Defined engineered human myocardium with advanced maturation for applications in heart failure modeling and repair M Tiburcy, JE Hudson, P Balfanz, S Schlick, T Meyer, ML Chang Liao, ... Circulation 135 (19), 1832-1847, 2017 | 563 | 2017 |
Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest RJ Mills, DM Titmarsh, X Koenig, BL Parker, JG Ryall, GA Quaife-Ryan, ... Proceedings of the National Academy of Sciences 114 (40), E8372-E8381, 2017 | 417 | 2017 |
Enhanced chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells in low oxygen environment micropellet cultures BD Markway, GK Tan, G Brooke, JE Hudson, JJ Cooper-White, MR Doran Cell transplantation 19 (1), 29-42, 2010 | 273 | 2010 |
Multicellular transcriptional analysis of mammalian heart regeneration GA Quaife-Ryan, CB Sim, M Ziemann, A Kaspi, H Rafehi, M Ramialison, ... Circulation 136 (12), 1123-1139, 2017 | 241 | 2017 |
Drug screening in human PSC-cardiac organoids identifies pro-proliferative compounds acting via the mevalonate pathway RJ Mills, BL Parker, GA Quaife-Ryan, HK Voges, EJ Needham, A Bornot, ... Cell stem cell 24 (6), 895-907. e6, 2019 | 236 | 2019 |
Single-cell transcriptomic analysis of cardiac differentiation from human PSCs reveals HOPX-dependent cardiomyocyte maturation CE Friedman, Q Nguyen, SW Lukowski, A Helfer, HS Chiu, J Miklas, ... Cell stem cell 23 (4), 586-598. e8, 2018 | 225 | 2018 |
Tailored integrin–extracellular matrix interactions to direct human mesenchymal stem cell differentiation JE Frith, RJ Mills, JE Hudson, JJ Cooper-White Stem cells and development 21 (13), 2442-2456, 2012 | 210 | 2012 |
Development of a human cardiac organoid injury model reveals innate regenerative potential HK Voges, RJ Mills, DA Elliott, RG Parton, ER Porrello, JE Hudson Development 144 (6), 1118-1127, 2017 | 199 | 2017 |
Neutrophil-derived S100A8/A9 amplify granulopoiesis after myocardial infarction G Sreejit, A Abdel-Latif, B Athmanathan, R Annabathula, A Dhyani, ... Circulation 141 (13), 1080-1094, 2020 | 177 | 2020 |
BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection RJ Mills, SJ Humphrey, PRJ Fortuna, M Lor, SR Foster, GA Quaife-Ryan, ... Cell 184 (8), 2167-2182. e22, 2021 | 138 | 2021 |
Evolution, comparative biology and ontogeny of vertebrate heart regeneration CJ Vivien, JE Hudson, ER Porrello NPJ Regenerative medicine 1 (1), 1-14, 2016 | 120 | 2016 |
Primitive cardiac cells from human embryonic stem cells J Hudson, D Titmarsh, A Hidalgo, E Wolvetang, J Cooper-White Stem cells and development 21 (9), 1513-1523, 2012 | 119 | 2012 |
NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network DJ Anderson, DI Kaplan, KM Bell, K Koutsis, JM Haynes, RJ Mills, ... Nature communications 9 (1), 1373, 2018 | 105 | 2018 |
Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids MP Zafeiriou, G Bao, J Hudson, R Halder, A Blenkle, MK Schreiber, ... Nature communications 11 (1), 3791, 2020 | 93 | 2020 |
Dynamic changes in the cardiac methylome during postnatal development CB Sim, M Ziemann, A Kaspi, KN Harikrishnan, J Ooi, I Khurana, L Chang, ... The FASEB Journal 29 (4), 1329-1343, 2015 | 72 | 2015 |
Induction of human iPSC-derived cardiomyocyte proliferation revealed by combinatorial screening in high density microbioreactor arrays DM Titmarsh, NR Glass, RJ Mills, A Hidalgo, EJ Wolvetang, ER Porrello, ... Scientific reports 6 (1), 24637, 2016 | 62 | 2016 |
Microbioreactor arrays for full factorial screening of exogenous and paracrine factors in human embryonic stem cell differentiation DM Titmarsh, JE Hudson, A Hidalgo, AG Elefanty, EG Stanley, ... PloS one 7 (12), e52405, 2012 | 53 | 2012 |
A defined medium and substrate for expansion of human mesenchymal stromal cell progenitors that enriches for osteo-and chondrogenic precursors JE Hudson, RJ Mills, JE Frith, G Brooke, P Jaramillo-Ferrada, ... Stem cells and development 20 (1), 77-87, 2011 | 53 | 2011 |
Platelet-derived growth factor-AB improves scar mechanics and vascularity after myocardial infarction S Thavapalachandran, SM Grieve, RD Hume, TYL Le, K Raguram, ... Science translational medicine 12 (524), eaay2140, 2020 | 52 | 2020 |
Bioengineering adult human heart tissue: How close are we? RJ Mills, JE Hudson APL bioengineering 3 (1), 2019 | 50 | 2019 |