| Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia HLM Koskela, S Eldfors, P Ellonen, AJ van Adrichem, H Kuusanmäki, ... New England Journal of Medicine 366 (20), 1905-1913, 2012 | 490 | 2012 |
| Functional interaction of VEGF-C and VEGF-D with neuropilin receptors T Kärpänen, CA Heckman, S Keskitalo, M Jeltsch, H Ollila, G Neufeld, ... The FASEB Journal 20 (9), 1462-1472, 2006 | 317 | 2006 |
| Histone deacetylase inhibitors down-regulate bcl-2 expression and induce apoptosis in t (14; 18) lymphomas H Duan, CA Heckman, LM Boxer Molecular and cellular biology 25 (5), 1608-1619, 2005 | 272 | 2005 |
| Negative regulation of bcl-2 expression by p53 in hematopoietic cells Y Wu, JW Mehew, CA Heckman, M Arcinas, LM Boxer Oncogene 20 (2), 240, 2001 | 258 | 2001 |
| Comparison of solution-based exome capture methods for next generation sequencing AM Sulonen, P Ellonen, H Almusa, M Lepistö, S Eldfors, S Hannula, ... Genome biology 12 (9), R94, 2011 | 240 | 2011 |
| Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia T Pemovska, M Kontro, B Yadav, H Edgren, S Eldfors, A Szwajda, ... Cancer discovery 3 (12), 1416-1429, 2013 | 219* | 2013 |
| NF-κB activates Bcl-2 expression in t (14; 18) lymphoma cells CA Heckman, JW Mehew, LM Boxer Oncogene 21 (24), 3898, 2002 | 215 | 2002 |
| Use of cancer‐specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors DJ McBride, AK Orpana, C Sotiriou, H Joensuu, PJ Stephens, LJ Mudie, ... Genes, Chromosomes and Cancer 49 (11), 1062-1069, 2010 | 203 | 2010 |
| Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia HLM Rajala, S Eldfors, H Kuusanmäki, AJ Van Adrichem, T Olson, ... Blood 121 (22), 4541-4550, 2013 | 185 | 2013 |
| Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies B Yadav, T Pemovska, A Szwajda, E Kulesskiy, M Kontro, R Karjalainen, ... Scientific reports 4, 5193, 2014 | 115 | 2014 |
| The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis CA Heckman, T Holopainen, M Wirzenius, S Keskitalo, M Jeltsch, ... Cancer Research 68 (12), 4754-4762, 2008 | 108 | 2008 |
| The WT1 Protein Is a Negative Regulator of the Normalbcl-2 Allele in t (14; 18) Lymphomas C Heckman, E Mochon, M Arcinas, LM Boxer Journal of Biological Chemistry 272 (31), 19609-19614, 1997 | 97 | 1997 |
| A-Myb up-regulates Bcl-2 through a Cdx binding site in t (14; 18) lymphoma cells CA Heckman, JW Mehew, GG Ying, M Introna, J Golay, LM Boxer Journal of Biological Chemistry 275 (9), 6499-6508, 2000 | 72 | 2000 |
| Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia M Kontro, H Kuusanmäki, S Eldfors, T Burmeister, EI Andersson, ... Leukemia 28 (8), 1738, 2014 | 65 | 2014 |
| Molecular mechanisms of transcriptional control of bcl-2 and c-myc in follicular and transformed lymphoma M Arcinas, CA Heckman, JW Mehew, LM Boxer Cancer research 61 (13), 5202-5206, 2001 | 64 | 2001 |
| CCAAT/enhancer binding protein α (C/EBPα) and C/EBPα myeloid oncoproteins induce bcl-2 via interaction of their basic regions with nuclear factor-κB p50 I Paz-Priel, DH Cai, D Wang, J Kowalski, A Blackford, H Liu, CA Heckman, ... Molecular Cancer Research 3 (10), 585-596, 2005 | 58 | 2005 |
| Novel somatic mutations in large granular lymphocytic leukemia affecting the STAT-pathway and T-cell activation EI Andersson, HLM Rajala, S Eldfors, P Ellonen, T Olson, A Jerez, ... Blood cancer journal 3 (12), e168, 2013 | 45 | 2013 |
| Regulation of Bcl-2 expression by C/EBP in t (14; 18) lymphoma cells CA Heckman, MA Wheeler, LM Boxer Oncogene 22 (39), 7891, 2003 | 44 | 2003 |
| HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia M Kontro, A Kumar, MM Majumder, S Eldfors, A Parsons, T Pemovska, ... Leukemia 31 (2), 301, 2017 | 42 | 2017 |
| Oct transcription factors mediate t (14; 18) lymphoma cell survival by directly regulating bcl-2 expression CA Heckman, H Duan, PB Garcia, LM Boxer Oncogene 25 (6), 888-898, 2006 | 41 | 2006 |
