Caroline Heckman
Caroline Heckman
University of Helsinki, Institute for Molecular Medicine Finland FIMM-HiLIFE
Verified email at helsinki.fi - Homepage
TitleCited byYear
Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia
HLM Koskela, S Eldfors, P Ellonen, AJ van Adrichem, H Kuusanmäki, ...
New England Journal of Medicine 366 (20), 1905-1913, 2012
4902012
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
T Kärpänen, CA Heckman, S Keskitalo, M Jeltsch, H Ollila, G Neufeld, ...
The FASEB Journal 20 (9), 1462-1472, 2006
3172006
Histone deacetylase inhibitors down-regulate bcl-2 expression and induce apoptosis in t (14; 18) lymphomas
H Duan, CA Heckman, LM Boxer
Molecular and cellular biology 25 (5), 1608-1619, 2005
2722005
Negative regulation of bcl-2 expression by p53 in hematopoietic cells
Y Wu, JW Mehew, CA Heckman, M Arcinas, LM Boxer
Oncogene 20 (2), 240, 2001
2582001
Comparison of solution-based exome capture methods for next generation sequencing
AM Sulonen, P Ellonen, H Almusa, M Lepistö, S Eldfors, S Hannula, ...
Genome biology 12 (9), R94, 2011
2402011
Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia
T Pemovska, M Kontro, B Yadav, H Edgren, S Eldfors, A Szwajda, ...
Cancer discovery 3 (12), 1416-1429, 2013
219*2013
NF-κB activates Bcl-2 expression in t (14; 18) lymphoma cells
CA Heckman, JW Mehew, LM Boxer
Oncogene 21 (24), 3898, 2002
2152002
Use of cancer‐specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors
DJ McBride, AK Orpana, C Sotiriou, H Joensuu, PJ Stephens, LJ Mudie, ...
Genes, Chromosomes and Cancer 49 (11), 1062-1069, 2010
2032010
Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia
HLM Rajala, S Eldfors, H Kuusanmäki, AJ Van Adrichem, T Olson, ...
Blood 121 (22), 4541-4550, 2013
1852013
Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies
B Yadav, T Pemovska, A Szwajda, E Kulesskiy, M Kontro, R Karjalainen, ...
Scientific reports 4, 5193, 2014
1152014
The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis
CA Heckman, T Holopainen, M Wirzenius, S Keskitalo, M Jeltsch, ...
Cancer Research 68 (12), 4754-4762, 2008
1082008
The WT1 Protein Is a Negative Regulator of the Normalbcl-2 Allele in t (14; 18) Lymphomas
C Heckman, E Mochon, M Arcinas, LM Boxer
Journal of Biological Chemistry 272 (31), 19609-19614, 1997
971997
A-Myb up-regulates Bcl-2 through a Cdx binding site in t (14; 18) lymphoma cells
CA Heckman, JW Mehew, GG Ying, M Introna, J Golay, LM Boxer
Journal of Biological Chemistry 275 (9), 6499-6508, 2000
722000
Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia
M Kontro, H Kuusanmäki, S Eldfors, T Burmeister, EI Andersson, ...
Leukemia 28 (8), 1738, 2014
652014
Molecular mechanisms of transcriptional control of bcl-2 and c-myc in follicular and transformed lymphoma
M Arcinas, CA Heckman, JW Mehew, LM Boxer
Cancer research 61 (13), 5202-5206, 2001
642001
CCAAT/enhancer binding protein α (C/EBPα) and C/EBPα myeloid oncoproteins induce bcl-2 via interaction of their basic regions with nuclear factor-κB p50
I Paz-Priel, DH Cai, D Wang, J Kowalski, A Blackford, H Liu, CA Heckman, ...
Molecular Cancer Research 3 (10), 585-596, 2005
582005
Novel somatic mutations in large granular lymphocytic leukemia affecting the STAT-pathway and T-cell activation
EI Andersson, HLM Rajala, S Eldfors, P Ellonen, T Olson, A Jerez, ...
Blood cancer journal 3 (12), e168, 2013
452013
Regulation of Bcl-2 expression by C/EBP in t (14; 18) lymphoma cells
CA Heckman, MA Wheeler, LM Boxer
Oncogene 22 (39), 7891, 2003
442003
HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia
M Kontro, A Kumar, MM Majumder, S Eldfors, A Parsons, T Pemovska, ...
Leukemia 31 (2), 301, 2017
422017
Oct transcription factors mediate t (14; 18) lymphoma cell survival by directly regulating bcl-2 expression
CA Heckman, H Duan, PB Garcia, LM Boxer
Oncogene 25 (6), 888-898, 2006
412006
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