| Counting absolute numbers of molecules using unique molecular identifiers T Kivioja, A Vähärautio, K Karlsson, M Bonke, M Enge, S Linnarsson, ... Nature methods 9 (1), 72-74, 2012 | 1134 | 2012 |
| Regulation of the human p21 (waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D 3 receptor A Saramäki, CM Banwell, MJ Campbell, C Carlberg Nucleic acids research 34 (2), 543-554, 2006 | 294 | 2006 |
| Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors IK Sur, O Hallikas, A Vähärautio, J Yan, M Turunen, M Enge, M Taipale, ... Science 338 (6112), 1360-1363, 2012 | 229 | 2012 |
| The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera V Ahola, R Lehtonen, P Somervuo, L Salmela, P Koskinen, P Rastas, ... Nature communications 5 (1), 4737, 2014 | 212 | 2014 |
| Integrated data analysis reveals uterine leiomyoma subtypes with distinct driver pathways and biomarkers M Mehine, E Kaasinen, HR Heinonen, N Mäkinen, K Kämpjärvi, ... Proceedings of the National Academy of Sciences 113 (5), 1315-1320, 2016 | 182 | 2016 |
| Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity M Turunen, JM Spaeth, S Keskitalo, MJ Park, T Kivioja, AD Clark, ... Cell reports 7 (3), 654-660, 2014 | 150 | 2014 |
| Cyclical chromatin looping and transcription factor association on the regulatory regions of the p21 (CDKN1A) gene in response to 1α, 25-dihydroxyvitamin D3 A Saramaki, S Diermeier, R Kellner, H Laitinen, S Vaisanen, C Carlberg Journal of Biological Chemistry 284 (12), 8073-8082, 2009 | 119 | 2009 |
| A Functional Homologous Recombination Assay Predicts Primary Chemotherapy Response and Long-Term Survival in Ovarian Cancer PatientsFunctional HRD Predicts Clinical Outcome in … M Tumiati, S Hietanen, J Hynninen, E Pietilä, A Färkkilä, K Kaipio, ... Clinical Cancer Research 24 (18), 4482-4493, 2018 | 84 | 2018 |
| Distinct HDACs regulate the transcriptional response of human cyclin-dependent kinase inhibitor genes to trichostatin A and 1α,25-dihydroxyvitamin D 3 M Malinen, A Saramäki, A Ropponen, T Degenhardt, S Väisänen, ... Nucleic acids research 36 (1), 121-132, 2008 | 71 | 2008 |
| Identification of single nucleotide polymorphisms in the p21 (CDKN1A) gene and correlations with longevity in the Italian population IBR Silvia Gravina , Francesco Lescai , Gregory Hurteau , Graham J. Brock ... Aging (Albany NY) 1 (5), 470—480, 2009 | 39 | 2009 |
| Controlling the chromatin organization of vitamin D target genes by multiple vitamin D receptor binding sites C Carlberg, TW Dunlop, A Saramäki, L Sinkkonen, M Matilainen, ... The Journal of steroid biochemistry and molecular biology 103 (3-5), 338-343, 2007 | 38 | 2007 |
| Transcriptional networks controlling the cell cycle M Bonke, M Turunen, M Sokolova, A Vähärautio, T Kivioja, M Taipale, ... G3: Genes| Genomes| Genetics 3 (1), 75-90, 2013 | 32 | 2013 |
| Contribution of allelic imbalance to colorectal cancer K Palin, E Pitkänen, M Turunen, B Sahu, P Pihlajamaa, T Kivioja, ... Nature communications 9 (1), 3664, 2018 | 30 | 2018 |
| Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion M Sokolova, M Turunen, O Mortusewicz, T Kivioja, P Herr, A Vähärautio, ... Cell cycle 16 (2), 189-199, 2017 | 29 | 2017 |
| Cancer by super-enhancer A Vähärautio, J Taipale Science 346 (6215), 1291-1292, 2014 | 28 | 2014 |
| Longitudinal single-cell RNA-seq analysis reveals stress-promoted chemoresistance in metastatic ovarian cancer K Zhang, EP Erkan, S Jamalzadeh, J Dai, N Andersson, K Kaipio, ... Science advances 8 (8), eabm1831, 2022 | 25 | 2022 |
| miQC: An adaptive probabilistic framework for quality control of single-cell RNA-sequencing data AA Hippen, MM Falco, LM Weber, EP Erkan, K Zhang, JA Doherty, ... PLOS Computational Biology 17 (8), e1009290, 2021 | 20 | 2021 |
| PRISM: recovering cell-type-specific expression profiles from individual composite RNA-seq samples A Häkkinen, K Zhang, A Alkodsi, N Andersson, EP Erkan, J Dai, K Kaipio, ... Bioinformatics 37 (18), 2882-2888, 2021 | 10 | 2021 |
| Network-guided identification of cancer-selective combinatorial therapies in ovarian cancer L He, D Bulanova, J Oikkonen, A Häkkinen, K Zhang, S Zheng, W Wang, ... Briefings in bioinformatics 22 (6), bbab272, 2021 | 9 | 2021 |
| Upregulation of ribosome biogenesis via canonical E-boxes is required for Myc-driven proliferation N Zielke, A Vähärautio, J Liu, T Kivioja, J Taipale Developmental Cell 57 (8), 1024-1036. e5, 2022 | 3 | 2022 |
Jussi TaipaleUniversity of Cambridge, Department of BiochemistryVerified email at cam.ac.uk
