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Marko Rosenholm
Marko Rosenholm
Verified email at sund.ku.dk
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Cortical excitability and activation of TrkB signaling during rebound slow oscillations are critical for rapid antidepressant responses
S Kohtala, W Theilmann, M Rosenholm, L Penna, G Karabulut, S Uusitalo, ...
Molecular Neurobiology 56, 4163-4174, 2019
432019
Time is of the essence: coupling sleep-wake and circadian neurobiology to the antidepressant effects of ketamine
S Kohtala, O Alitalo, M Rosenholm, S Rozov, T Rantamäki
Pharmacology & Therapeutics 221, 107741, 2021
292021
Ketamine-induced regulation of TrkB-GSK3β signaling is accompanied by slow EEG oscillations and sedation but is independent of hydroxynorketamine metabolites
S Kohtala, W Theilmann, M Rosenholm, HK Müller, P Kiuru, G Wegener, ...
Neuropharmacology 157, 107684, 2019
242019
ADHD-like behaviors caused by inactivation of a transcription factor controlling the balance of inhibitory and excitatory neuron development in the mouse anterior brainstem
F Morello, V Voikar, P Parkkinen, A Panhelainen, M Rosenholm, ...
Translational psychiatry 10 (1), 357, 2020
192020
Repeated brief isoflurane anesthesia during early postnatal development produces negligible changes on adult behavior in male mice
M Rosenholm, E Paro, H Antila, V Voikar, T Rantamäki
PloS one 12 (4), e0175258, 2017
182017
Systemic hypertonic saline enhances glymphatic spinal cord delivery of lumbar intrathecal morphine
KJ Blomqvist, MOB Skogster, MJ Kurkela, MP Rosenholm, FHG Ahlström, ...
Journal of Controlled Release 344, 214-224, 2022
112022
A SPECT-based method for dynamic imaging of the glymphatic system in rats
B Sigurdsson, NL Hauglund, TO Lilius, FLH Mogensen, KN Mortensen, ...
Journal of Cerebral Blood Flow & Metabolism 43 (7), 1153-1165, 2023
82023
Glymphatic-assisted perivascular brain delivery of intrathecal small gold nanoparticles
TO Lilius, KN Mortensen, C Deville, TJ Lohela, FF Stæger, B Sigurdsson, ...
Journal of Controlled Release 355, 135-148, 2023
62023
Lack of antidepressant effects of burst-suppressing isoflurane anesthesia in adult male Wistar outbred rats subjected to chronic mild stress
W Theilmann, M Rosenholm, P Hampel, W Loescher, T Rantamäki
PLoS One 15 (6), e0235046, 2020
62020
Ketamine reduces electrophysiological network activity in cortical neuron cultures already at sub-micromolar concentrations–Impact on TrkB-ERK1/2 signaling
A Ahtiainen, I Annala, M Rosenholm, S Kohtala, J Hyttinen, ...
Neuropharmacology 229, 109481, 2023
32023
SPECT/CT imaging reveals CNS-wide modulation of glymphatic cerebrospinal fluid flow by systemic hypertonic saline
TO Lilius, M Rosenholm, L Klinger, KN Mortensen, B Sigurdsson, ...
Iscience 25 (10), 2022
32022
Linking Hypothermia and Altered Metabolism with TrkB Activation
O Alitalo, G González-Hernández, M Rosenholm, P Kohtala, N Matsui, ...
ACS chemical neuroscience 14 (17), 3212-3225, 2023
12023
Perivascular Cerebrospinal Fluid Flow is the Primary Source of Interstitial Fluid in the Anesthetized Rat Brain
K Mortensen, T Lilius, M Rosenholm, B Sigurðsson, DH Kelley, ...
Available at SSRN 4308439, 2022
12022
Physiological basis underlying antidepressant-induced activation of TrkB receptors
O Alitalo, S Kohtala, M Rosenholm, P Kohtala, R Saarreharju, N Matsui, ...
Biorxiv, 2021.08. 30.458151, 2021
12021
Anestesia-aineet säätelevät glymfaattista virtausta, likvortilojen kokoa ja likvorin ulosvirtausta keskushermostosta veren hiilidioksiditasoa voimakkaammin
NDÅ Persson, TJ Lohela, KN Mortensen, M Rosenholm, Q Li, ...
Finnanest. 56 (5), 305-305, 2023
2023
Glymfaattinen järjestelmä saattaa intratekaalisen lääkkeen selkäytimeen
KJ Blomqvist, MOB Skogster, MJ Kurkela, MP Rosenholm, FHG Ahlström, ...
Duodecim 138 (10), 949, 2022
2022
Tianeptine induces expression of dual specificity phosphatases and evokes rebound emergence of cortical slow wave electrophysiological activity
SV Rozov, M Rosenholm, S Hintikka, T Rantamäki
Neuroscience Letters 764, 136200, 2021
2021
Studies on the developmental and antidepressant-like effects of anesthetics
M Rosenholm
Helsingin yliopisto, 2020
2020
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