Altered histone acetylation is associated with age-dependent memory impairment in mice S Peleg, F Sananbenesi, A Zovoilis, S Burkhardt, S Bahari-Javan, ... science 328 (5979), 753-756, 2010 | 1092 | 2010 |
Memory B cells activate brain-homing, autoreactive CD4+ T cells in multiple sclerosis I Jelcic, F Al Nimer, J Wang, V Lentsch, R Planas, I Jelcic, A Madjovski, ... Cell 175 (1), 85-100. e23, 2018 | 423 | 2018 |
Impact of RNA degradation on gene expression profiling L Opitz, G Salinas-Riester, M Grade, K Jung, P Jo, G Emons, BM Ghadimi, ... BMC medical genomics 3, 1-14, 2010 | 247 | 2010 |
The forebrain synaptic transcriptome is organized by clocks but its proteome is driven by sleep SB Noya, D Colameo, F Brüning, A Spinnler, D Mircsof, L Opitz, M Mann, ... Science 366 (6462), eaav2642, 2019 | 191 | 2019 |
HLA-DR15 molecules jointly shape an autoreactive T cell repertoire in multiple sclerosis J Wang, I Jelcic, L Mühlenbruch, V Haunerdinger, NC Toussaint, Y Zhao, ... Cell 183 (5), 1264-1281. e20, 2020 | 169 | 2020 |
Control of oligodendroglial cell number by the miR-17-92 cluster H Budde, S Schmitt, D Fitzner, L Opitz, G Salinas-Riester, M Simons Development 137 (13), 2127-2132, 2010 | 168 | 2010 |
Fate-mapping of GM-CSF expression identifies a discrete subset of inflammation-driving T helper cells regulated by cytokines IL-23 and IL-1β J Komuczki, S Tuzlak, E Friebel, T Hartwig, S Spath, P Rosenstiel, ... Immunity 50 (5), 1289-1304. e6, 2019 | 160 | 2019 |
A hippocampal insulin‐growth factor 2 pathway regulates the extinction of fear memories RC Agis‐Balboa, D Arcos‐Diaz, J Wittnam, N Govindarajan, K Blom, ... The EMBO journal 30 (19), 4071-4083, 2011 | 159 | 2011 |
RNASET2-deficient cystic leukoencephalopathy resembles congenital cytomegalovirus brain infection M Henneke, S Diekmann, A Ohlenbusch, J Kaiser, V Engelbrecht, ... Nature genetics 41 (7), 773-775, 2009 | 149 | 2009 |
CHD7, the gene mutated in CHARGE syndrome, regulates genes involved in neural crest cell guidance Y Schulz, P Wehner, L Opitz, G Salinas-Riester, EMHF Bongers, ... Human genetics 133, 997-1009, 2014 | 125 | 2014 |
Hemoglobinuria-related acute kidney injury is driven by intrarenal oxidative reactions triggering a heme toxicity response JW Deuel, CA Schaer, FS Boretti, L Opitz, I García-Rubio, JH Baek, ... Cell death & disease 7 (1), e2064-e2064, 2016 | 124 | 2016 |
Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease J Montag, R Hitt, L Opitz, WJ Schulz-Schaeffer, G Hunsmann, D Motzkus Molecular neurodegeneration 4, 1-7, 2009 | 124 | 2009 |
Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs G Sarker, W Sun, D Rosenkranz, P Pelczar, L Opitz, V Efthymiou, ... Proceedings of the National Academy of Sciences 116 (21), 10547-10556, 2019 | 123 | 2019 |
Populational equilibrium through exosome-mediated Wnt signaling in tumor progression of diffuse large B-cell lymphoma R Koch, M Demant, T Aung, N Diering, A Cicholas, B Chapuy, D Wenzel, ... Blood, The Journal of the American Society of Hematology 123 (14), 2189-2198, 2014 | 122 | 2014 |
Long fragments achieve lower base quality in Illumina paired-end sequencing G Tan, L Opitz, R Schlapbach, H Rehrauer Scientific reports 9 (1), 2856, 2019 | 118 | 2019 |
Oxidative burden and mitochondrial dysfunction in a mouse model of Rett syndrome E Grosser, U Hirt, OA Janc, C Menzfeld, M Fischer, B Kempkes, ... Neurobiology of disease 48 (1), 102-114, 2012 | 116 | 2012 |
Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring W Sun, H Dong, AS Becker, DH Dapito, S Modica, G Grandl, L Opitz, ... Nature medicine 24 (9), 1372-1383, 2018 | 111 | 2018 |
The COP9 signalosome mediates transcriptional and metabolic response to hormones, oxidative stress protection and cell wall rearrangement during fungal development K Nahlik, M Dumkow, Ö Bayram, K Helmstaedt, S Busch, O Valerius, ... Molecular microbiology 78 (4), 964-979, 2010 | 107 | 2010 |
Peroxisome proliferator activated receptor gamma controls mature brown adipocyte inducibility through glycerol kinase D Lasar, M Rosenwald, E Kiehlmann, M Balaz, B Tall, L Opitz, ME Lidell, ... Cell reports 22 (3), 760-773, 2018 | 105 | 2018 |
Tissue-specific transcriptomics, chromosomal localization, and phylogeny of chemosensory and odorant binding proteins from the red flour beetle Tribolium castaneum reveal … S Dippel, G Oberhofer, J Kahnt, L Gerischer, L Opitz, J Schachtner, ... BMC genomics 15, 1-14, 2014 | 104 | 2014 |