Differences in active site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase A Saxena, AMG Redman, X Jiang, O Lockridge, BP Doctor Biochemistry 36 (48), 14642-14651, 1997 | 370 | 1997 |
Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor X Jiang, H Liu, X Chen, PH Chen, D Fischer, V Sriraman, HN Yu, ... Proceedings of the National Academy of Sciences 109 (31), 12491-12496, 2012 | 286 | 2012 |
Crystal structure of inhibitor of κB kinase β G Xu, YC Lo, Q Li, G Napolitano, X Wu, X Jiang, M Dreano, M Karin, H Wu Nature 472 (7343), 325, 2011 | 237 | 2011 |
Structural predictions for the ligand-binding region of glycoprotein hormone receptors and the nature of hormone–receptor interactions X Jiang, M Dreano, DR Buckler, S Cheng, A Ythier, H Wu, ... Structure 3 (12), 1341-1353, 1995 | 221 | 1995 |
Structural biology of glycoprotein hormones and their receptors: insights to signaling X Jiang, JA Dias, X He Molecular and cellular endocrinology 382 (1), 424-451, 2014 | 220 | 2014 |
Main‐chain conformational tendencies of amino acids RJ Anderson, Z Weng, RK Campbell, X Jiang Proteins: Structure, Function, and Bioinformatics 60 (4), 679-689, 2005 | 176 | 2005 |
Structure of the active core of human stem cell factor and analysis of binding to its receptor kit X Jiang, O Gurel, EA Mendiaz, GW Stearns, CL Clogston, HS Lu, ... The EMBO journal 19 (13), 3192, 2000 | 137 | 2000 |
Evidence for follicle-stimulating hormone receptor as a functional trimer X Jiang, D Fischer, X Chen, SD McKenna, H Liu, V Sriraman, NY Henry, ... Journal of Biological Chemistry 289 (20), 14273-14282, 2014 | 91 | 2014 |
Design, synthesis, and biological activity of novel, potent, and selective (benzoylaminomethyl)thiophene sulfonamide inhibitors of c-Jun-N-terminal kinase. T Rueckle, M Biamonte, T Grippi-Vallotton, S Arkinstall, Y Cambet, ... Journal of Medicinal Chemistry 47 (27), 6921-34, 2004 | 75 | 2004 |
Stoichiometry of heteromeric BAFF and APRIL cytokines dictates their receptor binding and signaling properties S Schuepbach-Mallepell, D Das, L Willen, M Vigolo, A Tardivel, L Lebon, ... Journal of Biological Chemistry 290 (26), 16330-16342, 2015 | 53 | 2015 |
A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors M Vigolo, MG Chambers, L Willen, D Chevalley, K Maskos, A Lammens, ... Nature communications 9 (1), 1199, 2018 | 39 | 2018 |
Discovery of novel Cyclophilin D inhibitors starting from three dimensional fragments with millimolar potencies U Grädler, D Schwarz, M Blaesse, B Leuthner, TL Johnson, F Bernard, ... Bioorganic & Medicinal Chemistry Letters 29 (23), 126717, 2019 | 34 | 2019 |
Structure-expression relationship of tumor necrosis factor receptor mutants that increase expression RL Schweickhardt, X Jiang, LM Garone, WH Brondyk Journal of Biological Chemistry 278 (31), 28961-28967, 2003 | 31 | 2003 |
Epitope characterization of an anti‐PD‐L1 antibody using orthogonal approaches G Hao, JS Wesolowski, X Jiang, S Lauder, VD Sood Journal of Molecular Recognition 28 (4), 269-276, 2015 | 30 | 2015 |
Discovery of substituted benzamides as follicle stimulating hormone receptor allosteric modulators NY Henry, TE Richardson, S Nataraja, DJ Fischer, V Sriraman, X Jiang, ... Bioorganic & medicinal chemistry letters 24 (9), 2168-2172, 2014 | 28 | 2014 |
Azolidinone-vinyl fused-benzene derivatives T Rueckle, X Jiang, P Gaillard, D Church, TG Vallotton, M Serono SA, ... US Patent 7,846,925, 2010 | 28 | 2010 |
3-arylamino pyridine derivatives U Abel, H Deppe, A Feurer, U Grädler, K Otte, R Sekul, M Thiemann, ... US Patent 7,956,191, 2011 | 22 | 2011 |
Macrocyclics pyrimidines as aurora kinase inhibitors H Yu, LC De Selm, X Jiang, BC Askew Jr, SR Karra, A Goutopoulos US Patent 8,815,872, 2014 | 20 | 2014 |
SAR and evaluation of novel 5H-benzo [c][1, 8] naphthyridin-6-one analogs as Aurora kinase inhibitors S Karra, Y Xiao, X Chen, L Liu-Bujalski, B Huck, A Sutton, A Goutopoulos, ... Bioorganic & medicinal chemistry letters 23 (10), 3081-3087, 2013 | 20 | 2013 |
Building protein backbones from Cα co-ordinates Y Luo, X Jiang, L Lai, C Qu, X Xu, Y Tang Protein Engineering, Design and Selection 5 (2), 147-150, 1992 | 20 | 1992 |