IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior P Chakrabarty, A Li, C Ceballos-Diaz, JA Eddy, CC Funk, B Moore, ... Neuron 85 (3), 519-533, 2015 | 378 | 2015 |
Massive gliosis induced by interleukin-6 suppresses Aβ deposition in vivo: evidence against inflammation as a driving force for amyloid deposition P Chakrabarty, K Jansen-West, A Beccard, C Ceballos-Diaz, Y Levites, ... The FASEB Journal 24 (2), 548, 2010 | 368 | 2010 |
IFN-γ promotes complement expression and attenuates amyloid plaque deposition in amyloid β precursor protein transgenic mice P Chakrabarty, C Ceballos-Diaz, A Beccard, C Janus, D Dickson, ... The Journal of Immunology 184 (9), 5333-5343, 2010 | 206 | 2010 |
Capsid serotype and timing of injection determines AAV transduction in the neonatal mice brain P Chakrabarty, A Rosario, P Cruz, Z Siemienski, C Ceballos-Diaz, ... PloS one 8 (6), e67680, 2013 | 201 | 2013 |
Viral transduction of the neonatal brain delivers controllable genetic mosaicism for visualising and manipulating neuronal circuits in vivo JY Kim, RT Ash, C Ceballos‐Diaz, Y Levites, TE Golde, SM Smirnakis, ... European Journal of Neuroscience 37 (8), 1203-1220, 2013 | 141 | 2013 |
Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo P Chakrabarty, A Herring, C Ceballos-Diaz, P Das, TE Golde Molecular neurodegeneration 6, 1-10, 2011 | 137 | 2011 |
Amyloidogenic α-synuclein seeds do not invariably induce rapid, widespread pathology in mice AN Sacino, M Brooks, MA Thomas, AB McKinney, NH McGarvey, ... Acta neuropathologica 127, 645-665, 2014 | 129 | 2014 |
Identification of CKAP4/p63 as a major substrate of the palmitoyl acyltransferase DHHC2, a putative tumor suppressor, using a novel proteomics method J Zhang, SL Planey, C Ceballos, SM Stevens, SK Keay, DA Zacharias Molecular & Cellular Proteomics 7 (7), 1378-1388, 2008 | 125 | 2008 |
Microglia-specific targeting by novel capsid-modified AAV6 vectors AM Rosario, PE Cruz, C Ceballos-Diaz, MR Strickland, Z Siemienski, ... Molecular Therapy Methods & Clinical Development 3, 2016 | 123 | 2016 |
Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition P Chakrabarty, L Tianbai, A Herring, C Ceballos-Diaz, P Das, TE Golde Molecular neurodegeneration 7, 1-12, 2012 | 119 | 2012 |
Convection-enhanced delivery and systemic mannitol increase gene product distribution of AAV vectors 5, 8, and 9 and increase gene product in the adult mouse brain N Carty, D Lee, C Dickey, C Ceballos-Diaz, K Jansen-West, TE Golde, ... Journal of neuroscience methods 194 (1), 144-153, 2010 | 89 | 2010 |
5-Lipoxygenase gene transfer worsens memory, amyloid and tau brain pathologies in a mouse model of AD J Chu, PF Giannopoulos, C Ceballos-Diaz, TE Golde, D Pratico Annals of neurology 72 (3), 442, 2012 | 88 | 2012 |
Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis C Verbeeck, Q Deng, M DeJesus-Hernandez, G Taylor, C Ceballos-Diaz, ... Molecular neurodegeneration 7, 1-13, 2012 | 86 | 2012 |
Interferon-γ induces progressive nigrostriatal degeneration and basal ganglia calcification P Chakrabarty, C Ceballos-Diaz, WL Lin, A Beccard, K Jansen-West, ... Nature neuroscience 14 (6), 694-696, 2011 | 83 | 2011 |
Conformational templating of α-synuclein aggregates in neuronal-glial cultures AN Sacino, MA Thomas, C Ceballos-Diaz, PE Cruz, AM Rosario, J Lewis, ... Molecular neurodegeneration 8, 1-16, 2013 | 73 | 2013 |
Short Aβ peptides attenuate Aβ42 toxicity in vivo BD Moore, J Martin, L de Mena, J Sanchez, PE Cruz, C Ceballos-Diaz, ... Journal of Experimental Medicine 215 (1), 283-301, 2018 | 72 | 2018 |
Adeno-associated virus-mediated brain delivery of 5-lipoxygenase modulates the AD-like phenotype of APP mice J Chu, PF Giannopoulos, C Ceballos-Diaz, TE Golde, D Pratico Molecular Neurodegeneration 7, 1-10, 2012 | 67 | 2012 |
Widespread and efficient transduction of spinal cord and brain following neonatal AAV injection and potential disease modifying effect in ALS mice JI Ayers, S Fromholt, O Sinyavskaya, Z Siemienski, AM Rosario, A Li, ... Molecular Therapy 23 (1), 53-62, 2015 | 62 | 2015 |
Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice C Ceballos-Diaz, AM Rosario, HJ Park, P Chakrabarty, A Sacino, PE Cruz, ... Molecular neurodegeneration 10, 1-13, 2015 | 60 | 2015 |
TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer’s disease P Chakrabarty, A Li, TB Ladd, MR Strickland, EJ Koller, JD Burgess, ... Journal of Experimental Medicine 215 (9), 2247-2264, 2018 | 56 | 2018 |