|Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C (high) monocytes|
K Movahedi, D Laoui, C Gysemans, M Baeten, G Stangé, ...
Cancer research 70 (14), 5728-5739, 2010
|HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF|
C Rolny, M Mazzone, S Tugues, D Laoui, I Johansson, C Coulon, ...
Cancer cell 19 (1), 31-44, 2011
|Impeding macrophage entry into hypoxic tumor areas by Sema3A/Nrp1 signaling blockade inhibits angiogenesis and restores antitumor immunity|
A Casazza, D Laoui, M Wenes, S Rizzolio, N Bassani, M Mambretti, ...
Cancer cell 24 (6), 695-709, 2013
|Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population|
D Laoui, E Van Overmeire, G Di Conza, C Aldeni, J Keirsse, Y Morias, ...
Cancer research 74 (1), 24-30, 2014
|Tumor-associated macrophages in breast cancer: distinct subsets, distinct functions|
D Laoui, K Movahedi, E Van Overmeire, J Van den Bossche, E Schouppe, ...
International Journal of Developmental Biology 55 (7-8-9), 861-867, 2011
|Nanobody-based targeting of the macrophage mannose receptor for effective in vivo imaging of tumor-associated macrophages|
K Movahedi, S Schoonooghe, D Laoui, I Houbracken, W Waelput, ...
Cancer research 72 (16), 4165-4177, 2012
|Dual angiopoietin-2 and VEGFA inhibition elicits antitumor immunity that is enhanced by PD-1 checkpoint blockade|
M Schmittnaegel, N Rigamonti, E Kadioglu, A Cassará, CW Rmili, ...
Science translational medicine 9 (385), 2017
|Molecular profiling reveals a tumor-promoting phenotype of monocytes and macrophages in human cancer progression|
M Chittezhath, MK Dhillon, JY Lim, D Laoui, IN Shalova, YL Teo, J Chen, ...
Immunity 41 (5), 815-829, 2014
|Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity|
C Baer, ML Squadrito, D Laoui, D Thompson, SK Hansen, A Kiialainen, ...
Nature cell biology 18 (7), 790-802, 2016
|Functional relationship between tumor-associated macrophages and macrophage colony-stimulating factor as contributors to cancer progression|
D Laoui, E Van Overmeire, P De Baetselier, JA Van Ginderachter, G Raes
Frontiers in immunology 5, 489, 2014
|M-CSF and GM-CSF receptor signaling differentially regulate monocyte maturation and macrophage polarization in the tumor microenvironment|
E Van Overmeire, B Stijlemans, F Heymann, J Keirsse, Y Morias, Y Elkrim, ...
Cancer research 76 (1), 35-42, 2016
|Mechanisms driving macrophage diversity and specialization in distinct tumor microenvironments and parallelisms with other tissues|
E Van Overmeire, D Laoui, J Keirsse, JA Van Ginderachter, A Sarukhan
Frontiers in immunology 5, 127, 2014
|Tissue-resident versus monocyte-derived macrophages in the tumor microenvironment|
Q Lahmar, J Keirsse, D Laoui, K Movahedi, E Van Overmeire, ...
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1865 (1), 23-34, 2016
|The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity|
D Laoui, J Keirsse, Y Morias, E Van Overmeire, X Geeraerts, Y Elkrim, ...
Nature communications 7 (1), 1-17, 2016
|Mononuclear phagocyte heterogeneity in cancer: different subsets and activation states reaching out at the tumor site|
D Laoui, E Van Overmeire, K Movahedi, J Van den Bossche, E Schouppe, ...
Immunobiology 216 (11), 1192-1202, 2011
|PET imaging of macrophage mannose receptor–expressing macrophages in tumor stroma using 18F-radiolabeled camelid single-domain antibody fragments|
A Blykers, S Schoonooghe, C Xavier, K D’hoe, D Laoui, M D’Huyvetter, ...
Journal of Nuclear Medicine 56 (8), 1265-1271, 2015
|Myeloid cell heterogeneity in cancer: not a single cell alike|
M Kiss, S Van Gassen, K Movahedi, Y Saeys, D Laoui
Cellular Immunology 330, 188-201, 2018
|Tumor‐induced myeloid‐derived suppressor cell subsets exert either inhibitory or stimulatory effects on distinct CD8+ T‐cell activation events|
E Schouppe, C Mommer, K Movahedi, D Laoui, Y Morias, C Gysemans, ...
European journal of immunology 43 (11), 2930-2942, 2013
|In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities|
OM Pello, R Chevre, D Laoui, A De Juan, F Lolo, MJ Andrés-Manzano, ...
PloS one 7 (9), e45399, 2012
|Novel applications of nanobodies for in vivo bio-imaging of inflamed tissues in inflammatory diseases and cancer|
S Schoonooghe, D Laoui, JA Van Ginderachter, N Devoogdt, T Lahoutte, ...
Immunobiology 217 (12), 1266-1272, 2012