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Kazuhiko Igarashi
Kazuhiko Igarashi
Department of Biochemistry, Tohoku University Graduate School of Medicine
Verified email at med.tohoku.ac.jp - Homepage
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Year
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
K Itoh, T Chiba, S Takahashi, T Ishii, K Igarashi, Y Katoh, T Oyake, ...
Biochemical and biophysical research communications 236 (2), 313-322, 1997
43371997
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
K Itoh, N Wakabayashi, Y Katoh, T Ishii, K Igarashi, JD Engel, ...
Genes & development 13 (1), 76-86, 1999
39291999
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
A Kobayashi, MI Kang, H Okawa, M Ohtsuji, Y Zenke, T Chiba, K Igarashi, ...
Molecular and cellular biology 24 (16), 7130-7139, 2004
23812004
A third recognition element in bacterial promoters: DNA binding by the α subunit of RNA polymerase
W Ross, KK Gosink, J Salomon, K Igarashi, C Zou, A Ishihama, ...
Science 262 (5138), 1407-1413, 1993
10011993
Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene
J Sun, H Hoshino, K Takaku, O Nakajima, A Muto, H Suzuki, S Tashiro, ...
The EMBO journal 21 (19), 5216-5224, 2002
7422002
Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site
T Oyake, K Itoh, H Motohashi, N Hayashi, H Hoshino, M Nishizawa, ...
Molecular and cellular biology 16 (11), 6083-6095, 1996
7351996
Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1
K Ogawa, J Sun, S Taketani, O Nakajima, C Nishitani, S Sassa, ...
The EMBO journal 20 (11), 2835-2843, 2001
6242001
Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins
K Igarashi, K Kataokat, K Itoh, N Hayashi, M Nishizawa, M Yamamoto
Nature 367 (6463), 568-572, 1994
5411994
Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteins
K Itoh, K Igarashi, N Hayashi, M Nishizawa, M Yamamoto
Molecular and cellular biology 15 (8), 4184-4193, 1995
5141995
DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics
T Ikura, S Tashiro, A Kakino, H Shima, N Jacob, R Amunugama, K Yoder, ...
Molecular and cellular biology 27 (20), 7028-7040, 2007
4342007
Bipartite functional map of the E. coli RNA polymerase α subunit: involvement of the C-terminal region in transcription activation by cAMP-CRP
K Igarashi, A Ishihama
Cell 65 (6), 1015-1022, 1991
4231991
Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages
M Haldar, M Kohyama, AYL So, KC Wumesh, X Wu, CG Briseño, ...
Cell 156 (6), 1223-1234, 2014
4182014
Heme regulates the dynamic exchange of Bach1 and NF-E2-related factors in the Maf transcription factor network
J Sun, M Brand, Y Zenke, S Tashiro, M Groudine, K Igarashi
Proceedings of the National Academy of Sciences 101 (6), 1461-1466, 2004
4162004
BACH2 represses effector programs to stabilize Treg-mediated immune homeostasis
R Roychoudhuri, K Hirahara, K Mousavi, D Clever, CA Klebanoff, ...
Nature 498 (7455), 506-510, 2013
4112013
Molecular cloning and functional characterization of a new Cap'n'collar family transcription factor Nrf3
A Kobayashi, E Ito, T Toki, K Kogame, S Takahashi, K Igarashi, N Hayashi, ...
Journal of Biological Chemistry 274 (10), 6443-6452, 1999
3631999
Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1–NRF2 pathway, and not the BACH1–NRF2 pathway …
AK MacLeod, M McMahon, SM Plummer, LG Higgins, TM Penning, ...
Carcinogenesis 30 (9), 1571-1580, 2009
3472009
The world according to Maf
H Motohashi, JA Shavit, K Igarashi, M Yamamoto, JD Engel
Nucleic acids research 25 (15), 2953-2959, 1997
3361997
The transcriptional programme of antibody class switching involves the repressor Bach2
A Muto, S Tashiro, O Nakajima, H Hoshino, S Takahashi, E Sakoda, ...
Nature 429 (6991), 566-571, 2004
3342004
The superoxide‐producing NAD (P) H oxidase Nox4 in the nucleus of human vascular endothelial cells
J Kuroda, K Nakagawa, T Yamasaki, K Nakamura, R Takeya, ...
Genes to Cells 10 (12), 1139-1151, 2005
3272005
Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells
T Kitamuro, K Takahashi, K Ogawa, R Udono-Fujimori, K Takeda, ...
Journal of Biological Chemistry 278 (11), 9125-9133, 2003
3202003
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