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Ned Van Eps
Ned Van Eps
Tuntematon yhteys
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Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
Y Kang, XE Zhou, X Gao, Y He, W Liu, A Ishchenko, A Barty, TA White, ...
Nature 523 (7562), 561-567, 2015
8292015
Identification of phosphorylation codes for arrestin recruitment by G protein-coupled receptors
XE Zhou, Y He, PW de Waal, X Gao, Y Kang, N Van Eps, Y Yin, K Pal, ...
Cell 170 (3), 457-469. e13, 2017
3922017
Activation of the A2A adenosine G-protein-coupled receptor by conformational selection
L Ye, N Van Eps, M Zimmer, OP Ernst, R Scott Prosser
Nature 533 (7602), 265-268, 2016
3382016
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein
Y Kang, O Kuybeda, PW de Waal, S Mukherjee, N Van Eps, P Dutka, ...
Nature 558 (7711), 553-558, 2018
2512018
Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins
WM Oldham, N Van Eps, AM Preininger, WL Hubbell, HE Hamm
Nature structural & molecular biology 13 (9), 772-777, 2006
2322006
Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit
N Van Eps, AM Preininger, N Alexander, AI Kaya, S Meier, J Meiler, ...
Proceedings of the National Academy of Sciences 108 (23), 9420-9424, 2011
1922011
Site-directed spin labeling measurements of nanometer distances in nucleic acids using a sequence-independent nitroxide probe
Q Cai, AK Kusnetzow, WL Hubbell, IS Haworth, GPC Gacho, N Van Eps, ...
Nucleic acids research 34 (17), 4722-4730, 2006
1562006
Conformation of receptor-bound visual arrestin
M Kim, SA Vishnivetskiy, N Van Eps, NS Alexander, WM Cleghorn, ...
Proceedings of the National Academy of Sciences 109 (45), 18407-18412, 2012
1232012
Structure and function of the visual arrestin oligomer
SM Hanson, N Van Eps, DJ Francis, C Altenbach, SA Vishnivetskiy, ...
The EMBO journal 26 (6), 1726-1736, 2007
1232007
Structure of the glucagon receptor in complex with a glucagon analogue
H Zhang, A Qiao, L Yang, N Van Eps, KS Frederiksen, D Yang, A Dai, ...
Nature 553 (7686), 106-110, 2018
1142018
Conformational equilibria of light-activated rhodopsin in nanodiscs
N Van Eps, LN Caro, T Morizumi, AK Kusnetzow, M Szczepek, ...
Proceedings of the National Academy of Sciences 114 (16), E3268-E3275, 2017
1032017
Structural and dynamical changes in an α-subunit of a heterotrimeric G protein along the activation pathway
N Van Eps, WM Oldham, HE Hamm, WL Hubbell
Proceedings of the National Academy of Sciences 103 (44), 16194-16199, 2006
992006
Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins
WM Oldham, N Van Eps, AM Preininger, WL Hubbell, HE Hamm
Proceedings of the National Academy of Sciences 104 (19), 7927-7932, 2007
872007
Gi-and Gs-coupled GPCRs show different modes of G-protein binding
N Van Eps, C Altenbach, LN Caro, NR Latorraca, SA Hollingsworth, ...
Proceedings of the National Academy of Sciences 115 (10), 2383-2388, 2018
852018
A model for the solution structure of the rod arrestin tetramer
SM Hanson, ES Dawson, DJ Francis, N Van Eps, CS Klug, WL Hubbell, ...
Structure 16 (6), 924-934, 2008
812008
Cryo-EM structure of the native rhodopsin dimer in nanodiscs
DY Zhao, M Pöge, T Morizumi, S Gulati, N Van Eps, J Zhang, P Miszta, ...
Journal of Biological Chemistry 294 (39), 14215-14230, 2019
762019
The role of arrestin α-helix I in receptor binding
SA Vishnivetskiy, D Francis, N Van Eps, M Kim, SM Hanson, CS Klug, ...
Journal of molecular biology 395 (1), 42-54, 2010
722010
X-ray Crystallographic Structure and Oligomerization of Gloeobacter Rhodopsin
T Morizumi, WL Ou, N Van Eps, K Inoue, H Kandori, LS Brown, OP Ernst
Scientific Reports 9 (1), 11283, 2019
672019
The Myristoylated Amino Terminus of Gαi1 Plays a Critical Role in the Structure and Function of Gαi1 Subunits in Solution
AM Preininger, N Van Eps, NJ Yu, M Medkova, WL Hubbell, HE Hamm
Biochemistry 42 (26), 7931-7941, 2003
582003
The guanine nucleotide exchange factor Ric-8A induces domain separation and Ras domain plasticity in Gαi1
N Van Eps, CJ Thomas, WL Hubbell, SR Sprang
Proceedings of the National Academy of Sciences 112 (5), 1404-1409, 2015
372015
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Artikkelit 1–20