| The extracellular matrix protein agrin promotes heart regeneration in mice E Bassat, YE Mutlak, A Genzelinakh, IY Shadrin, K Baruch Umansky, ... Nature 547 (7662), 179-184, 2017 | 603 | 2017 |
| Hippo signaling impedes adult heart regeneration T Heallen, Y Morikawa, J Leach, G Tao, JT Willerson, RL Johnson, ... Development 140 (23), 4683-4690, 2013 | 500 | 2013 |
| Hippo pathway deficiency reverses systolic heart failure after infarction JP Leach, T Heallen, M Zhang, M Rahmani, Y Morikawa, MC Hill, ... Nature 550 (7675), 260-264, 2017 | 387 | 2017 |
| Dystrophin–glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation Y Morikawa, T Heallen, J Leach, Y Xiao, JF Martin Nature 547 (7662), 227-231, 2017 | 265 | 2017 |
| YAP partially reprograms chromatin accessibility to directly induce adult cardiogenesis in vivo TO Monroe, MC Hill, Y Morikawa, JP Leach, T Heallen, S Cao, ... Developmental cell 48 (6), 765-779. e7, 2019 | 229 | 2019 |
| Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice Y Morikawa, M Zhang, T Heallen, J Leach, G Tao, Y Xiao, Y Bai, W Li, ... Science signaling 8 (375), ra41-ra41, 2015 | 229 | 2015 |
| Defining the role of pulmonary endothelial cell heterogeneity in the response to acute lung injury TK Niethamer, CT Stabler, JP Leach, JA Zepp, MP Morley, A Babu, ... Elife 9, e53072, 2020 | 193 | 2020 |
| Genomic, epigenomic, and biophysical cues controlling the emergence of the lung alveolus JA Zepp, MP Morley, C Loebel, MM Kremp, FN Chaudhry, MC Basil, ... Science 371 (6534), eabc3172, 2021 | 124 | 2021 |
| Age-dependent alveolar epithelial plasticity orchestrates lung homeostasis and regeneration IJ Penkala, DC Liberti, J Pankin, A Sivakumar, MM Kremp, ... Cell Stem Cell 28 (10), 1775-1789. e5, 2021 | 99 | 2021 |
| Gene therapy knockdown of Hippo signaling induces cardiomyocyte renewal in pigs after myocardial infarction S Liu, K Li, L Wagner Florencio, L Tang, TR Heallen, JP Leach, Y Wang, ... Science translational medicine 13 (600), eabd6892, 2021 | 96 | 2021 |
| Hippo/Yap signaling in cardiac development and regeneration Y Xiao, J Leach, J Wang, JF Martin Current treatment options in cardiovascular medicine 18, 1-9, 2016 | 61 | 2016 |
| Direct comparison of mononucleated and binucleated cardiomyocytes reveals molecular mechanisms underlying distinct proliferative competencies R Windmueller, JP Leach, A Babu, S Zhou, MP Morley, A Wakabayashi, ... Cell reports 30 (9), 3105-3116. e4, 2020 | 59 | 2020 |
| Long-range Pitx2c enhancer–promoter interactions prevent predisposition to atrial fibrillation M Zhang, MC Hill, ZA Kadow, JH Suh, NR Tucker, AW Hall, TT Tran, ... Proceedings of the National Academy of Sciences 116 (45), 22692-22698, 2019 | 52 | 2019 |
| Repairing the lungs one breath at a time: How dedicated or facultative are you? JP Leach, EE Morrisey Genes & development 32 (23-24), 1461-1471, 2018 | 48 | 2018 |
| Cardiomyocyte proliferation for therapeutic regeneration JP Leach, JF Martin Current cardiology reports 20 (8), 1-8, 2018 | 44 | 2018 |
| Biomechanical assessment of myocardial infarction using optical coherence elastography S Wang, M Singh, TT Tran, J Leach, SR Aglyamov, IV Larina, JF Martin, ... Biomedical Optics Express 9 (2), 728-742, 2018 | 37 | 2018 |
| A steroid receptor coactivator stimulator (MCB-613) attenuates adverse remodeling after myocardial infarction LK Mullany, AD Rohira, JP Leach, JH Kim, TO Monroe, AR Ortiz, B Stork, ... Proceedings of the National Academy of Sciences 117 (49), 31353-31364, 2020 | 26 | 2020 |
| Hippo and dystrophin complex signaling in cardiomyocyte renewal JF Martin, Y Morikawa, TR Heallen, J Leach | 18 | 2015 |
| Disruption of proteostasis causes IRE1 mediated reprogramming of alveolar epithelial cells J Katzen, L Rodriguez, Y Tomer, A Babu, M Zhao, A Murthy, P Carson, ... Proceedings of the National Academy of Sciences 119 (43), e2123187119, 2022 | 13 | 2022 |
| Temporal and spatial staging of lung alveolar regeneration is determined by the grainyhead transcription factor Tfcp2l1 FL Cardenas-Diaz, DC Liberti, JP Leach, A Babu, J Barasch, T Shen, ... Cell reports 42 (5), 2023 | 10 | 2023 |
Michael MorleyUniversity of PennsylvaniaVerified email at pennmedicine.upenn.edu
