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Michael Tymianski
Michael Tymianski
University Health Network
Verified email at uhn.ca
Title
Cited by
Cited by
Year
Unruptured intracranial aneurysms—risk of rupture and risks of surgical intervention
International Study of Unruptured Intracranial Aneurysms Investigators
New England Journal of Medicine 339 (24), 1725-1733, 1998
15621998
Glutamate receptors, neurotoxicity and neurodegeneration
A Lau, M Tymianski
Pflügers Archiv-European Journal of Physiology 460, 525-542, 2010
13632010
Treatment of ischemic brain damage by perturbing NMDA receptor-PSD-95 protein interactions
M Aarts, Y Liu, L Liu, S Besshoh, M Arundine, JW Gurd, YT Wang, ...
Science 298 (5594), 846-850, 2002
12482002
Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity
M Arundine, M Tymianski
Cell calcium 34 (4-5), 325-337, 2003
10922003
Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein
R Sattler, Z Xiong, WY Lu, M Hafner, JF MacDonald, M Tymianski
Science 284 (5421), 1845-1848, 1999
10921999
NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo
Y Liu, TP Wong, M Aarts, A Rooyakkers, L Liu, TW Lai, DC Wu, J Lu, ...
Journal of Neuroscience 27 (11), 2846-2857, 2007
9852007
Calcium, ischemia and excitotoxicity
K Szydlowska, M Tymianski
Cell calcium 47 (2), 122-129, 2010
9522010
A key role for TRPM7 channels in anoxic neuronal death
M Aarts, K Iihara, WL Wei, ZG Xiong, M Arundine, W Cerwinski, ...
Cell 115 (7), 863-877, 2003
9452003
Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury
M Arundine, M Tymianski
Cellular and Molecular Life Sciences CMLS 61, 657-668, 2004
8832004
Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons
M Tymianski, MP Charlton, PL Carlen, CH Tator
Journal of Neuroscience 13 (5), 2085-2104, 1993
7571993
Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death
R Sattler, M Tymianski
Molecular neurobiology 24, 107-129, 2001
7352001
Molecular mechanisms of calcium-dependent excitotoxicity
R Sattler, M Tymianski
Journal of molecular medicine 78, 3-13, 2000
6452000
Normal and abnormal calcium homeostasis in neurons: a basis for the pathophysiology of traumatic and ischemic central nervous system injury
M Tymianski, CH Tator
Neurosurgery 38 (6), 1176-1195, 1996
4851996
The natural history and predictive features of hemorrhage from brain arteriovenous malformations
L da Costa, MC Wallace, KG Ter Brugge, C O'Kelly, RA Willinsky, ...
Stroke 40 (1), 100-105, 2009
4732009
Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain
DJ Cook, L Teves, M Tymianski
Nature 483 (7388), 213-217, 2012
4652012
Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial
MD Hill, M Goyal, BK Menon, RG Nogueira, RA McTaggart, AM Demchuk, ...
The Lancet 395 (10227), 878-887, 2020
4612020
Safety and efficacy of NA-1 in patients with iatrogenic stroke after endovascular aneurysm repair (ENACT): a phase 2, randomised, double-blind, placebo-controlled trial
MD Hill, RH Martin, D Mikulis, JH Wong, FL Silver, G Milot, WM Clark, ...
The Lancet Neurology 11 (11), 942-950, 2012
4142012
Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity
R Sattler, MP Charlton, M Hafner, M Tymianski
Journal of neurochemistry 71 (6), 2349-2364, 1998
3571998
Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia
HS Sun, MF Jackson, LJ Martin, K Jansen, L Teves, H Cui, S Kiyonaka, ...
Nature neuroscience 12 (10), 1300-1307, 2009
3152009
Distinct roles of synaptic and extrasynaptic NMDA receptors in excitotoxicity
R Sattler, Z Xiong, WY Lu, JF MacDonald, M Tymianski
Journal of Neuroscience 20 (1), 22-33, 2000
3132000
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