| Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors K Appleton, HJ Mackay, I Judson, JA Plumb, C McCormick, G Strathdee, ... Journal of Clinical Oncology 25 (29), 4603-4609, 2007 | 262 | 2007 |
| Primary ovarian carcinomas display multiple methylator phenotypes involving known tumor suppressor genes G Strathdee, K Appleton, M Illand, DWM Millan, J Sargent, J Paul, ... The American journal of pathology 158 (3), 1121-1127, 2001 | 249 | 2001 |
| A randomised, phase II trial of the DNA-hypomethylating agent 5-aza-2′-deoxycytidine (decitabine) in combination with carboplatin vs carboplatin alone in … RM Glasspool, R Brown, ME Gore, GJS Rustin, IA McNeish, RH Wilson, ... British journal of cancer 110 (8), 1923-1929, 2014 | 119 | 2014 |
| Comparison of behavioural activation with guided self-help for treatment of depression in adults with intellectual disabilities: a randomised controlled trial A Jahoda, R Hastings, C Hatton, SA Cooper, D Dagnan, R Zhang, ... The Lancet Psychiatry 4 (12), 909-919, 2017 | 73 | 2017 |
| Supporting people with intellectual disabilities in psychological therapies for depression: A qualitative analysis of supporters’ experiences K Scott, C Hatton, R Knight, K Singer, D Knowles, D Dagnan, RP Hastings, ... Journal of Applied Research in Intellectual Disabilities 32 (2), 323-335, 2019 | 13 | 2019 |
| Pyrosequencing of DNA extracted from formalin-fixed paraffin-embedded tissue B Doyle, C O’Riain, K Appleton Formalin-Fixed Paraffin-Embedded Tissues: Methods and Protocols, 181-190, 2011 | 12 | 2011 |
| “Getting into it”: People with intellectual disabilities’ experiences and views of Behavioural Activation and Guided Self‐Help for depression R Knight, A Jahoda, K Scott, K Sanger, D Knowles, D Dagnan, ... Journal of Applied Research in Intellectual Disabilities 32 (4), 819-830, 2019 | 11 | 2019 |
| Behavioural activation versus guided self-help for depression in adults with learning disabilities: the BeatIt RCT. A Jahoda, R Hastings, C Hatton, SA Cooper, N McMeekin, D Dagnan, ... Health Technology Assessment 22 (53), 1-130, 2018 | 11 | 2018 |
| A phase I trial of the DNA-hypomethylating agent 5-Aza-2'-Deoxycytidine in combination with carboplatin both given 4 weekly by intravenous injection in patients with advanced … C Lee, K Appleton, J Plumb, S Kaye, C Cruickshank, C Twelves, P Vasey, ... Journal of Clinical Oncology 22 (14_suppl), 2005-2005, 2004 | 6 | 2004 |
| Pharmacodynamic responses to 2'-deoxy-5-azacytidine in mice and humans K Appleton, JA Plumb, D Stuart, H Mackay, G Strathdee, M Luscome, ... Proc Am Assoc Cancer Res 44, 803-4, 2003 | 6 | 2003 |
| The experiences of therapists providing psychological treatment for adults with depression and intellectual disabilities as part of a randomised controlled trial IC Smith, JC Huws, K Appleton, SA Cooper, D Dagnan, RP Hastings, ... Journal of Applied Research in Intellectual Disabilities 34 (6), 1442-1451, 2021 | 4 | 2021 |
| Pharmacodynamic effects in patients treated with 6 hour infusion of the demethylating agent 5-aza-2'deoxycytidine (decitabine) R Brown, K Appleton, JA Plumb, C McCormick, C Lee, S Barrett, A Tang, ... Clinical Cancer Research 11 (24), 9071S-9072S, 2005 | 2 | 2005 |
| Phase I trial of the DNA hypomethylating agent 5-aza-2'deoxycytidine (decitabine) in combination with carboplatin both given 4-weekly by intravenous injection in patients with … SV Barrett, CP Lee, KJ Appleton, S Reade, D Jadayel, K Bellenger, ... CLINICAL CANCER RESEARCH 11 (24), 9058S-9058S, 2005 | 1 | 2005 |
| Predictors and moderators of the response of adults with intellectual disabilities and depression to behavioural activation and guided self‐help therapies CA Melville, C Hatton, E Beer, RP Hastings, SA Cooper, N McMeekin, ... Journal of Intellectual Disability Research 67 (10), 986-1002, 2023 | | 2023 |
| Economic evaluation A Jahoda, R Hastings, C Hatton, SA Cooper, N McMeekin, D Dagnan, ... Behavioural activation versus guided self-help for depression in adults with …, 2018 | | 2018 |
| Trial design and methods A Jahoda, R Hastings, C Hatton, SA Cooper, N McMeekin, D Dagnan, ... Behavioural activation versus guided self-help for depression in adults with …, 2018 | | 2018 |
| Detection of methylation at hMLH1 by fluorescent methylation specific PCR (F-MSP) in a Phase II trial of the demethylating agent decitabine in combination with carboplatin K Appleton, A Setanoians, C McCormick, R Ullah, R Brown, J Evans | | 2008 |
| Implementation of Good Clinical Laboratory Practice (GCLP) in Translational Research R Ullah, K Appleton, R Blackie, C McCormick, A Setanoians, J Evans | | 2007 |
| The pharmodynamic effects of decitabine in combination with carboplatin: results from a phase 1 clinical trial K Appleton, H Mackay, I Judson, J Plumb, C McCormick | | 2007 |
| Pharmacodynamic analysis of the DNA methyltransferase inhibitor decitabine in patient tissues KJ Appleton PQDT-Global, 2005 | | 2005 |
