TP53 mutations in myelodysplastic syndrome are strongly correlated with aberrations of chromosome 5, and correlate with adverse prognosis AG Kulasekararaj, AE Smith, SA Mian, AM Mohamedali, P Krishnamurthy, ... British journal of haematology 160 (5), 660-672, 2013 | 317 | 2013 |
Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite … AE Smith, AM Mohamedali, A Kulasekararaj, ZY Lim, J Gäken, NC Lea, ... Blood, The Journal of the American Society of Hematology 116 (19), 3923-3932, 2010 | 299 | 2010 |
Somatic mutations identify a subgroup of aplastic anemia patients who progress to myelodysplastic syndrome AG Kulasekararaj, J Jiang, AE Smith, AM Mohamedali, S Mian, S Gandhi, ... Blood, The Journal of the American Society of Hematology 124 (17), 2698-2704, 2014 | 267 | 2014 |
Functional characterization of CD4+ T cells in aplastic anemia S Kordasti, J Marsh, S Al-Khan, J Jiang, A Smith, A Mohamedali, ... Blood, The Journal of the American Society of Hematology 119 (9), 2033-2043, 2012 | 213 | 2012 |
Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment S Kordasti, B Costantini, T Seidl, P Perez Abellan, M Martinez Llordella, ... Blood, The Journal of the American Society of Hematology 128 (9), 1193-1205, 2016 | 138 | 2016 |
Modeling the human bone marrow niche in mice: From host bone marrow engraftment to bioengineering approaches A Abarrategi, SA Mian, D Passaro, K Rouault-Pierre, W Grey, D Bonnet Journal of Experimental Medicine 215 (3), 729-743, 2018 | 116 | 2018 |
Versatile humanized niche model enables study of normal and malignant human hematopoiesis A Abarrategi, K Foster, A Hamilton, SA Mian, D Passaro, J Gribben, ... The Journal of clinical investigation 127 (2), 543-548, 2017 | 97 | 2017 |
Spliceosome mutations exhibit specific associations with epigenetic modifiers and proto-oncogenes mutated in myelodysplastic syndrome SA Mian, AE Smith, AG Kulasekararaj, A Kizilors, AM Mohamedali, ... Haematologica 98 (7), 1058, 2013 | 95 | 2013 |
Novel TET2 Mutations Associated With UPD4q24 in Myelodysplastic Syndrome AM Mohamedali, AE Smith, J Gaken, NC Lea, SA Mian, NB Westwood, ... Journal of clinical oncology 27 (24), 4002-4006, 2009 | 94 | 2009 |
SF3B1 mutant MDS-initiating cells may arise from the haematopoietic stem cell compartment SA Mian, K Rouault-Pierre, AE Smith, T Seidl, I Pizzitola, A Kizilors, ... Nature communications 6 (1), 10004, 2015 | 90 | 2015 |
Effect of low-level BCR-ABL1 kinase domain mutations identified by next-generation sequencing in patients with chronic myeloid leukaemia: a population-based study A Kizilors, E Crisà, N Lea, R Passera, S Mian, J Anwar, S Best, FE Nicolini, ... The Lancet Haematology 6 (5), e276-e284, 2019 | 54 | 2019 |
The combination of CHK1 inhibitor with G-CSF overrides cytarabine resistance in human acute myeloid leukemia A Di Tullio, K Rouault-Pierre, A Abarrategi, S Mian, W Grey, J Gribben, ... Nature communications 8 (1), 1679, 2017 | 53 | 2017 |
High concordance of genomic and cytogenetic aberrations between peripheral blood and bone marrow in myelodysplastic syndrome (MDS) AM Mohamedali, J Gäken, M Ahmed, F Malik, AE Smith, S Best, S Mian, ... Leukemia 29 (9), 1928-1938, 2015 | 46 | 2015 |
Utility of peripheral blood for cytogenetic and mutation analysis in myelodysplastic syndrome AM Mohamedali, H Alkhatabi, A Kulasekararaj, S Shinde, S Mian, F Malik, ... Blood, The Journal of the American Society of Hematology 122 (4), 567-570, 2013 | 40 | 2013 |
Preclinical modeling of myelodysplastic syndromes K Rouault-Pierre, SA Mian, M Goulard, A Abarrategi, A Di Tulio, AE Smith, ... Leukemia 31 (12), 2702-2708, 2017 | 39 | 2017 |
Single cell analyses identify a highly regenerative and homogenous human CD34+ hematopoietic stem cell population F Anjos-Afonso, F Buettner, SA Mian, H Rhys, J Perez-Lloret, ... Nature communications 13 (1), 2048, 2022 | 31 | 2022 |
Advances in human immune system mouse models for studying human hematopoiesis and cancer immunotherapy SA Mian, F Anjos-Afonso, D Bonnet Frontiers in immunology 11, 619236, 2021 | 28 | 2021 |
Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells SA Mian, A Abarrategi, KL Kong, K Rouault-Pierre, H Wood, ... Blood cancer discovery 2 (2), 135-145, 2021 | 26 | 2021 |
CSNK1A1 mutations and isolated del (5q) abnormality in myelodysplastic syndrome: a retrospective mutational analysis AE Smith, AG Kulasekararaj, J Jiang, S Mian, A Mohamedali, J Gaken, ... The Lancet Haematology 2 (5), e212-e221, 2015 | 23 | 2015 |
Polycomb complex group gene mutations and their prognostic relevance in 5-azacitidine treated myelodysplastic syndrome patients AG Kulasekararaj, AM Mohamedali, AE Smith, NC Lea, A Kizilors, ... Blood 116 (21), 125, 2010 | 21 | 2010 |