Katharine Best
Katharine Best
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Zika viral dynamics and shedding in rhesus and cynomolgus macaques
CE Osuna, SY Lim, C Deleage, BD Griffin, D Stein, LT Schroeder, ...
Nature medicine 22 (12), 1448, 2016
Zika virus persistence in the central nervous system and lymph nodes of rhesus monkeys
M Aid, P Abbink, RA Larocca, M Boyd, R Nityanandam, O Nanayakkara, ...
Cell 169 (4), 610-620. e14, 2017
T-cell receptor repertoires share a restricted set of public and abundant CDR3 sequences that are associated with self-related immunity
A Madi, E Shifrut, S Reich-Zeliger, H Gal, K Best, W Ndifon, B Chain, ...
Genome research 24 (10), 1603-1612, 2014
Tracking global changes induced in the CD4 T-cell receptor repertoire by immunization with a complex antigen using short stretches of CDR3 protein sequence
N Thomas, K Best, M Cinelli, S Reich-Zeliger, H Gal, E Shifrut, A Madi, ...
Bioinformatics 30 (22), 3181-3188, 2014
Quantitative characterization of the T cell receptor repertoire of na´ve and memory subsets using an integrated experimental and computational pipeline which is robustá…
T Oakes, JM Heather, K Best, R Byng-Maddick, C Husovsky, M Ismail, ...
Frontiers in immunology 8, 1267, 2017
Zika plasma viral dynamics in nonhuman primates provides insights into early infection and antiviral strategies
K Best, J Guedj, V Madelain, X de Lamballerie, SY Lim, CE Osuna, ...
Proceedings of the National Academy of Sciences 114 (33), 8847-8852, 2017
Blood transcriptomic diagnosis of pulmonary and extrapulmonary tuberculosis
JK Roe, N Thomas, E Gil, K Best, E Tsaliki, S Morris‑Jones, S Stafford, ...
JCI insight 1 (16), 2016
Computational analysis of stochastic heterogeneity in PCR amplification efficiency revealed by single molecule barcoding
K Best, T Oakes, JM Heather, J Shawe-Taylor, B Chain
Scientific reports 5 (1), 1-13, 2015
Dynamic perturbations of the T-cell receptor repertoire in chronic HIV infection and following antiretroviral therapy
JM Heather, K Best, T Oakes, ER Gray, JK Roe, N Thomas, N Friedman, ...
Frontiers in immunology 6, 644, 2016
Feature selection using a one dimensional na´ve Bayes' classifier increases the accuracy of support vector machine classification of CDR3 repertoires.
M Cinelli, Y Sun, K Best, JM Heather, S Reich-Zeliger, E Shifrut, ...
Bioinformatics 33 (7), 951-955, 2017
Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody
M Asokan, J Dias, C Liu, A Maximova, K Ernste, A Pegu, K McKee, W Shi, ...
Proceedings of the National Academy of Sciences 117 (31), 18754-18763, 2020
Mathematical modeling of within‐host Zika virus dynamics
K Best, AS Perelson
Immunological reviews 285 (1), 81-96, 2018
Specificity, privacy, and degeneracy in the CD4 T cell receptor repertoire following immunization
Y Sun, K Best, M Cinelli, JM Heather, S Reich-Zeliger, E Shifrut, ...
Frontiers in immunology 8, 430, 2017
The impact of DAMP-mediated inflammation in severe COVID-19 and related disorders
U Parthasarathy, R Martinelli, EH Vollmann, K Best, AG Therien
Biochemical Pharmacology 195, 114847, 2022
Principles governing establishment versus collapse of HIV-1 cellular spread
JM Hataye, JP Casazza, K Best, CJ Liang, TT Immonen, DR Ambrozak, ...
Cell host & microbe 26 (6), 748-763. e20, 2019
A direct-acting antiviral drug abrogates viremia in Zika virus–infected rhesus macaques
SY Lim, CE Osuna, K Best, R Taylor, E Chen, G Yoon, JL Kublin, D Schalk, ...
Science translational medicine 12 (547), eaau9135, 2020
The T cell response to the contact sensitizer paraphenylenediamine is characterized by a polyclonal diverse repertoire of antigen-specific receptors
T Oakes, AL Popple, J Williams, K Best, JM Heather, M Ismail, G Maxwell, ...
Frontiers in immunology 8, 162, 2017
Transcriptional profiling of endobronchial ultrasound-guided lymph node samples aids diagnosis of mediastinal lymphadenopathy
GS Tomlinson, N Thomas, BM Chain, K Best, N Simpson, G Hardavella, ...
Chest 149 (2), 535-544, 2016
Zika virus dynamics: Effects of inoculum dose, the innate immune response and viral interference
K Best, DH Barouch, J Guedj, RM Ribeiro, AS Perelson
PLoS computational biology 17 (1), e1008564, 2021
Pericyte derived chemokines amplify neutrophil recruitment across the cerebrovascular endothelial barrier.
E Gil, C Venturini, D Stirling, C Turner, LB Tezera, G Ercoli, T Baker, ...
Frontiers in immunology, 4149, 2022
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