| A genome-wide association study identifies IL23R as an inflammatory bowel disease gene RH Duerr, KD Taylor, SR Brant, JD Rioux, MS Silverberg, MJ Daly, ... science 314 (5804), 1461-1463, 2006 | 3753 | 2006 |
| Strong association of de novo copy number mutations with autism J Sebat, B Lakshmi, D Malhotra, J Troge, C Lese-Martin, T Walsh, ... Science 316 (5823), 445-449, 2007 | 3429 | 2007 |
| The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis PK Gregersen, J Silver, RJ Winchester Arthritis & Rheumatism 30 (11), 1205-1213, 1987 | 3272 | 1987 |
| Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus EC Baechler, FM Batliwalla, G Karypis, PM Gaffney, WA Ortmann, ... Proceedings of the National Academy of Sciences 100 (5), 2610-2615, 2003 | 2543 | 2003 |
| Genetics of rheumatoid arthritis contributes to biology and drug discovery Y Okada, D Wu, G Trynka, T Raj, C Terao, K Ikari, Y Kochi, K Ohmura, ... Nature 506 (7488), 376-381, 2014 | 2423 | 2014 |
| A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis AB Begovich, VEH Carlton, LA Honigberg, SJ Schrodi, AP Chokkalingam, ... The American Journal of Human Genetics 75 (2), 330-337, 2004 | 1874 | 2004 |
| Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci EA Stahl, S Raychaudhuri, EF Remmers, G Xie, S Eyre, BP Thomson, Y Li, ... Nature genetics 42 (6), 508-514, 2010 | 1557 | 2010 |
| Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci International Consortium for Systemic Lupus Erythematosus Genetics (SLEGEN) Nature genetics 40 (2), 204-210, 2008 | 1445 | 2008 |
| STAT4 and the Risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus EF Remmers, RM Plenge, AT Lee, RR Graham, G Hom, TW Behrens, ... New England Journal of Medicine 357 (10), 977-986, 2007 | 1309 | 2007 |
| Association of systemic lupus erythematosus with C8orf13–BLK and ITGAM–ITGAX G Hom, RR Graham, B Modrek, KE Taylor, W Ortmann, S Garnier, AT Lee, ... New England Journal of Medicine 358 (9), 900-909, 2008 | 1102 | 2008 |
| Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis S Raychaudhuri, C Sandor, EA Stahl, J Freudenberg, HS Lee, X Jia, ... Nature genetics 44 (3), 291-296, 2012 | 1042 | 2012 |
| TRAF1–C5 as a risk locus for rheumatoid arthritis—a genomewide study RM Plenge, M Seielstad, L Padyukov, AT Lee, EF Remmers, B Ding, ... New England Journal of Medicine 357 (12), 1199-1209, 2007 | 1038 | 2007 |
| An autoinflammatory disease with deficiency of the interleukin-1–receptor antagonist I Aksentijevich, SL Masters, PJ Ferguson, P Dancey, J Frenkel, ... New England Journal of Medicine 360 (23), 2426-2437, 2009 | 1036 | 2009 |
| A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus V Gateva, JK Sandling, G Hom, KE Taylor, SA Chung, X Sun, W Ortmann, ... Nature genetics 41 (11), 1228-1233, 2009 | 931 | 2009 |
| Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry F Zhang, K Wei, K Slowikowski, CY Fonseka, DA Rao, S Kelly, ... Nature immunology 20 (7), 928-942, 2019 | 858 | 2019 |
| Genome-wide association study in alopecia areata implicates both innate and adaptive immunity L Petukhova, M Duvic, M Hordinsky, D Norris, V Price, Y Shimomura, ... Nature 466 (7302), 113-117, 2010 | 852 | 2010 |
| Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE C Kyogoku, WA Ortmann, A Lee, S Selby, VEH Carlton, M Chang, ... The American Journal of Human Genetics 75 (3), 504-507, 2004 | 808 | 2004 |
| Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA–DRB1 shared epitope for antibodies to citrullinated proteins TWJ Huizinga, CI Amos, AHM van der Helm‐van Mil, W Chen, ... Arthritis & Rheumatism 52 (11), 3433-3438, 2005 | 778 | 2005 |
| Human polymorphism at microRNAs and microRNA target sites MA Saunders, H Liang, WH Li Proceedings of the National Academy of Sciences 104 (9), 3300-3305, 2007 | 775 | 2007 |
| High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis S Eyre, J Bowes, D Diogo, A Lee, A Barton, P Martin, A Zhernakova, ... Nature genetics 44 (12), 1336-1340, 2012 | 747 | 2012 |
