| Double genetic disruption of lactate dehydrogenases A and B is required to ablate the “Warburg effect” restricting tumor growth to oxidative metabolism M Ždralević, A Brand, L Di Ianni, K Dettmer, J Reinders, K Singer, K Peter, ... Journal of Biological Chemistry 293 (41), 15947-15961, 2018 | 187 | 2018 |
| The HIF-1–inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth F Pez, F Dayan, J Durivault, B Kaniewski, G Aimond, GS Le Provost, ... Cancer research 71 (5), 1647-1657, 2011 | 179 | 2011 |
| Genetic ablation of the cystine transporter xCT in PDAC cells inhibits mTORC1, growth, survival, and tumor formation via nutrient and oxidative stresses B Daher, SK Parks, J Durivault, Y Cormerais, H Baidarjad, E Tambutte, ... Cancer research 79 (15), 3877-3890, 2019 | 167 | 2019 |
| Genetic disruption of the multifunctional CD98/LAT1 complex demonstrates the key role of essential amino acid transport in the control of mTORC1 and tumor growth Y Cormerais, S Giuliano, R LeFloch, B Front, J Durivault, E Tambutté, ... Cancer research 76 (15), 4481-4492, 2016 | 158 | 2016 |
| The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5) Y Cormerais, PA Massard, M Vucetic, S Giuliano, E Tambutté, J Durivault, ... Journal of Biological Chemistry 293 (8), 2877-2887, 2018 | 155 | 2018 |
| Disrupting glucose-6-phosphate isomerase fully suppresses the “Warburg effect” and activates OXPHOS with minimal impact on tumor growth except in hypoxia MC de Padua, G Delodi, M Vučetić, J Durivault, V Vial, P Bayer, ... Oncotarget 8 (50), 87623, 2017 | 82 | 2017 |
| Acceleration of clear cell renal cell carcinoma growth in mice following bevacizumab/Avastin treatment: the role of CXCL cytokines R Grepin, M Guyot, M Jacquin, J Durivault, E Chamorey, A Sudaka, ... Oncogene 31 (13), 1683-1694, 2012 | 77 | 2012 |
| Fas palmitoylation by the palmitoyl acyltransferase DHHC7 regulates Fas stability A Rossin, J Durivault, T Chakhtoura-Feghali, N Lounnas, ... Cell Death & Differentiation 22 (4), 643-653, 2015 | 73 | 2015 |
| ‘Warburg effect’controls tumor growth, bacterial, viral infections and immunity–Genetic deconstruction and therapeutic perspectives J Pouysségur, I Marchiq, SK Parks, J Durivault, M Ždralević, M Vucetic Seminars in cancer biology 86, 334-346, 2022 | 55 | 2022 |
| Genetic disruption of the pHi-regulating proteins Na+/H+ exchanger 1 (SLC9A1) and carbonic anhydrase 9 severely reduces growth of colon cancer cells SK Parks, Y Cormerais, J Durivault, J Pouyssegur Oncotarget 8 (6), 10225, 2017 | 55 | 2017 |
| Bevacizumab/docetaxel association is more efficient than docetaxel alone in reducing breast and prostate cancer cell growth: a new paradigm for understanding the therapeutic … C Ortholan, J Durivault, JM Hannoun-Levi, M Guyot, C Bourcier, ... European journal of cancer 46 (16), 3022-3036, 2010 | 41 | 2010 |
| The asparaginyl hydroxylase factor-inhibiting HIF is essential for tumor growth through suppression of the p53–p21 axis J Pelletier, F Dayan, J Durivault, K Ilc, E Pecou, J Pouyssegur, NM Mazure Oncogene 31 (24), 2989-3001, 2012 | 38 | 2012 |
| Targeting the pro-angiogenic forms of VEGF or inhibiting their expression as anti-cancer strategies M Guyot, C Hilmi, D Ambrosetti, M Merlano, CL Nigro, J Durivault, ... Oncotarget 8 (6), 9174, 2017 | 30 | 2017 |
| VEGFC acts as a double-edged sword in renal cell carcinoma aggressiveness PD Ndiaye, M Dufies, S Giuliano, L Douguet, R Grépin, J Durivault, ... Theranostics 9 (3), 661, 2019 | 29 | 2019 |
| An evolution-guided analysis reveals a multi-signaling regulation of Fas by tyrosine phosphorylation and its implication in human cancers K Chakrabandhu, S Huault, J Durivault, K Lang, L Ta Ngoc, A Bole, ... PLoS biology 14 (3), e1002401, 2016 | 25 | 2016 |
| The combination of bevacizumab/Avastin and erlotinib/Tarceva is relevant for the treatment of metastatic renal cell carcinoma: the role of a synonymous mutation of the EGFR … R Grépin, M Guyot, A Dumond, J Durivault, D Ambrosetti, JF Roussel, ... Theranostics 10 (3), 1107, 2020 | 19 | 2020 |
| A Cystine-Cysteine Intercellular Shuttle Prevents Ferroptosis in xCTKO Pancreatic Ductal Adenocarcinoma Cells W Meira, B Daher, SK Parks, Y Cormerais, J Durivault, E Tambutte, ... Cancers 13 (6), 1434, 2021 | 17 | 2021 |
| AKT1 restricts the invasive capacity of head and neck carcinoma cells harboring a constitutively active PI3 kinase activity S Brolih, SK Parks, V Vial, J Durivault, L Mostosi, J Pouysségur, G Pagès, ... Bmc Cancer 18, 1-10, 2018 | 15 | 2018 |
| Neuropilin 1 and Neuropilin 2 gene invalidation or pharmacological inhibition reveals their relevance for the treatment of metastatic renal cell carcinoma A Dumond, E Brachet, J Durivault, V Vial, AK Puszko, Y Lepelletier, ... Journal of experimental & clinical cancer research 40, 1-18, 2021 | 14 | 2021 |
| Pancreatic ductal adenocarcinoma: the dawn of the era of nuclear medicine? C Montemagno, S Cassim, N De Leiris, J Durivault, M Faraggi, G Pagès International Journal of Molecular Sciences 22 (12), 6413, 2021 | 13 | 2021 |
