M Turpeinen, J Hakkola, P Honkakoski, J Hukkanen, ...
Archives of toxicology 82, 667-715, 2008
7022008
Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells
S Antherieu, C Chesne, R Li, S Camus, A Lahoz, L Picazo, M Turpeinen, ...
Drug Metabolism and Disposition 38 (3), 516-525, 2010
2852010
Inhibition and induction of CYP enzymes in humans: an update
J Hakkola, J Hukkanen, M Turpeinen, O Pelkonen
Archives of Toxicology 94 (11), 3671-3722, 2020
2322020
Prediction of Drug Metabolism and Interactions on the Basis of in vitro Investigations
O Pelkonen, M Turpeinen, J Uusitalo, A Rautio, H Raunio
Basic & clinical pharmacology & toxicology 96 (3), 167-175, 2005
1712005
Effect of clopidogrel and ticlopidine on cytochrome P450 2B6 activity as measured by bupropion hydroxylation
M Turpeinen, A Tolonen, J Uusitalo, J Jalonen, O Pelkonen, K Laine
Clinical Pharmacology & Therapeutics 77 (6), 553-559, 2005
1682005
Liquid chromatography–mass spectrometry in in vitro drug metabolite screening
A Tolonen, M Turpeinen, O Pelkonen
Drug discovery today 14 (3-4), 120-133, 2009
1662009
Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay
M Turpeinen, U Jouko, J Jorma, P Olavi
European journal of pharmaceutical sciences 24 (1), 123-132, 2005
1642005
Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay
M Turpeinen, U Jouko, J Jorma, P Olavi
European journal of pharmaceutical sciences 24 (1), 123-132, 2005
1642005
Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay
M Turpeinen, U Jouko, J Jorma, P Olavi
European journal of pharmaceutical sciences 24 (1), 123-132, 2005
1642005
The functional role of CYP2B6 in human drug metabolism: substrates and inhibitors in vitro, in vivo and in silico
M Turpeinen, H Raunio, O Pelkonen
Current drug metabolism 7 (7), 705-714, 2006
1582006
Pharmacogenomics of human liver cytochrome P450 oxidoreductase: multifactorial analysis and impact on microsomal drug oxidation
AM Gomes, S Winter, K Klein, M Turpeinen, E Schaeffeler, M Schwab, ...
Future Medicine Ltd 10 (4), 579-599, 2009
1502009
Selective inhibition of CYP2B6-catalyzed bupropion hydroxylation in human liver microsomes in vitro
M Turpeinen, R Nieminen, T Juntunen, P Taavitsainen, H Raunio, ...
Drug metabolism and disposition 32 (6), 626-631, 2004
1322004
CYP2B6 and CYP2C19 as the major enzymes responsible for the metabolism of selegiline, a drug used in the treatment of Parkinson's disease, as revealed from experiments with …
M Hidestrand, M Oscarson, JS Salonen, L Nyman, O Pelkonen, ...
Drug Metabolism and Disposition 29 (11), 1480-1484, 2001
1312001
Predictive value of animal models for human cytochrome P450 (CYP)-mediated metabolism: A comparative study in vitro
M Turpeinen, C Ghiciuc, M Opritoui, L Tursas, O Pelkonen, M Pasanen
Xenobiotica 37 (12), 1367-1377, 2007
1272007
In vitro–in vivo extrapolation of hepatic clearance: Biological tools, scaling factors, model assumptions and correct concentrations
O Pelkonen, M Turpeinen
Xenobiotica 37 (10-11), 1066-1089, 2007
1262007
Functional expression, inhibition and induction of CYP enzymes in HepaRG cells
M Turpeinen, A Tolonen, C Chesne, A Guillouzo, J Uusitalo, O Pelkonen
Toxicology in Vitro 23 (4), 748-753, 2009
1252009
Vildagliptin significantly increases the risk of bullous pemphigoid: a Finnish nationwide registry study
O Varpuluoma, AK Försti, J Jokelainen, M Turpeinen, M Timonen, ...
Elsevier, 2018
1162018
In vitro interaction cocktail assay for nine major cytochrome P450 enzymes with 13 probe reactions and a single LC/MSMS run: analytical validation and testing with …
A Tolonen, A Petsalo, M Turpeinen, J Uusitalo, O Pelkonen
Journal of mass spectrometry 42 (7), 960-966, 2007
1152007
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