The septic heart: current understanding of molecular mechanisms and clinical implications L Martin, M Derwall, S Al Zoubi, E Zechendorf, DA Reuter, ... Chest 155 (2), 427-437, 2019 | 252 | 2019 |
The endothelial glycocalyx: new diagnostic and therapeutic approaches in sepsis L Martin, P Koczera, E Zechendorf, T Schuerholz BioMed research international 2016, 2016 | 150 | 2016 |
The ribonuclease a superfamily in humans: canonical RNases as the buttress of innate immunity P Koczera, L Martin, G Marx, T Schuerholz International journal of molecular sciences 17 (8), 1278, 2016 | 132 | 2016 |
Antimicrobial peptides in human sepsis L Martin, A Van Meegern, S Doemming, T Schuerholz Frontiers in immunology 6, 404, 2015 | 132 | 2015 |
Telemedicine in Germany during the COVID-19 pandemic: multi-professional national survey A Peine, P Paffenholz, L Martin, S Dohmen, G Marx, SH Loosen Journal of medical Internet research 22 (8), e19745, 2020 | 119 | 2020 |
The acute respiratory distress syndrome: pathophysiology, current clinical practice, and emerging therapies M Derwall, L Martin, R Rossaint Expert Review of Respiratory Medicine 12 (12), 1021-1029, 2018 | 74 | 2018 |
Perception of the 2020 SARS-CoV-2 pandemic among medical professionals in Germany: results from a nationwide online survey P Paffenholz, A Peine, M Hellmich, SV Paffenholz, L Martin, M Luedde, ... Emerging microbes & infections 9 (1), 1590-1599, 2020 | 67 | 2020 |
Development and validation of a reinforcement learning algorithm to dynamically optimize mechanical ventilation in critical care A Peine, A Hallawa, J Bickenbach, G Dartmann, LB Fazlic, A Schmeink, ... NPJ digital medicine 4 (1), 32, 2021 | 65 | 2021 |
The anti-inflammatory effect of the synthetic antimicrobial peptide 19-2.5 in a murine sepsis model: a prospective randomized study T Schuerholz, S Doemming, M Hornef, L Martin, TP Simon, L Heinbockel, ... Critical Care 17, 1-9, 2013 | 58 | 2013 |
The synthetic antimicrobial peptide 19-2.5 interacts with heparanase and heparan sulfate in murine and human sepsis L Martin, R De Santis, P Koczera, N Simons, H Haase, L Heinbockel, ... PloS one 10 (11), e0143583, 2015 | 56 | 2015 |
Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes GSD Purvis, F Chiazza, J Chen, R Azevedo-Loiola, L Martin, ... Diabetologia 61, 482-495, 2018 | 52 | 2018 |
Peptide 19-2.5 inhibits heparan sulfate-triggered inflammation in murine cardiomyocytes stimulated with human sepsis serum L Martin, S Schmitz, R De Santis, S Doemming, H Haase, J Hoeger, ... PloS one 10 (5), e0127584, 2015 | 50 | 2015 |
Soluble heparan sulfate in serum of septic shock patients induces mitochondrial dysfunction in murine cardiomyocytes L Martin, C Peters, S Schmitz, J Moellmann, A Martincuks, N Heussen, ... Shock 44 (6), 569-577, 2015 | 49 | 2015 |
Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis E Zechendorf, CE O’Riordan, L Stiehler, N Wischmeyer, F Chiazza, ... JCI insight 5 (8), 2020 | 41 | 2020 |
Heart in sepsis: molecular mechanisms, diagnosis and therapy of septic cardiomyopathy L Martin, M Derwall, C Thiemermann, T Schürholz Der Anaesthesist 66, 479-490, 2017 | 39 | 2017 |
The synthetic antimicrobial peptide 19-2.5 attenuates septic cardiomyopathy and prevents down-regulation of SERCA2 in polymicrobial sepsis L Martin, K Horst, F Chiazza, S Oggero, M Collino, K Brandenburg, ... Scientific reports 6 (1), 37277, 2016 | 38 | 2016 |
Linagliptin attenuates the cardiac dysfunction associated with experimental sepsis in mice with pre-existing type 2 diabetes by inhibiting NF-κB S Al Zoubi, J Chen, C Murphy, L Martin, F Chiazza, D Collotta, ... Frontiers in immunology 9, 423123, 2018 | 36 | 2018 |
Bruton's tyrosine kinase inhibition attenuates the cardiac dysfunction caused by cecal ligation and puncture in mice CE O'Riordan, GSD Purvis, D Collotta, F Chiazza, B Wissuwa, S Al Zoubi, ... Frontiers in Immunology 10, 465227, 2019 | 35 | 2019 |
Plasma adrenomedullin in critically ill patients with sepsis after major surgery: a pilot study TP Simon, L Martin, S Doemming, A Humbs, C Bruells, R Kopp, ... Journal of critical care 38, 68-72, 2017 | 30 | 2017 |
RvE1 attenuates polymicrobial sepsis-induced cardiac dysfunction and enhances bacterial clearance J Chen, GSD Purvis, D Collotta, S Al Zoubi, MA Sugimoto, A Cacace, ... Frontiers in immunology 11, 2080, 2020 | 27 | 2020 |