Mark A Magnuson
Mark A Magnuson
Vahvistettu sähköpostiosoite verkkotunnuksessa
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
MF Offield, TL Jetton, PA Labosky, M Ray, RW Stein, MA Magnuson, ...
Development 122 (3), 983-995, 1996
Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction
MD Michael, RN Kulkarni, C Postic, SF Previs, GI Shulman, ...
Molecular cell 6 (1), 87-97, 2000
Tissue-specific knockout of the insulin receptor in pancreatic β cells creates an insulin secretory defect similar to that in type 2 diabetes
RN Kulkarni, JC Brüning, JN Winnay, C Postic, MA Magnuson, CR Kahn
Cell 96 (3), 329-339, 1999
Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic β cell-specific gene knock-outs using Cre recombinase
C Postic, M Shiota, KD Niswender, TL Jetton, Y Chen, JM Moates, ...
Journal of Biological Chemistry 274 (1), 305-315, 1999
Thiazolidinediones expand body fluid volume through PPARγ stimulation of ENaC-mediated renal salt absorption
YF Guan, C Hao, DR Cha, R Rao, W Lu, DE Kohan, MA Magnuson, ...
Nature medicine 11 (8), 861-866, 2005
Identification of Protor as a novel Rictor-binding component of mTOR complex-2
LR Pearce, X Huang, J Boudeau, R Pawłowski, S Wullschleger, M Deak, ...
Biochemical Journal 405 (3), 513-522, 2007
Allosteric activators of glucokinase: potential role in diabetes therapy
J Grimsby, R Sarabu, WL Corbett, NE Haynes, FT Bizzarro, JW Coffey, ...
Science 301 (5631), 370-373, 2003
Deletion of PPARγ in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance
JR Jones, C Barrick, KA Kim, J Lindner, B Blondeau, Y Fujimoto, M Shiota, ...
Proceedings of the National Academy of Sciences 102 (17), 6207-6212, 2005
Neonatal diabetes mellitus due to complete glucokinase deficiency
PR Njølstad, O Søvik, A Cuesta-Muñoz, L Bjørkhaug, O Massa, F Barbetti, ...
New England Journal of Medicine 344 (21), 1588-1592, 2001
Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression
R Dentin, JP Pégorier, F Benhamed, F Foufelle, P Ferré, V Fauveau, ...
Journal of Biological Chemistry 279 (19), 20314-20326, 2004
Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways
K Lee, P Gudapati, S Dragovic, C Spencer, S Joyce, N Killeen, ...
Immunity 32 (6), 743-753, 2010
Impaired insulin secretion and β-cell loss in tissue-specific knockout mice with mitochondrial diabetes
JP Silva, M Köhler, C Graff, A Oldfors, MA Magnuson, PO Berggren, ...
Nature genetics 26 (3), 336-340, 2000
Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity
B Stiles, Y Wang, A Stahl, S Bassilian, WP Lee, YJ Kim, R Sherwin, ...
Proceedings of the National Academy of Sciences 101 (7), 2082-2087, 2004
mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice
DA Guertin, DM Stevens, M Saitoh, S Kinkel, K Crosby, JH Sheen, ...
Cancer cell 15 (2), 148-159, 2009
Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability
C Shiota, JT Woo, J Lindner, KD Shelton, MA Magnuson
Developmental cell 11 (4), 583-589, 2006
Salt–sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor
CRJ Kennedy, Y Zhang, S Brandon, Y Guan, K Coffee, CD Funk, ...
Nature medicine 5 (2), 217-220, 1999
β-cell–specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter β-cell mass
RN Kulkarni, M Holzenberger, DQ Shih, U Ozcan, M Stoffel, ...
Nature genetics 31 (1), 111-115, 2002
Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities.
FM Matschinsky, B Glaser, MA Magnuson
Diabetes 47 (3), 307-315, 1998
DNA excision in liver by an albumin‐Cre transgene occurs progressively with age
C Postic, MA Magnuson
genesis 26 (2), 149-150, 2000
Identification of a sequence in the PEPCK gene that mediates a negative effect of insulin on transcription
RM O'Brien, PC Lucas, CD Forest, MA Magnuson, DK Granner
Science 249 (4968), 533-537, 1990
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Artikkelit 1–20