| Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes R Karki, BR Sharma, S Tuladhar, EP Williams, L Zalduondo, P Samir, ... Cell 184 (1), 149-168. e17, 2021 | 1139 | 2021 |
| NLRP3 inflammasome in cancer and metabolic diseases BR Sharma, TD Kanneganti Nature immunology 22 (5), 550-559, 2021 | 531 | 2021 |
| DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome P Samir, S Kesavardhana, DM Patmore, S Gingras, RKS Malireddi, ... Nature 573 (7775), 590-594, 2019 | 293 | 2019 |
| Identification of the PANoptosome: a molecular platform triggering pyroptosis, apoptosis, and necroptosis (PANoptosis) S Christgen, M Zheng, S Kesavardhana, R Karki, RKS Malireddi, ... Frontiers in cellular and infection microbiology 10, 237, 2020 | 270 | 2020 |
| Role of AIM2 inflammasome in inflammatory diseases, cancer and infection BR Sharma, R Karki, TD Kanneganti European journal of immunology 49 (11), 1998-2011, 2019 | 205 | 2019 |
| ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis R Karki, B Sundaram, BR Sharma, SJ Lee, RKS Malireddi, LN Nguyen, ... Cell reports 37 (3), 2021 | 178 | 2021 |
| NLRC3 is an inhibitory sensor of PI3K–mTOR pathways in cancer R Karki, SM Man, RKS Malireddi, S Kesavardhana, Q Zhu, AR Burton, ... Nature 540 (7634), 583-587, 2016 | 177 | 2016 |
| IRF8 regulates transcription of Naips for NLRC4 inflammasome activation R Karki, D Place, P Samir, J Mavuluri, BR Sharma, A Balakrishnan, ... Cell 173 (4), 920-933. e13, 2018 | 160 | 2018 |
| Interferon regulatory factor 1 regulates PANoptosis to prevent colorectal cancer R Karki, BR Sharma, B Banoth, RKS Malireddi, P Samir, S Tuladhar, ... JCI insight 5 (12), 2020 | 152 | 2020 |
| A Comprehensive Review on Chemical Profiling of Nelumbo Nucifera: Potential for Drug Development BR Sharma, LNS Gautam, D Adhikari, R Karki Phytotherapy Research 31 (1), 3-26, 2017 | 150 | 2017 |
| Caulerpa lentillifera extract ameliorates insulin resistance and regulates glucose metabolism in C57BL/KsJ-db/db mice via PI3K/AKT signaling pathway in myocytes BR Sharma, HJ Kim, DY Rhyu Journal of Translational Medicine 13, 1-10, 2015 | 109 | 2015 |
| ZBP1 promotes fungi-induced inflammasome activation and pyroptosis, apoptosis, and necroptosis (PANoptosis) B Banoth, S Tuladhar, R Karki, BR Sharma, B Briard, S Kesavardhana, ... Journal of Biological Chemistry 295 (52), 18276-18283, 2020 | 107 | 2020 |
| Anti-diabetic effects of Caulerpa lentillifera: stimulation of insulin secretion in pancreatic β-cells and enhancement of glucose uptake in adipocytes BR Sharma, DY Rhyu Asian Pacific journal of tropical biomedicine 4 (7), 575-580, 2014 | 102 | 2014 |
| ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection R Karki, SJ Lee, R Mall, N Pandian, Y Wang, BR Sharma, RKS Malireddi, ... Science immunology 7 (74), eabo6294, 2022 | 98 | 2022 |
| Alkaloid rich fraction from Nelumbo nucifera targets VSMC proliferation and migration to suppress restenosis in balloon-injured rat carotid artery MY Jun, R Karki, KR Paudel, BR Sharma, D Adhikari, DW Kim Atherosclerosis 248, 179-189, 2016 | 73 | 2016 |
| Role of Reactive Oxygen Species in Transforming Growth Factor-Beta1–Induced Extracellular Matrix Accumulation in Renal Tubular Epithelial Cells DY Rhyu, J Park, BR Sharma, H Ha Transplantation proceedings 44 (3), 625-628, 2012 | 51 | 2012 |
| Caulerpa okamurae extract inhibits adipogenesis in 3T3-L1 adipocytes and prevents high-fat diet–induced obesity in C57BL/6 mice BR Sharma, HJ Kim, MS Kim, CM Park, DY Rhyu Nutrition research 47, 44-52, 2017 | 43 | 2017 |
| Anti-Obesity Effects of the Mixture of Eriobotrya japonica and Nelumbo nucifera in Adipocytes and High-Fat Diet-Induced Obese Mice BR Sharma, J Oh, HA Kim, YJ Kim, KS Jeong, DY Rhyu The American Journal of Chinese Medicine 43 (04), 681-694, 2015 | 40 | 2015 |
| DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response S Kesavardhana, P Samir, M Zheng, RKS Malireddi, R Karki, BR Sharma, ... Journal of Biological Chemistry 296, 2021 | 37 | 2021 |
| Inflammasome signaling in colorectal cancer BR Sharma, TD Kanneganti Translational Research 252, 45-52, 2023 | 34 | 2023 |
Thirumala-Devi KannegantiSt. Jude Children's Research HospitalVerified email at stjude.org
