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Paul Little
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Year
Myeloid-derived suppressor cells regulate T cell and B cell responses during autoimmune disease
KR Crook, M Jin, MF Weeks, RR Rampersad, RM Baldi, AS Glekas, ...
Journal of Leucocyte Biology 97 (3), 573-582, 2015
1122015
The association between copy number aberration, DNA methylation and gene expression in tumor samples
W Sun, P Bunn, C Jin, P Little, V Zhabotynsky, CM Perou, DN Hayes, ...
Nucleic acids research 46 (6), 3009-3018, 2018
602018
LCCC 1025: a phase II study of everolimus, trastuzumab, and vinorelbine to treat progressive HER2-positive breast cancer brain metastases
AED Van Swearingen, MB Siegel, AM Deal, MJ Sambade, A Hoyle, ...
Breast cancer research and treatment 171, 637-648, 2018
462018
The prognostic significance of low-frequency somatic mutations in metastatic cutaneous melanoma
X Zhao, P Little, AP Hoyle, GJ Pegna, MC Hayward, A Ivanova, JS Parker, ...
Frontiers in oncology 8, 584, 2019
192019
eQTL mapping using allele-specific count data is computationally feasible, powerful, and provides individual-specific estimates of genetic effects
V Zhabotynsky, L Huang, P Little, YJ Hu, F Pardo-Manuel de Villena, ...
PLoS genetics 18 (3), e1010076, 2022
152022
Correlation of alterations in the KEAP1/CUL3/NFE2L2 pathway with radiation failure in larynx squamous cell carcinoma
S Sheth, DR Farquhar, TP Schrank, W Stepp, A Mazul, M Hayward, ...
Laryngoscope investigative otolaryngology 6 (4), 699-707, 2021
112021
Associating somatic mutations to clinical outcomes: a pan-cancer study of survival time
P Little, DY Lin, W Sun
Genome medicine 11, 1-15, 2019
102019
Characterization of the number and site of APC mutations in sporadic colorectal cancer.
R Joseph, P Little, DN Hayes, MS Lee
Journal of Clinical Oncology 35 (4_suppl), 630-630, 2017
92017
UNMASC: tumor-only variant calling with unmatched normal controls
P Little, H Jo, A Hoyle, A Mazul, X Zhao, AH Salazar, D Farquhar, S Sheth, ...
NAR Cancer 3 (4), zcab040, 2021
62021
LCCC 1025: Phase II study of everolimus, trastuzumab, and vinorelbine for HER2+ breast cancer brain metastases (BCBM).
CK Anders, AM Deal, AED Van Swearingen, M Siegel, DN Hayes, H Jo, ...
Journal of Clinical Oncology 35 (15_suppl), 1011-1011, 2017
42017
Cell type-specific Expression Quantitative Trait Loci
P Little, V Zhabotynsky, Y Li, D Lin, W Sun
bioRxiv, 2022.03. 31.486605, 2022
22022
Genetic Mutations in KEAP/NFE2L2 Associated With Radiation Resistance in Early-Stage Laryngeal Squamous Cell Carcinoma: A Case Series
D Farquhar, S Sheth, A Mazul, P Little, DN Hayes, JP Zevallos
International Journal of Radiation Oncology• Biology• Physics 100 (5), 1375-1376, 2018
12018
A computational method for cell type-specific expression quantitative trait loci mapping using bulk RNA-seq data
P Little, S Liu, V Zhabotynsky, Y Li, DY Lin, W Sun
Nature Communications 14 (1), 3030, 2023
2023
Viral genome structure correlates with patterns of somatic alteration in human papillomavirus associated head and neck squamous cell carcinoma
JR Holt, X Zhao, HY Choi, P Little, AL Mazul, B Wahle, V Walter, ...
Cancer Research 83 (7_Supplement), 6062-6062, 2023
2023
Associating Somatic Mutation with Clinical Outcomes through Kernel Regression and Optimal Transport
P Little, L Hsu, W Sun
Biometrics, 2022
2022
Integrative genomic analysis of human papillomavirus associated head and neck squamous cell carcinoma reveals selective pressure for somatic alteration of E6 and E7 targets
J Holt, H Jo, X Zhao, HY Choi, V Walter, P Little, B Wahle, A Mazul, ...
Cancer Research 82 (12_Supplement), 49-49, 2022
2022
A Statistical Method for Association Analysis of Cell Type Compositions
L Huang, P Little, JR Huyghe, Q Shi, TA Harrison, G Yothers, TJ George, ...
Statistics in biosciences 13, 373-385, 2021
2021
Analysis of Somatic Mutation Data and Cell Type-Specific eQTL Mapping
PL Little
The University of North Carolina at Chapel Hill, 2019
2019
Statistical considerations in tumor only variant calling
P Little, DN Hayes, J Parker, J Zevallos
Cancer Research 77 (13_Supplement), 3584-3584, 2017
2017
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Articles 1–19