| The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-β production L Pastorino, A Sun, PJ Lu, XZ Zhou, M Balastik, G Finn, G Wulf, J Lim, ... Nature 440 (7083), 528, 2006 | 576 | 2006 |
| Calcium/calmodulin‐dependent protein kinase II is associated with NR2A/B subunits of NMDA receptor in postsynaptic densities F Gardoni, A Caputi, M Cimino, L Pastorino, F Cattabeni, M Di Luca Journal of neurochemistry 71 (4), 1733-1741, 1998 | 245 | 1998 |
| JNK3 perpetuates metabolic stress induced by Aβ peptides SO Yoon, DJ Park, JC Ryu, HG Ozer, C Tep, YJ Shin, TH Lim, L Pastorino, ... Neuron 75 (5), 824-837, 2012 | 238 | 2012 |
| [alpha]-Secretase ADAM10 as well as [alpha] APPs is reduced in platelets and CSF of Alzheimer disease patients. F Colciaghi, B Borroni, L Pastorino, E Marcello, M Zimmermann, ... Molecular medicine 8 (2), 67, 2002 | 229 | 2002 |
| Peptidyl-prolyl cis–trans isomerase Pin1 in ageing, cancer and Alzheimer disease TH Lee, L Pastorino, KP Lu Expert reviews in molecular medicine 13, 2011 | 216 | 2011 |
| Differential level of platelet amyloid β precursor protein isoforms: an early marker for Alzheimer disease M Di Luca, L Pastorino, A Bianchetti, J Perez, LA Vignolo, GL Lenzi, ... Archives of neurology 55 (9), 1195-1200, 1998 | 186 | 1998 |
| The carboxyl-terminus of BACE contains a sorting signal that regulates BACE trafficking but not the formation of total Aβ L Pastorino, AF Ikin, AC Nairn, A Pursnani, JD Buxbaum Molecular and Cellular Neuroscience 19 (2), 175-185, 2002 | 157 | 2002 |
| BACE (β-secretase) modulates the processing of APLP2 in vivo L Pastorino, AF Ikin, S Lamprianou, N Vacaresse, JP Revelli, K Platt, ... Molecular and Cellular Neuroscience 25 (4), 642-649, 2004 | 149 | 2004 |
| Pin1 has opposite effects on wild-type and P301L tau stability and tauopathy J Lim, M Balastik, TH Lee, K Nakamura, YC Liou, A Sun, G Finn, ... The Journal of clinical investigation 118 (5), 1877-1889, 2008 | 132 | 2008 |
| Essential role of Pin1 in the regulation of TRF1 stability and telomere maintenance TH Lee, A Tun-Kyi, R Shi, J Lim, C Soohoo, G Finn, M Balastik, ... Nature cell biology 11 (1), 97, 2009 | 120 | 2009 |
| Pin1 in Alzheimer's disease: multiple substrates, one regulatory mechanism? M Balastik, J Lim, L Pastorino, KP Lu Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1772 (4), 422-429, 2007 | 119 | 2007 |
| Amyloid precursor protein in platelets A peripheral marker for the diagnosis of sporadic AD A Padovani, L Pastorino, B Borroni, F Colciaghi, L Rozzini, R Monastero, ... Neurology 57 (12), 2243-2248, 2001 | 111 | 2001 |
| Amyloid precursor protein in platelets of patients with Alzheimer disease: effect of acetylcholinesterase inhibitor treatment B Borroni, F Colciaghi, L Pastorino, C Pettenati, E Cottini, L Rozzini, ... Archives of neurology 58 (3), 442-446, 2001 | 108 | 2001 |
| Platelets as a peripheral district where to study pathogenetic mechanisms of Alzheimer disease: the case of amyloid precursor protein M Di Luca, F Colciaghi, L Pastorino, B Borroni, A Padovani, F Cattabeni European journal of pharmacology 405 (1-3), 277-283, 2000 | 108 | 2000 |
| Prolyl Isomerase Pin1 Promotes Amyloid Precursor Protein (APP) Turnover by Inhibiting Glycogen Synthase Kinase-3β (GSK3β) Activity NOVEL MECHANISM FOR Pin1 TO PROTECT AGAINST … SL Ma, L Pastorino, XZ Zhou, KP Lu Journal of Biological Chemistry 287 (10), 6969-6973, 2012 | 102 | 2012 |
| Abnormal pattern of platelet APP isoforms in Alzheimer disease and Down syndrome M Di Luca, L Pastorino, F Cattabeni, R Zanardi, S Scarone, G Racagni, ... Archives of neurology 53 (11), 1162-1166, 1996 | 93 | 1996 |
| Increased secretion of the amino‐terminal fragment of amyloid precursor protein in brains of rats with a constitutive up‐regulation of protein kinase C A Caputi, S Barindelli, L Pastorino, M Cimino, JD Buxbaum, F Cattabeni, ... Journal of neurochemistry 68 (6), 2523-2529, 1997 | 82 | 1997 |
| Pathogenic mechanisms in Alzheimer's disease L Pastorino, KP Lu European journal of pharmacology 545 (1), 29-38, 2006 | 74 | 2006 |
| A PIN1 polymorphism that prevents its suppression by AP4 associates with delayed onset of Alzheimer's disease SL Ma, NLS Tang, CWC Tam, VWC Lui, LCW Lam, HFK Chiu, JA Driver, ... Neurobiology of aging 33 (4), 804-813, 2012 | 72 | 2012 |
| ApoE genotype influences the biological effect of donepezil on APP metabolism in Alzheimer disease: evidence from a peripheral model B Borroni, F Colciaghi, L Pastorino, S Archetti, P Corsini, F Cattabeni, ... European neuropsychopharmacology 12 (3), 195-200, 2002 | 61 | 2002 |
