HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle MA Deardorff, M Bando, R Nakato, E Watrin, T Itoh, M Minamino, K Saitoh, ... Nature 489 (7415), 313-317, 2012 | 660 | 2012 |
A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine MD Ruben, G Wu, DF Smith, RE Schmidt, LJ Francey, YY Lee, RC Anafi, ... Science translational medicine 10 (458), eaat8806, 2018 | 276 | 2018 |
Guidelines for genome-scale analysis of biological rhythms ME Hughes, KC Abruzzi, R Allada, R Anafi, AB Arpat, G Asher, P Baldi, ... Journal of biological rhythms 32 (5), 380-393, 2017 | 249 | 2017 |
CYCLOPS reveals human transcriptional rhythms in health and disease RC Anafi, LJ Francey, JB Hogenesch, J Kim Proceedings of the National Academy of Sciences 114 (20), 5312-5317, 2017 | 227 | 2017 |
Clock regulation of metabolites reveals coupling between transcription and metabolism SY Krishnaiah, G Wu, BJ Altman, J Growe, SD Rhoades, F Coldren, ... Cell metabolism 25 (4), 961-974. e4, 2017 | 206 | 2017 |
Loss-of-function HDAC8 mutations cause a phenotypic spectrum of Cornelia de Lange syndrome-like features, ocular hypertelorism, large fontanelle and X-linked … FJ Kaiser, M Ansari, D Braunholz, M Concepción Gil-Rodríguez, ... Human molecular genetics 23 (11), 2888-2900, 2014 | 185 | 2014 |
Mechanistic insights into the events that lead to synergistic induction of interleukin 6 transcription upon activation of the aryl hydrocarbon receptor and inflammatory signaling BC DiNatale, JC Schroeder, LJ Francey, A Kusnadi, GH Perdew Journal of Biological Chemistry 285 (32), 24388-24397, 2010 | 139 | 2010 |
Population-level rhythms in human skin with implications for circadian medicine G Wu, MD Ruben, RE Schmidt, LJ Francey, DF Smith, RC Anafi, ... Proceedings of the National Academy of Sciences 115 (48), 12313-12318, 2018 | 125 | 2018 |
Genome‐wide SNP genotyping identifies the Stereocilin (STRC) gene as a major contributor to pediatric bilateral sensorineural hearing impairment LJ Francey, LK Conlin, HE Kadesch, D Clark, D Berrodin, Y Sun, ... American journal of medical genetics Part A 158 (2), 298-308, 2012 | 109 | 2012 |
Semaphorin 3d signaling defects are associated with anomalous pulmonary venous connections K Degenhardt, MK Singh, H Aghajanian, D Massera, Q Wang, J Li, L Li, ... Nature medicine 19 (6), 760-765, 2013 | 84 | 2013 |
Role for LSM genes in the regulation of circadian rhythms S Perez-Santángelo, E Mancini, LJ Francey, RG Schlaen, ... Proceedings of the National Academy of Sciences 111 (42), 15166-15171, 2014 | 75 | 2014 |
Computational and experimental insights into the circadian effects of SIRT1 PT Foteinou, A Venkataraman, LJ Francey, RC Anafi, JB Hogenesch, ... Proceedings of the National Academy of Sciences 115 (45), 11643-11648, 2018 | 64 | 2018 |
NF-κB modifies the mammalian circadian clock through interaction with the core clock protein BMAL1 Y Shen, M Endale, W Wang, AR Morris, LJ Francey, RL Harold, ... PLoS genetics 17 (11), e1009933, 2021 | 57 | 2021 |
KPNB1 mediates PER/CRY nuclear translocation and circadian clock function Y Lee, AR Jang, LJ Francey, A Sehgal, JB Hogenesch Elife 4, e08647, 2015 | 51 | 2015 |
A population-based gene expression signature of molecular clock phase from a single epidermal sample G Wu, MD Ruben, LJ Francey, DF Smith, JD Sherrill, JE Oblong, KJ Mills, ... Genome medicine 12, 1-12, 2020 | 46 | 2020 |
Novel COCH mutation in a family with autosomal dominant late onset sensorineural hearing impairment and tinnitus E Gallant, L Francey, H Fetting, M Kaur, H Hakonarson, D Clark, M Devoto, ... American journal of otolaryngology 34 (3), 230-235, 2013 | 40 | 2013 |
CRY1‐CBS binding regulates circadian clock function and metabolism S Cal‐Kayitmazbatir, E Kulkoyluoglu‐Cotul, J Growe, CP Selby, ... The FEBS journal 288 (2), 614-639, 2021 | 35 | 2021 |
A large-scale study reveals 24-h operational rhythms in hospital treatment MD Ruben, LJ Francey, Y Guo, G Wu, EB Cooper, AS Shah, ... Proceedings of the National Academy of Sciences 116 (42), 20953-20958, 2019 | 32 | 2019 |
The Local Edge Machine: inference of dynamic models of gene regulation KA McGoff, X Guo, A Deckard, CM Kelliher, AR Leman, LJ Francey, ... Genome biology 17, 1-13, 2016 | 32 | 2016 |
p53 Mutagenesis by Benzo[a]pyrene Derived Radical Cations S Sen, P Bhojnagarwala, L Francey, D Lu, TM Penning, J Field Chemical research in toxicology 25 (10), 2117-2126, 2012 | 32 | 2012 |