Olivier Lichtarge
Olivier Lichtarge
Professor of Molecular and Human Genetics, Baylor College of Medicine
Verified email at bcm.edu - Homepage
Cited by
Cited by
An evolutionary trace method defines binding surfaces common to protein families
O Lichtarge, HR Bourne, FE Cohen
Journal of molecular biology 257 (2), 342-358, 1996
Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma
CGAR Network
Cell 169 (7), 1327-1341, 2017
β-Arrestin-dependent, G protein-independent ERK1/2 activation by the β2 adrenergic receptor
SK Shenoy, MT Drake, CD Nelson, DA Houtz, K Xiao, S Madabushi, ...
Journal of Biological Chemistry 281 (2), 1261-1273, 2006
A large-scale evaluation of computational protein function prediction
P Radivojac, WT Clark, TR Oron, AM Schnoes, T Wittkop, A Sokolov, ...
Nature methods 10 (3), 221-227, 2013
Identification of a candidate therapeutic autophagy-inducing peptide
S Shoji-Kawata, R Sumpter, M Leveno, GR Campbell, Z Zou, L Kinch, ...
Nature 494 (7436), 201-206, 2013
Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F
SP Sheikh, TA Zvyaga, O Lichtarge, TP Sakmar, HR Bourne
nature 383 (6598), 347-350, 1996
Influence of mutation type and X chromosome inactivation on Rett syndrome phenotypes
RE Amir, IB Van Den Veyver, R Schultz, DM Malicki, CQ Tran, EJ Dahle, ...
Annals of neurology 47 (5), 670-679, 2000
A family of evolution–entropy hybrid methods for ranking protein residues by importance
I Mihalek, I Reš, O Lichtarge
Journal of molecular biology 336 (5), 1265-1282, 2004
Evolutionary predictions of binding surfaces and interactions
O Lichtarge, ME Sowa
Current opinion in structural biology 12 (1), 21-27, 2002
Pathogenic germline variants in 10,389 adult cancers
K Huang, RJ Mashl, Y Wu, DI Ritter, J Wang, C Oh, M Paczkowska, ...
Cell 173 (2), 355-370. e14, 2018
Receptor and βγ binding sites in the α subunit of the retinal G protein transducin
R Onrust, P Herzmark, P Chi, PD Garcia, O Lichtarge, C Kingsley, ...
Science 275 (5298), 381-384, 1997
Structural clusters of evolutionary trace residues are statistically significant and common in proteins
S Madabushi, H Yao, M Marsh, DM Kristensen, A Philippi, ME Sowa, ...
Journal of molecular biology 316 (1), 139-154, 2002
An accurate, sensitive, and scalable method to identify functional sites in protein structures
H Yao, DM Kristensen, I Mihalek, ME Sowa, C Shaw, M Kimmel, L Kavraki, ...
Journal of molecular biology 326 (1), 255-261, 2003
Similar structures and shared switch mechanisms of the β2-adrenoceptor and the parathyroid hormone receptor: Zn (II) bridges between helices III and VI block activation
SP Sheikh, JP Vilardarga, TJ Baranski, O Lichtarge, T Iiri, EC Meng, ...
Journal of Biological Chemistry 274 (24), 17033-17041, 1999
Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions
S Madabushi, AK Gross, A Philippi, EC Meng, TG Wensel, O Lichtarge
Journal of Biological Chemistry 279 (9), 8126-8132, 2004
Evolutionarily conserved Galphabetagamma binding surfaces support a model of the G protein-receptor complex
O Lichtarge, HR Bourne, FE Cohen
Proceedings of the National Academy of Sciences 93 (15), 7507-7511, 1996
An AT-hook domain in MeCP2 determines the clinical course of Rett syndrome and related disorders
SA Baker, L Chen, AD Wilkins, P Yu, O Lichtarge, HY Zoghbi
Cell 152 (5), 984-996, 2013
Identity and function of a large gene network underlying mutagenic repair of DNA breaks
AAM Al Mamun, MJ Lombardo, C Shee, AM Lisewski, C Gonzalez, D Lin, ...
Science 338 (6112), 1344-1348, 2012
Prediction and confirmation of a site critical for effector regulation of RGS domain activity
ME Sowa, W He, KC Slep, MA Kercher, O Lichtarge, TG Wensel
Nature structural biology 8 (3), 234-237, 2001
C5a receptor activation: genetic identification of critical residues in four transmembrane helices
TJ Baranski, P Herzmark, O Lichtarge, BO Gerber, J Trueheart, EC Meng, ...
Journal of Biological Chemistry 274 (22), 15757-15765, 1999
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