| Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes E Viganò, CE Diamond, R Spreafico, A Balachander, RM Sobota, ... Nature communications 6 (1), 8761, 2015 | 361 | 2015 |
| SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130 U Lehmann, J Schmitz, M Weissenbach, RM Sobota, M Hortner, ... Journal of Biological Chemistry 278 (1), 661-671, 2003 | 330 | 2003 |
| Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host M Ahn, DE Anderson, Q Zhang, CW Tan, BL Lim, K Luko, M Wen, ... Nature microbiology 4 (5), 789-799, 2019 | 294 | 2019 |
| Parthenolide inhibits activation of signal transducers and activators of transcription (STATs) induced by cytokines of the IL-6 family R Sobota, M Szwed, A Kasza, M Bugno, T Kordula Biochemical and biophysical research communications 267 (1), 329-333, 2000 | 197 | 2000 |
| Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding FL Zhong, K Robinson, DET Teo, KY Tan, C Lim, CR Harapas, CH Yu, ... Journal of Biological Chemistry 293 (49), 18864-18878, 2018 | 191 | 2018 |
| Thermal proximity coaggregation for system-wide profiling of protein complex dynamics in cells CSH Tan, KD Go, X Bisteau, L Dai, CH Yong, N Prabhu, MB Ozturk, ... Science 359 (6380), 1170-1177, 2018 | 188 | 2018 |
| Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay JM Dziekan, H Yu, D Chen, L Dai, G Wirjanata, A Larsson, N Prabhu, ... Science translational medicine 11 (473), eaau3174, 2019 | 178 | 2019 |
| Transplantation of endothelial progenitor cells improves neovascularization and left ventricular function after myocardial infarction in a rat model A Schuh, EA Liehn, A Sasse, M Hristov, R Sobota, M Kelm, MW Merx, ... Basic research in cardiology 103, 69-77, 2008 | 165 | 2008 |
| Modulation of protein-interaction states through the cell cycle L Dai, T Zhao, X Bisteau, W Sun, N Prabhu, YT Lim, RM Sobota, P Kaldis, ... Cell 173 (6), 1481-1494. e13, 2018 | 134 | 2018 |
| Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells. Gimpel P, Lee YL, Sobota RM, Calvi A, Koullourou V, Patel R, Mamchaoui K ... Current Biology, pii: S0960-9822(17)31069-2, 2017 | 129* | 2017 |
| A subset of Kupffer cells regulates metabolism through the expression of CD36 C Blériot, E Barreby, G Dunsmore, R Ballaire, S Chakarov, X Ficht, ... Immunity 54 (9), 2101-2116. e6, 2021 | 115 | 2021 |
| The role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS3 for desensitization of interleukin-6 signalling P Fischer, U Lehmann, RM Sobota, J Schmitz, C Niemand, S Linnemann, ... Biochemical Journal 378 (2), 449-460, 2004 | 110 | 2004 |
| SH3TC2, a protein mutant in Charcot–Marie–Tooth neuropathy, links peripheral nerve myelination to endosomal recycling C Stendel, A Roos, H Kleine, E Arnaud, M Özçelik, PNM Sidiropoulos, ... Brain 133 (8), 2462-2474, 2010 | 97 | 2010 |
| Mitochondrial peptide BRAWNIN is essential for vertebrate respiratory complex III assembly S Zhang, B Reljić, C Liang, B Kerouanton, JC Francisco, JH Peh, C Mary, ... Nature communications 11 (1), 1312, 2020 | 96 | 2020 |
| Cellular thermal shift assay for the identification of drug–target interactions in the Plasmodium falciparum proteome JM Dziekan, G Wirjanata, L Dai, KD Go, H Yu, YT Lim, L Chen, LC Wang, ... Nature protocols 15 (6), 1881-1921, 2020 | 80 | 2020 |
| Signal transduction of IL-6, leukemia-inhibitory factor, and oncostatin M: structural receptor requirements for signal attenuation D Anhuf, M Weissenbach, J Schmitz, R Sobota, HM Hermanns, S Radtke, ... The Journal of Immunology 165 (5), 2535-2543, 2000 | 77 | 2000 |
| Unbiased profiling of isogenic Huntington disease hPSC-derived CNS and peripheral cells reveals strong cell-type specificity of CAG length effects J Ooi, SR Langley, X Xu, KH Utami, B Sim, Y Huang, NP Harmston, ... Cell Reports 26 (9), 2494-2508. e7, 2019 | 72 | 2019 |
| Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality M Kitagawa, PJ Liao, KH Lee, J Wong, SC Shang, N Minami, ... Nature communications 8 (1), 2200, 2017 | 70 | 2017 |
| ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome KS Robinson, GA Toh, P Rozario, R Chua, S Bauernfried, Z Sun, ... Science 377 (6603), 328-335, 2022 | 67 | 2022 |
| Mechanisms of SOCS3 phosphorylation upon interleukin-6 stimulation: contributions of Src-and receptor-tyrosine kinases U Sommer, C Schmid, RM Sobota, U Lehmann, NJ Stevenson, ... Journal of Biological Chemistry 280 (36), 31478-31488, 2005 | 63 | 2005 |
