| An evolutionary trace method defines binding surfaces common to protein families O Lichtarge, HR Bourne, FE Cohen Journal of molecular biology 257 (2), 342-358, 1996 | 1356 | 1996 |
| Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma CGAR Network Cell 169 (7), 1327-1341, 2017 | 801 | 2017 |
| β-Arrestin-dependent, G protein-independent ERK1/2 activation by the β2 adrenergic receptor SK Shenoy, MT Drake, CD Nelson, DA Houtz, K Xiao, S Madabushi, ... Journal of Biological Chemistry 281 (2), 1261-1273, 2006 | 779 | 2006 |
| A large-scale evaluation of computational protein function prediction P Radivojac, WT Clark, TR Oron, AM Schnoes, T Wittkop, A Sokolov, ... Nature methods 10 (3), 221-227, 2013 | 761 | 2013 |
| Identification of a candidate therapeutic autophagy-inducing peptide S Shoji-Kawata, R Sumpter, M Leveno, GR Campbell, Z Zou, L Kinch, ... Nature 494 (7436), 201-206, 2013 | 583 | 2013 |
| Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F SP Sheikh, TA Zvyaga, O Lichtarge, TP Sakmar, HR Bourne nature 383 (6598), 347-350, 1996 | 467 | 1996 |
| Influence of mutation type and X chromosome inactivation on Rett syndrome phenotypes RE Amir, IB Van Den Veyver, R Schultz, DM Malicki, CQ Tran, EJ Dahle, ... Annals of neurology 47 (5), 670-679, 2000 | 385 | 2000 |
| A family of evolution–entropy hybrid methods for ranking protein residues by importance I Mihalek, I Reš, O Lichtarge Journal of molecular biology 336 (5), 1265-1282, 2004 | 307 | 2004 |
| Evolutionary predictions of binding surfaces and interactions O Lichtarge, ME Sowa Current opinion in structural biology 12 (1), 21-27, 2002 | 305 | 2002 |
| Pathogenic germline variants in 10,389 adult cancers K Huang, RJ Mashl, Y Wu, DI Ritter, J Wang, C Oh, M Paczkowska, ... Cell 173 (2), 355-370. e14, 2018 | 278 | 2018 |
| Receptor and βγ binding sites in the α subunit of the retinal G protein transducin R Onrust, P Herzmark, P Chi, PD Garcia, O Lichtarge, C Kingsley, ... Science 275 (5298), 381-384, 1997 | 249 | 1997 |
| Structural clusters of evolutionary trace residues are statistically significant and common in proteins S Madabushi, H Yao, M Marsh, DM Kristensen, A Philippi, ME Sowa, ... Journal of molecular biology 316 (1), 139-154, 2002 | 238 | 2002 |
| An accurate, sensitive, and scalable method to identify functional sites in protein structures H Yao, DM Kristensen, I Mihalek, ME Sowa, C Shaw, M Kimmel, L Kavraki, ... Journal of molecular biology 326 (1), 255-261, 2003 | 232 | 2003 |
| Similar structures and shared switch mechanisms of the β2-adrenoceptor and the parathyroid hormone receptor: Zn (II) bridges between helices III and VI block activation SP Sheikh, JP Vilardarga, TJ Baranski, O Lichtarge, T Iiri, EC Meng, ... Journal of Biological Chemistry 274 (24), 17033-17041, 1999 | 224 | 1999 |
| Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions S Madabushi, AK Gross, A Philippi, EC Meng, TG Wensel, O Lichtarge Journal of Biological Chemistry 279 (9), 8126-8132, 2004 | 209 | 2004 |
| Evolutionarily conserved Galphabetagamma binding surfaces support a model of the G protein-receptor complex O Lichtarge, HR Bourne, FE Cohen Proceedings of the National Academy of Sciences 93 (15), 7507-7511, 1996 | 205 | 1996 |
| An AT-hook domain in MeCP2 determines the clinical course of Rett syndrome and related disorders SA Baker, L Chen, AD Wilkins, P Yu, O Lichtarge, HY Zoghbi Cell 152 (5), 984-996, 2013 | 190 | 2013 |
| Identity and function of a large gene network underlying mutagenic repair of DNA breaks AAM Al Mamun, MJ Lombardo, C Shee, AM Lisewski, C Gonzalez, D Lin, ... Science 338 (6112), 1344-1348, 2012 | 171 | 2012 |
| Prediction and confirmation of a site critical for effector regulation of RGS domain activity ME Sowa, W He, KC Slep, MA Kercher, O Lichtarge, TG Wensel Nature structural biology 8 (3), 234-237, 2001 | 149 | 2001 |
| C5a receptor activation: genetic identification of critical residues in four transmembrane helices TJ Baranski, P Herzmark, O Lichtarge, BO Gerber, J Trueheart, EC Meng, ... Journal of Biological Chemistry 274 (22), 15757-15765, 1999 | 149 | 1999 |
Marek KimmelProfessor of Statistics and Bioengineering, Rice UniversityVerified email at rice.edu
