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Kevin Leder
Kevin Leder
Associate Professor of Industrial and Systems Engineering, University of Minnesota
Verified email at umn.edu
Title
Cited by
Cited by
Year
Mathematical modeling of PDGF-driven glioblastoma reveals optimized radiation dosing schedules
K Leder, K Pitter, Q LaPlant, D Hambardzumyan, BD Ross, TA Chan, ...
Cell 156 (3), 603-616, 2014
2452014
Intratumor heterogeneity in evolutionary models of tumor progression
R Durrett, J Foo, K Leder, J Mayberry, F Michor
Genetics 188 (2), 461-477, 2011
1332011
Importance sampling for sums of random variables with regularly varying tails
P Dupuis, K Leder, H Wang
ACM Transactions on Modeling and Computer Simulation (TOMACS) 17 (3), 14-es, 2007
852007
The impact of microenvironmental heterogeneity on the evolution of drug resistance in cancer cells
SM Mumenthaler, J Foo, NC Choi, N Heise, K Leder, DB Agus, W Pao, ...
Cancer informatics 14, CIN. S19338, 2015
842015
The therapeutic implications of plasticity of the cancer stem cell phenotype
K Leder, EC Holland, F Michor
PloS one 5 (12), e14366, 2010
642010
Fitness conferred by BCR-ABL kinase domain mutations determines the risk of pre-existing resistance in chronic myeloid leukemia
K Leder, J Foo, B Skaggs, M Gorre, CL Sawyers, F Michor
PloS one 6 (11), e27682, 2011
622011
Stochastic dynamics of cancer initiation
J Foo, K Leder, F Michor
Physical biology 8 (1), 015002, 2011
612011
Evolutionary dynamics of tumor progression with random fitness values
R Durrett, J Foo, K Leder, J Mayberry, F Michor
Theoretical population biology 78 (1), 54-66, 2010
592010
Evolutionary modeling of combination treatment strategies to overcome resistance to tyrosine kinase inhibitors in non-small cell lung cancer
SM Mumenthaler, J Foo, K Leder, NC Choi, DB Agus, W Pao, P Mallick, ...
Molecular pharmaceutics 8 (6), 2069-2079, 2011
562011
A mathematical model of tumor growth and its response to single irradiation
Y Watanabe, EL Dahlman, KZ Leder, SK Hui
Theoretical Biology and Medical Modelling 13 (1), 1-20, 2016
532016
Spatial Moran models, II: cancer initiation in spatially structured tissue
R Durrett, J Foo, K Leder
Journal of mathematical biology 72 (5), 1369-1400, 2016
37*2016
Multifocality and recurrence risk: a quantitative model of field cancerization
J Foo, K Leder, MD Ryser
Journal of theoretical biology 355, 170-184, 2014
372014
Optimization of radiation dosing schedules for proneural glioblastoma
H Badri, K Pitter, EC Holland, F Michor, K Leder
Journal of mathematical biology 72 (5), 1301-1336, 2016
352016
Quantifying the dynamics of field cancerization in tobacco-related head and neck cancer: a multiscale modeling approach
MD Ryser, WT Lee, NE Ready, KZ Leder, J Foo
Cancer research 76 (24), 7078-7088, 2016
342016
Efficient simulation of light-tailed sums: an old-folk song sung to a faster new tune...
JH Blanchet, K Leder, PW Glynn
Monte Carlo and Quasi-Monte Carlo Methods 2008, 227-248, 2009
34*2009
Optimal radiotherapy dose schedules under parametric uncertainty
H Badri, Y Watanabe, K Leder
Physics in Medicine & Biology 61 (1), 338, 2015
29*2015
Large deviations and importance sampling for a tandem network with slow-down
P Dupuis, K Leder, H Wang
Queueing Systems 57 (2), 71-83, 2007
282007
An evolutionary approach for identifying driver mutations in colorectal cancer
J Foo, LL Liu, K Leder, M Riester, Y Iwasa, C Lengauer, F Michor
PLoS computational biology 11 (9), e1004350, 2015
262015
Dynamics of cancer recurrence
J Foo, K Leder
The Annals of Applied Probability 23 (4), 1437-1468, 2013
262013
On Lyapunov inequalities and subsolutions for efficient importance sampling
J Blanchet, P Glynn, K Leder
ACM Transactions on Modeling and Computer Simulation (TOMACS) 22 (3), 1-27, 2012
262012
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