Toivo Maimets
Toivo Maimets
University of Tartu
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Challenges with advanced therapy medicinal products and how to meet them
Nature reviews Drug discovery 9 (3), 195-201, 2010
p53 interacts with p34cdc2 in mammalian cells: implications for cell cycle control and oncogenesis.
HW Stürzbecher, T Maimets, P Chumakov, R Brain, C Addison, V Simanis, ...
Oncogene 5 (6), 795-781, 1990
Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells
T Maimets, I Neganova, L Armstrong, M Lako
Oncogene 27 (40), 5277-5287, 2008
Characterization of a novel cytotoxic cell‐penetrating peptide derived from p14ARF protein
HJ Johansson, S El-Andaloussi, T Holm, M Mäe, J Jänes, T Maimets, ...
Molecular Therapy 16 (1), 115-123, 2008
Mouse p53 blocks SV40 DNA replication in vitro and downregulates T antigen DNA helicase activity.
HW Stürzbecher, R Brain, T Maimets, C Addison, K Rudge, JR Jenkins
Oncogene 3 (4), 405-413, 1988
ARF and ATM/ATR cooperate in p53-mediated apoptosis upon oncogenic stress
S Pauklin, A Kristjuhan, T Maimets, V Jaks
Biochemical and biophysical research communications 334 (2), 386-394, 2005
p53 protein is a suppressor of papillomavirus DNA amplificational replication
D Lepik, I Ilves, A Kristjuhan, T Maimets, M Ustav
Journal of virology 72 (8), 6822-6831, 1998
Pre-administration of PepFect6-microRNA-146a nanocomplexes inhibits inflammatory responses in keratinocytes and in a mouse model of irritant contact dermatitis
E Urgard, A Lorents, M Klaas, K Padari, J Viil, T Runnel, K Langel, ...
Journal of Controlled Release 235, 195-204, 2016
p53-dependent transcription can exhibit both on/off and graded response after genotoxic stress
A Joers, V Jaks, J Kase, T Maimets
Oncogene 23 (37), 6175-6185, 2004
SOX2 is regulated differently from NANOG and OCT4 in human embryonic stem cells during early differentiation initiated with sodium butyrate
A Kallas, M Pook, A Trei, T Maimets
Stem cells international 2014 (1), 298163, 2014
Nocodazole treatment decreases expression of pluripotency markers Nanog and Oct4 in human embryonic stem cells
A Kallas, M Pook, M Maimets, K Zimmermann, T Maimets
PLoS One 6 (4), e19114, 2011
Electroporation and carrier DNA cause p53 activation, cell cycle arrest, and apoptosis
D Lepik, V Jaks, L Kadaja, S Värv, T Maimets
Analytical biochemistry 318 (1), 52-59, 2003
A human tumour-derived mutant p53 protein induces a p34cdc2 reversible growth arrest in fission yeast.
P Wagner, V Simanis, T Maimets, E Keenan, C Addison, R Brain, ...
Oncogene 6 (9), 1539-1547, 1991
Overexpression of leukocyte marker CD43 causes activation of the tumor suppressor proteins p53 and ARF
L Kadaja, S Laos, T Maimets
Oncogene 23 (14), 2523-2530, 2004
miR‐10a‐5p is increased in atopic dermatitis and has capacity to inhibit keratinocyte proliferation
H Vaher, T Runnel, E Urgard, A Aab, G Carreras Badosa, J Maslovskaja, ...
Allergy 74 (11), 2146-2156, 2019
Tumour associated mutants of p53 can inhibit transcriptional activity of p53 without heterooligomerization
A Joers, A Kristjuhan, L Kadaja, T Maimets
Oncogene 17 (18), 2351-2358, 1998
Colon cancer cell differentiation by sodium butyrate modulates metabolic plasticity of Caco-2 cells via alteration of phosphotransfer network
L Klepinina, A Klepinin, L Truu, V Chekulayev, H Vija, K Kuus, I Teino, ...
PLoS One 16 (1), e0245348, 2021
Targeted gene silencing in human embryonic stem cells using cell-penetrating peptide PepFect 14
EH Ervin, M Pook, I Teino, V Kasuk, A Trei, M Pooga, T Maimets
Stem Cell Research & Therapy 10, 1-14, 2019
Interim evaluation of the seventh framework programme: report of the expert group
R Annerberg, I Begg, H Acherson, S Borrás, A Hallen, T Maimets, ...
European Commission, 2010
p53 protein accumulation in addition to the transactivation activity is required for p53-dependent cell cycle arrest after treatment of cells with camptothecin
V Jaks, A Jõers, A Kristjuhan, T Maimets
Oncogene 20 (10), 1212-1219, 2001
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