Functionalized 3-amino-imidazo [1, 2-a] pyridines: a novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors LR Odell, MT Nilsson, J Gising, O Lagerlund, D Muthas, A Nordqvist, ... Bioorganic & Medicinal Chemistry Letters 19 (16), 4790-4793, 2009 | 129 | 2009 |
Virtual screening and bioassay study of novel inhibitors for dengue virus mRNA cap (nucleoside-2′ O)-methyltransferase VB Luzhkov, B Selisko, A Nordqvist, F Peyrane, E Decroly, K Alvarez, ... Bioorganic & medicinal chemistry 15 (24), 7795-7802, 2007 | 95 | 2007 |
Synthesis of Functionalized Cinnamaldehyde Derivatives by an Oxidative Heck Reaction and Their Use as Starting Materials for Preparation of Mycobacterium tuberculosis 1 … A Nordqvist, C Björkelid, M Andaloussi, AM Jansson, SL Mowbray, ... The Journal of Organic Chemistry 76 (21), 8986-8998, 2011 | 77 | 2011 |
Links between bacterial production, amino-acid utilization and community composition in productive lakes S Bertilsson, A Eiler, A Nordqvist, NOG Jørgensen The ISME journal 1 (6), 532-544, 2007 | 64 | 2007 |
A general model for prediction of Caco‐2 cell permeability A Nordqvist, J Nilsson, T Lindmark, A Eriksson, P Garberg, M Kihlén QSAR & Combinatorial Science 23 (5), 303-310, 2004 | 49 | 2004 |
Synthesis, biological evaluation and X-ray crystallographic studies of imidazo [1, 2-a] pyridine-based Mycobacterium tuberculosis glutamine synthetase inhibitors A Nordqvist, MT Nilsson, O Lagerlund, D Muthas, J Gising, S Yahiaoui, ... MedChemComm 3 (5), 620-626, 2012 | 48 | 2012 |
Evaluation of the amino acid binding site of Mycobacterium tuberculosis glutamine synthetase for drug discovery A Nordqvist, MT Nilsson, S Röttger, LR Odell, WW Krajewski, ... Bioorganic & medicinal chemistry 16 (10), 5501-5513, 2008 | 44 | 2008 |
GPR103 Antagonists Demonstrating Anorexigenic Activity in Vivo: Design and Development of Pyrrolo[2,3-c]pyridines That Mimic the C-Terminal Arg-Phe Motif of … J Georgsson, F Bergström, A Nordqvist, MJ Watson, CD Blundell, ... Journal of Medicinal Chemistry 57 (14), 5935-5948, 2014 | 27* | 2014 |
Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition AJ Kennedy, L Sundström, S Geschwindner, EKY Poon, Y Jiang, R Chen, ... Communications biology 3 (1), 782, 2020 | 26 | 2020 |
Quantitative structure–activity relationships of pine weevil antifeedants, a multivariate approach K Sunnerheim, A Nordqvist, G Nordlander, AK Borg-Karlson, CR Unelius, ... Journal of agricultural and food chemistry 55 (23), 9365-9372, 2007 | 26 | 2007 |
Discovery of retinoic acid receptor agonists as proliferators of cardiac progenitor cells through a phenotypic screening approach L Drowley, J McPheat, A Nordqvist, S Peel, U Karlsson, S Martinsson, ... Stem cells translational medicine 9 (1), 47-60, 2020 | 22 | 2020 |
Phenotypic screen for cardiac regeneration identifies molecules with differential activity in human epicardium-derived cells versus cardiac fibroblasts AI Paunovic, L Drowley, A Nordqvist, E Ericson, E Mouchet, A Jonebring, ... ACS Chemical Biology 12 (1), 132-141, 2017 | 21 | 2017 |
Differential expression of IGF-I and IGF-binding protein-1 and-2 in periportal and perivenous zones of rat liver SJ Hazel, ACS Nordqvist, K Hall, M Nilsson, M Schalling Journal of endocrinology 157 (2), 285-294, 1998 | 20 | 1998 |
Identification of mineralocorticoid receptor modulators with low impact on electrolyte homeostasis but maintained organ protection KL Granberg, ZQ Yuan, B Lindmark, K Edman, J Kajanus, A Hogner, ... Journal of Medicinal Chemistry 62 (3), 1385-1406, 2018 | 19 | 2018 |
Neuropeptide 26RFa (QRFP) is a key regulator of glucose homeostasis and its activity is markedly altered in obese/hyperglycemic mice G Prévost, A Arabo, MA Le Solliec, J Bons, M Picot, J Maucotel, ... American Journal of Physiology-Endocrinology and Metabolism 317 (1), E147-E157, 2019 | 17 | 2019 |
Microwave-enhanced α-arylation of a protected glycine in water: Evaluation of 3-phenylglycine derivatives as inhibitors of the tuberculosis enzyme, glutamine synthetase O Lagerlund, LR Odell, SL Mowbray, MT Nilsson, WW Krajewski, ... Combinatorial chemistry & high throughput screening 10 (9), 783-789, 2007 | 15 | 2007 |
Structure‐Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity A Nordqvist, G O'Mahony, M Fridén‐Saxin, M Fredenwall, A Hogner, ... ChemMedChem 12 (1), 50-65, 2017 | 13 | 2017 |
Structural characterization of agonist binding to protease-activated receptor 2 through mutagenesis and computational modeling AJ Kennedy, F Ballante, JR Johansson, G Milligan, L Sundström, ... ACS Pharmacology & Translational Science 1 (2), 119-133, 2018 | 10 | 2018 |
New hits as antagonists of GPR103 identified by HTS A Nordqvist, L Kristensson, KE Johansson, K Isaksson da Silva, T Fex, ... ACS Medicinal Chemistry Letters 5 (5), 527-532, 2014 | 9 | 2014 |
Predicting the relative binding affinity of mineralocorticoid receptor antagonists by density functional methods K Roos, A Hogner, D Ogg, MJ Packer, E Hansson, KL Granberg, ... Journal of computer-aided molecular design 29, 1109-1122, 2015 | 8 | 2015 |