Caroline Heckman
Caroline Heckman
University of Helsinki, Institute for Molecular Medicine Finland FIMM-HiLIFE
Verified email at - Homepage
TitleCited byYear
Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia
HLM Koskela, S Eldfors, P Ellonen, AJ van Adrichem, H Kuusanmäki, ...
New England Journal of Medicine 366 (20), 1905-1913, 2012
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
T Kärpänen, CA Heckman, S Keskitalo, M Jeltsch, H Ollila, G Neufeld, ...
The FASEB Journal 20 (9), 1462-1472, 2006
Histone deacetylase inhibitors down-regulate bcl-2 expression and induce apoptosis in t (14; 18) lymphomas
H Duan, CA Heckman, LM Boxer
Molecular and cellular biology 25 (5), 1608-1619, 2005
Negative regulation of bcl-2 expression by p53 in hematopoietic cells
Y Wu, JW Mehew, CA Heckman, M Arcinas, LM Boxer
Oncogene 20 (2), 240, 2001
Comparison of solution-based exome capture methods for next generation sequencing
AM Sulonen, P Ellonen, H Almusa, M Lepistö, S Eldfors, S Hannula, ...
Genome biology 12 (9), R94, 2011
Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia
T Pemovska, M Kontro, B Yadav, H Edgren, S Eldfors, A Szwajda, ...
Cancer discovery 3 (12), 1416-1429, 2013
NF-κB activates Bcl-2 expression in t (14; 18) lymphoma cells
CA Heckman, JW Mehew, LM Boxer
Oncogene 21 (24), 3898, 2002
Use of cancer‐specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors
DJ McBride, AK Orpana, C Sotiriou, H Joensuu, PJ Stephens, LJ Mudie, ...
Genes, Chromosomes and Cancer 49 (11), 1062-1069, 2010
Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia
HLM Rajala, S Eldfors, H Kuusanmäki, AJ Van Adrichem, T Olson, ...
Blood 121 (22), 4541-4550, 2013
Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies
B Yadav, T Pemovska, A Szwajda, E Kulesskiy, M Kontro, R Karjalainen, ...
Scientific reports 4, 5193, 2014
The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis
CA Heckman, T Holopainen, M Wirzenius, S Keskitalo, M Jeltsch, ...
Cancer Research 68 (12), 4754-4762, 2008
The WT1 Protein Is a Negative Regulator of the Normalbcl-2 Allele in t (14; 18) Lymphomas
C Heckman, E Mochon, M Arcinas, LM Boxer
Journal of Biological Chemistry 272 (31), 19609-19614, 1997
A-Myb up-regulates Bcl-2 through a Cdx binding site in t (14; 18) lymphoma cells
CA Heckman, JW Mehew, GG Ying, M Introna, J Golay, LM Boxer
Journal of Biological Chemistry 275 (9), 6499-6508, 2000
Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia
M Kontro, H Kuusanmäki, S Eldfors, T Burmeister, EI Andersson, ...
Leukemia 28 (8), 1738, 2014
Molecular mechanisms of transcriptional control of bcl-2 and c-myc in follicular and transformed lymphoma
M Arcinas, CA Heckman, JW Mehew, LM Boxer
Cancer research 61 (13), 5202-5206, 2001
CCAAT/enhancer binding protein α (C/EBPα) and C/EBPα myeloid oncoproteins induce bcl-2 via interaction of their basic regions with nuclear factor-κB p50
I Paz-Priel, DH Cai, D Wang, J Kowalski, A Blackford, H Liu, CA Heckman, ...
Molecular Cancer Research 3 (10), 585-596, 2005
Novel somatic mutations in large granular lymphocytic leukemia affecting the STAT-pathway and T-cell activation
EI Andersson, HLM Rajala, S Eldfors, P Ellonen, T Olson, A Jerez, ...
Blood cancer journal 3 (12), e168, 2013
Regulation of Bcl-2 expression by C/EBP in t (14; 18) lymphoma cells
CA Heckman, MA Wheeler, LM Boxer
Oncogene 22 (39), 7891, 2003
HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia
M Kontro, A Kumar, MM Majumder, S Eldfors, A Parsons, T Pemovska, ...
Leukemia 31 (2), 301, 2017
Oct transcription factors mediate t (14; 18) lymphoma cell survival by directly regulating bcl-2 expression
CA Heckman, H Duan, PB Garcia, LM Boxer
Oncogene 25 (6), 888-898, 2006
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