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David M. Shechner
David M. Shechner
Assistant Professor of Pharmacology, University of Washington
Vahvistettu sähköpostiosoite verkkotunnuksessa uw.edu - Kotisivu
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Vuosi
Multiplexable, locus-specific targeting of long RNAs with CRISPR-Display
DM Shechner, E Hacisuleyman, ST Younger, JL Rinn
Nature methods 12 (7), 664-670, 2015
3182015
Chromatin environment, transcriptional regulation, and splicing distinguish lincRNAs and mRNAs
M Melé, K Mattioli, W Mallard, DM Shechner, C Gerhardinger, JL Rinn
Genome research 27 (1), 27-37, 2017
2462017
Live-cell mapping of organelle-associated RNAs via proximity biotinylation combined with protein-RNA crosslinking
P Kaewsapsak, DM Shechner, W Mallard, JL Rinn, AY Ting
Elife 6, e29224, 2017
1652017
Crystal structure of the catalytic core of an RNA-polymerase ribozyme
DM Shechner, RA Grant, SC Bagby, Y Koldobskaya, JA Piccirilli, ...
Science 326 (5957), 1271-1275, 2009
1432009
Directed evolution of split APEX2 peroxidase
Y Han, TC Branon, JD Martell, D Boassa, D Shechner, MH Ellisman, ...
ACS Chemical Biology 14 (4), 619-635, 2019
1402019
High‐throughput identification of RNA nuclear enrichment sequences
CJ Shukla, AL McCorkindale, C Gerhardinger, KD Korthauer, MN Cabili, ...
The EMBO journal 37 (6), e98452, 2018
1092018
Spatiotemporal allele organization by allele-specific CRISPR live-cell imaging (SNP-CLING)
PG Maass, AR Barutcu, DM Shechner, CL Weiner, M Melé, JL Rinn
Nature structural & molecular biology 25 (2), 176-184, 2018
902018
A portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination
Y Koldobskaya, EM Duguid, DM Shechner, NB Suslov, J Ye, SS Sidhu, ...
Nature structural & molecular biology 18 (1), 100-106, 2011
832011
The structural basis of RNA-catalyzed RNA polymerization
DM Shechner, DP Bartel
Nature structural & molecular biology 18 (9), 1036-1042, 2011
532011
A class I ligase ribozyme with reduced Mg2+ dependence: Selection, sequence analysis, and identification of functional tertiary interactions
SC Bagby, NH Bergman, DM Shechner, C Yen, DP Bartel
Rna 15 (12), 2129-2146, 2009
252009
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo
DM Shechner, E Hacisüleyman, ST Younger, JL Rinn
Nature methods 12 (7), 664, 2015
102015
‘Morphs’(MRFs): metal-reversible folding domains for differential IgG binding
SF Marino, D Shechner, L Regan
Chemistry & biology 8 (12), 1221-1229, 2001
92001
Oligonucleotide-directed proximity-interactome mapping (O-MAP): A unified method for discovering RNA-interacting proteins, transcripts and genomic loci in situ
AF Tsue, EE Kania, DQ Lei, R Fields, CD McGann, E Hershberg, X Deng, ...
bioRxiv, 2023.01. 19.524825, 2023
52023
Methods of making and using guide RNA for use with Cas9 systems
JL Rinn, DM Shechner
US Patent 10,920,221, 2021
42021
High-Throughput Identification of Calcium Regulated Proteins Across Diverse Proteomes
TM Locke, R Fields, H Gizinski, GM Otto, DM Shechner, MD Berg, J Villen, ...
bioRxiv, 2024.01. 18.575273, 2024
12024
Targeting Noncoding RNA Domains to Genomic Loci with CRISPR-Display: Guidelines for Designing, Building, and Testing sgRNA–ncRNA Expression Constructs
DM Shechner
CRISPR Guide RNA Design: Methods and Protocols, 115-152, 2021
12021
Architecture of an RNA polymerase ribozyme illuminates the RNA World
DM Shechner
Trends in Genetics, 2024
2024
Programmable peroxidase-assisted signal amplification enables flexible detection of nucleic acid targets in cellular and histopathological specimens
S Attar, VE Browning, Y Liu, EK Nichols, AF Tsue, DM Shechner, ...
bioRxiv, 2023.01. 30.526264, 2023
2023
Efficient and highly amplified imaging of nucleic acid targets in cellular and histopathological samples with pSABER
S Attar, VE Browning, Y Liu, EK Nichols, AF Tsue, DM Shechner, ...
bioRxiv, 2023.01. 30.526264, 2023
2023
Oligonucleotide-directed proximity-interactome mapping (O-MAP): A unified method for discovering RNA-interactions and probing RNA-scaffolded compartments within intact cells
D Shechner, A Tsue, E Kania, R Fields, X Deng, SE Ong, C Disteche, ...
Journal of Biological Chemistry 299 (3), S678, 2023
2023
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