| Treatment-induced tumor dormancy through YAP-mediated transcriptional reprogramming of the apoptotic pathway KJ Kurppa, Y Liu, C To, T Zhang, M Fan, A Vajdi, EH Knelson, Y Xie, ... Cancer cell 37 (1), 104-122. e12, 2020 | 322 | 2020 |
| Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis AI Nieminen, VM Eskelinen, HM Haikala, TA Tervonen, Y Yan, ... Proceedings of the National Academy of Sciences 110 (20), E1839-E1848, 2013 | 156 | 2013 |
| Thirty years of HER3: from basic biology to therapeutic interventions HM Haikala, PA Jänne Clinical Cancer Research 27 (13), 3528-3539, 2021 | 78 | 2021 |
| An allosteric inhibitor against the therapy-resistant mutant forms of EGFR in non-small cell lung cancer C To, TS Beyett, J Jang, WW Feng, M Bahcall, HM Haikala, BH Shin, ... Nature cancer 3 (4), 402-417, 2022 | 71 | 2022 |
| Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy HM Haikala, JM Anttila, E Marques, T Raatikainen, M Ilander, H Hakanen, ... Nature communications 10 (1), 620, 2019 | 70 | 2019 |
| UBR5 is coamplified with MYC in breast tumors and encodes an ubiquitin ligase that limits MYC-dependent apoptosis X Qiao, Y Liu, ML Prada, AK Mohan, A Gupta, A Jaiswal, M Sharma, ... Cancer research 80 (7), 1414-1427, 2020 | 47 | 2020 |
| Repression of SRF target genes is critical for M yc‐dependent apoptosis of epithelial cells KE Wiese, HM Haikala, B von Eyss, E Wolf, C Esnault, A Rosenwald, ... The EMBO journal 34 (11), 1554-1571, 2015 | 39 | 2015 |
| EGFR Inhibition Enhances the Cellular Uptake and Antitumor-Activity of the HER3 Antibody–Drug Conjugate HER3–DXd HM Haikala, T Lopez, J Köhler, PO Eser, M Xu, Q Zeng, TJ Teceno, K Ngo, ... Cancer research 82 (1), 130-141, 2022 | 33 | 2022 |
| Comparative Analysis and Isoform-Specific Therapeutic Vulnerabilities of KRAS Mutations in Non–Small Cell Lung Cancer B Ricciuti, J Son, JJ Okoro, A Mira, E Patrucco, Y Eum, X Wang, R Paranal, ... Clinical Cancer Research 28 (8), 1640-1650, 2022 | 29 | 2022 |
| MYC and AMPK–save energy or die! HM Haikala, JM Anttila, J Klefström Frontiers in cell and developmental biology 5, 38, 2017 | 29 | 2017 |
| A Novel HER2-Selective Kinase Inhibitor Is Effective in HER2 Mutant and Amplified Non–Small Cell Lung Cancer J Son, J Jang, TS Beyett, Y Eum, HM Haikala, A Verano, M Lin, ... Cancer research 82 (8), 1633-1645, 2022 | 20 | 2022 |
| Myc requires RhoA/SRF to reprogram glutamine metabolism HM Haikala, E Marques, M Turunen, J Klefström Small GTPases 9 (3), 274-282, 2018 | 18 | 2018 |
| Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR-mutant lung cancer PÖ Eser, RM Paranal, J Son, E Ivanova, Y Kuang, HM Haikala, C To, ... Science translational medicine 13 (609), eabb3738, 2021 | 14 | 2021 |
| Sortilin‐related receptor is a druggable therapeutic target in breast cancer H Al‐Akhrass, M Pietilä, J Lilja, EM Vesilahti, JM Anttila, HM Haikala, ... Molecular oncology 16 (1), 116-129, 2022 | 8 | 2022 |
| EGFR inhibition enhances the cellular uptake and antitumor activity of the novel HER3 antibody drug conjugate U3-1402 HM Haikala, J Köhler, T Lopez, P Eser, M Xu, C Yu, Y Shiose, Y Qiu, ... Cancer Research 80 (16_Supplement), 5192-5192, 2020 | 6 | 2020 |
| Allosteric inhibition of drug resistant forms of EGFR L858R mutant NSCLC C To, TS Beyett, J Jang, WW Feng, M Bahcall, HM Haikala, BH Shin, ... Nature cancer 3 (4), 402, 2022 | 4 | 2022 |
| MYC-induced apoptosis in mammary epithelial cells is associated with repression of lineage-specific gene signatures HM Haikala, J Klefström, M Eilers, KE Wiese Cell Cycle 15 (3), 316-323, 2016 | 4 | 2016 |
| Switch to MET oncogene dependence as a novel mechanism of drug resistance in EGFR-mutant lung cancer PÖ Eser, RM Paranal, MJ Poitras, M Xu, S Wang, A Ogino, J Choi, ... Cancer Research 79 (13_Supplement), 1732-1732, 2019 | 2 | 2019 |
| Inhibition of CDK12 elevates cancer cell dependence on P-TEFb by stimulation of RNA polymerase II pause release Z Wang, SV Himanen, HM Haikala, CC Friedel, A Vihervaara, M Barborič Nucleic Acids Research 51 (20), 10970-10991, 2023 | 1 | 2023 |
| Publisher Correction: Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy HM Haikala, JM Anttila, E Marques, T Raatikainen, M Ilander, H Hakanen, ... Nature communications 10 (1), 932-932, 2019 | 1 | 2019 |
