| Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors EJ Morris, S Jha, CR Restaino, P Dayananth, H Zhu, A Cooper, D Carr, ... Cancer discovery 3 (7), 742-750, 2013 | 711 | 2013 |
| Filopodia are required for cortical neurite initiation EW Dent, AV Kwiatkowski, LM Mebane, U Philippar, M Barzik, ... Nature cell biology 9 (12), 1347-1359, 2007 | 366 | 2007 |
| A Mena invasion isoform potentiates EGF-induced carcinoma cell invasion and metastasis U Philippar, ET Roussos, M Oser, H Yamaguchi, HD Kim, S Giampieri, ... Developmental cell 15 (6), 813-828, 2008 | 338 | 2008 |
| Ena/VASP Is Required for neuritogenesis in the developing cortex AV Kwiatkowski, DA Rubinson, EW Dent, JE Van Veen, JD Leslie, ... Neuron 56 (3), 441-455, 2007 | 263 | 2007 |
| Serum response factor is crucial for actin cytoskeletal organization and focal adhesion assembly in embryonic stem cells G Schratt, U Philippar, J Berger, H Schwarz, O Heidenreich, A Nordheim The Journal of cell biology 156 (4), 737-750, 2002 | 252 | 2002 |
| The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF U Philippar, G Schratt, C Dieterich, JM Müller, P Galgóczy, FB Engel, ... Molecular cell 16 (6), 867-880, 2004 | 193 | 2004 |
| Neuronal migration in the murine rostral migratory stream requires serum response factor S Alberti, SM Krause, O Kretz, U Philippar, T Lemberger, E Casanova, ... Proceedings of the National Academy of Sciences 102 (17), 6148-6153, 2005 | 181 | 2005 |
| Simultaneous imaging of GFP, CFP and collagen in tumors in vivousing multiphoton microscopy E Sahai, J Wyckoff, U Philippar, JE Segall, F Gertler, J Condeelis BMC biotechnology 5, 1-9, 2005 | 174 | 2005 |
| DLK1-DIO3 genomic imprinted microRNA cluster at 14q32. 2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival JM Luk, J Burchard, C Zhang, AM Liu, KF Wong, FH Shek, NP Lee, ... Journal of Biological Chemistry 286 (35), 30706-30713, 2011 | 173 | 2011 |
| Identification of invasion specific splice variants of the cytoskeletal protein Mena present in mammary tumor cells during invasion in vivo S Goswami, U Philippar, D Sun, A Patsialou, J Avraham, W Wang, ... Clinical & experimental metastasis 26, 153-159, 2009 | 156 | 2009 |
| SRF regulates Bcl‐2 expression and promotes cell survival during murine embryonic development G Schratt, U Philippar, D Hockemeyer, H Schwarz, S Alberti, A Nordheim The EMBO journal 23 (8), 1834-1844, 2004 | 95 | 2004 |
| Human Mena+ 11a isoform serves as a marker of epithelial phenotype and sensitivity to epidermal growth factor receptor inhibition in human pancreatic cancer cell lines MS Pino, M Balsamo, F Di Modugno, M Mottolese, M Alessio, E Melucci, ... Clinical Cancer Research 14 (15), 4943-4950, 2008 | 86 | 2008 |
| Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting JR Lamb, C Zhang, T Xie, K Wang, B Zhang, K Hao, E Chudin, HB Fraser, ... PloS one 6 (7), e20090, 2011 | 66 | 2011 |
| Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth L Fontán, Q Qiao, JM Hatcher, G Casalena, I Us, M Teater, M Durant, ... The Journal of clinical investigation 128 (10), 4397-4412, 2018 | 58 | 2018 |
| Discovery and pharmacological characterization of JNJ-64619178, a novel small-molecule inhibitor of PRMT5 with potent antitumor activity D Brehmer, L Beke, T Wu, HJ Millar, C Moy, W Sun, G Mannens, V Pande, ... Molecular cancer therapeutics 20 (12), 2317-2328, 2021 | 55 | 2021 |
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| Assessing IRAK4 functions in ABC DLBCL by IRAK4 kinase inhibition and protein degradation J Zhang, L Fu, B Shen, Y Liu, W Wang, X Cai, L Kong, Y Yan, R Meng, ... Cell Chemical Biology 27 (12), 1500-1509. e13, 2020 | 39 | 2020 |
| PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena SK Hughes, MJ Oudin, J Tadros, J Neil, A Del Rosario, BA Joughin, ... Molecular biology of the cell 26 (21), 3867-3878, 2015 | 39 | 2015 |
| Discovery of 1-(1H-Pyrazolo[4,3-c]pyridin-6-yl)urea Inhibitors of Extracellular Signal-Regulated Kinase (ERK) for the Treatment of Cancers J Lim, EH Kelley, JL Methot, H Zhou, A Petrocchi, H Chen, SE Hill, ... Journal of medicinal chemistry 59 (13), 6501-6511, 2016 | 38 | 2016 |
| Gene signatures derived from a c-MET-driven liver cancer mouse model predict survival of patients with hepatocellular carcinoma I Ivanovska, C Zhang, AM Liu, KF Wong, NP Lee, P Lewis, U Philippar, ... PLoS One 6 (9), e24582, 2011 | 34 | 2011 |
