Safety, pharmacokinetics and antiviral activity of PGT121, a broadly neutralizing monoclonal antibody against HIV-1: a randomized, placebo-controlled, phase 1 clinical trial KE Stephenson, B Julg, CS Tan, R Zash, SR Walsh, CP Rolle, ... Nature medicine 27 (10), 1718-1724, 2021 | 58 | 2021 |
Determinants of combination GM-CSF immunotherapy and oncolytic virotherapy success identified through in silico treatment personalization T Cassidy, M Craig PLoS computational biology 15 (11), e1007495, 2019 | 58 | 2019 |
In silico trials predict that combination strategies for enhancing vesicular stomatitis oncolytic virus are determined by tumor aggressivity AL Jenner, T Cassidy, K Belaid, MC Bourgeois-Daigneault, M Craig Journal for immunotherapy of cancer 9 (2), 2021 | 34 | 2021 |
Equivalences between age structured models and state dependent distributed delay differential equations T Cassidy, M Craig, AR Humphries Mathematical Biosciences and Engineering 16 (5), 5419-5450, 2019 | 28* | 2019 |
Transit and lifespan in neutrophil production: implications for drug intervention D Câmara De Souza, M Craig, T Cassidy, J Li, F Nekka, J Bélair, ... Journal of pharmacokinetics and pharmacodynamics 45, 59-77, 2018 | 27 | 2018 |
A simple model of COVID-19 explains disease severity and the effect of treatments S Sanche, T Cassidy, P Chu, AS Perelson, RM Ribeiro, R Ke Scientific Reports 12 (1), 14210, 2022 | 21 | 2022 |
The role of memory in non-genetic inheritance and its impact on cancer treatment resistance T Cassidy, D Nichol, M Robertson-Tessi, M Craig, ARA Anderson PLOS Computational Biology 17 (8), e1009348, 2021 | 20 | 2021 |
A mathematical model of viral oncology as an immuno-oncology instigator T Cassidy, AR Humphries Mathematical medicine and biology: a journal of the IMA 37 (1), 117-151, 2020 | 20 | 2020 |
Distributed delay differential equation representations of cyclic differential equations T Cassidy SIAM Journal on Applied Mathematics 81 (4), 1742-1766, 2021 | 17 | 2021 |
Characterizing chemotherapy-induced neutropenia and monocytopenia through mathematical modelling T Cassidy, AR Humphries, M Craig, MC Mackey Bulletin of Mathematical Biology 82, 1-26, 2020 | 13 | 2020 |
Immunological correlates of the HIV-1 replication-competent reservoir size SD Ismail, C Riou, SB Joseph, NM Archin, DM Margolis, AS Perelson, ... Clinical Infectious Diseases 73 (8), 1528-1531, 2021 | 8 | 2021 |
A continuation technique for maximum likelihood estimators in biological models T Cassidy Bulletin of Mathematical Biology 85 (90), 2023 | 6 | 2023 |
On the computation of eigenvalues of the anharmonic Coulombic potential T Cassidy, P Gaudreau, H Safouhi Journal of Mathematical Chemistry 56, 477-492, 2018 | 6 | 2018 |
Numerical methods and hypoexponential approximations for gamma distributed delay differential equations T Cassidy, P Gillich, AR Humphries, CH van Dorp IMA Journal of Applied Mathematics 87 (6), 1043-1089, 2022 | 3 | 2022 |
Growth rate-driven modelling reveals how phenotypic adaptation drives drug resistance in BRAFV600E-mutant melanoma S Hamis, AP Browning, AL Jenner, C Villa, P Maini, T Cassidy bioRxiv, 2024.08. 14.607616, 2024 | 1 | 2024 |
Modeling resistance to the broadly neutralizing antibody PGT121 in people living with HIV-1 T Cassidy, KE Stephenson, DH Barouch, AS Perelson PLOS Computational Biology 20 (3), e1011518, 2024 | 1 | 2024 |
On the development and application of distributed delay equations to mathematical physiology T Cassidy McGill University (Canada), 2019 | 1 | 2019 |
Using multi-delay discrete delay differential equations to accurately simulate models with distributed delays T Cassidy arXiv preprint arXiv:2410.09451, 2024 | | 2024 |
Reducing phenotype-structured PDE models of cancer evolution to systems of ODEs: a generalised moment dynamics approach C Villa, PK Maini, AP Browning, AL Jenner, S Hamis, T Cassidy arXiv preprint arXiv:2406.01505, 2024 | | 2024 |
An integrated quantitative systems pharmacology virtual population approach for calibration with oncology efficacy endpoints N Braniff, T Joshi, T Cassidy, M Trogdon, R Kumar, K Poels, R Allen, ... CPT: Pharmacometrics & Systems Pharmacology, 2024 | | 2024 |